Nearly everyone is overtired or overworked from time to time. Such instances of temporary fatigue usually have an identifiable cause and a likely remedy.

Unrelenting exhaustion, on the other hand, lasts longer, is more profound and isn't relieved by rest. It's a nearly constant state of weariness that develops over time and reduces your energy, motivation and concentration. Fatigue at this level impacts your emotional and psychological well-being, too.

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Dec. 02, 2020

See also

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  2. Acetyl-L-carnitine: Can it relieve MS fatigue?
  3. Acromegaly
  4. Acute bronchitis: Is it contagious?
  5. Acute hepatitis C infection
  6. Acute kidney failure
  7. Acute lymphocytic leukemia
  8. Acute myelogenous leukemia
  9. Acute sinusitis
  10. Acute sinusitis: Do over-the-counter treatments help?
  11. Addison's disease
  12. Adjuvant therapy for cancer
  13. Adrenal fatigue: What causes it?
  14. Alcoholic hepatitis
  15. Alternative cancer treatments: 10 options to consider
  16. Ambien: Is dependence a concern?
  17. Amputation and diabetes
  18. Amyloidosis
  19. Anaphylaxis
  20. Anemia
  21. Angina
  22. Anorexia nervosa
  23. Anthrax
  24. Antidepressant withdrawal: Is there such a thing?
  25. Antidepressants and alcohol: What's the concern?
  26. Antidepressants and weight gain: What causes it?
  27. Antidepressants: Can they stop working?
  28. Antidepressants for children and teens
  29. Antidepressants: Side effects
  30. Antidepressants: Selecting one that's right for you
  31. Antidepressants: Which cause the fewest sexual side effects?
  32. Anxiety disorders
  33. Aortic calcification: An early sign of heart valve problems?
  34. Aortic valve regurgitation
  35. Aortic valve stenosis
  36. Aplastic anemia
  37. ARDS
  38. Arteriovenous fistula
  39. Artificial sweeteners: Any effect on blood sugar?
  40. Ascariasis
  41. Aspergillosis
  42. Atrial septal defect (ASD)
  43. Atrioventricular canal defect
  44. Atypical antidepressants
  45. Atypical cells: Are they cancer?
  46. Autoimmune hepatitis
  47. Automated external defibrillators: Do you need an AED?
  48. Base tan? Bad idea
  49. Bedtime routines: Not just for babies
  50. Biopsy procedures
  51. Bipolar disorder and alcoholism: Are they related?
  52. Bipolar disorder
  53. Bipolar in children
  54. Bipolar medications and weight gain
  55. Bipolar treatment: I vs. II
  56. Blastocystis hominis
  57. Infographic: Blood Cancer Awareness
  58. Blood clots during menstruation: A concern?
  59. Blood glucose meters
  60. Blood glucose monitors
  61. Blood sugar levels can fluctuate for many reasons
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  63. Blood tests for heart disease
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  65. Bone and joint problems associated with diabetes
  66. Bone cancer
  67. Bradycardia
  68. Mitral valve overview
  69. Explaining multiple sclerosis
  70. 4 Ways to Prevent Heart Attack
  71. Ebstein Anomaly
  72. Ebstein Anomaly Part Two: Patient Frequently Asked Questions
  73. Fact or Fiction? Debunking Exercise & Nutrition Myths for Preventing Heart Disease and Risk Factors
  74. Giant Cell Myocarditis
  75. Healthy Heart Numbers
  76. Heart disease in women
  77. Heart Failure
  78. How kidneys work
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  87. Screenings of newborns and athletes for genetic heart disease
  88. Video: Septal myectomy and apical myectomy
  89. Sports Cardiology Program
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  91. Treating Pericarditis
  92. When a fainting episode might suggest a LQTS diagnosis
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  95. Brugada syndrome
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  97. Caffeine and depression: Is there a link?
  98. Caffeine: Does it affect blood sugar?
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  100. Can chicken soup cure a cold?
  101. Can vitamins help prevent a heart attack?
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  103. Cancer blood tests
  104. Myths about cancer causes
  105. Infographic: Cancer Clinical Trials Offer Many Benefits
  106. Cancer diagnosis: 11 tips for coping
  107. Cancer diagnosis? Advice for dealing with what comes next
  108. Cancer-related fatigue
  109. Cancer pain: Relief is possible
  110. Cancer risk: What the numbers mean
  111. Cancer surgery
  112. Cancer survival rate
  113. Cancer survivors: Care for your body after treatment
  114. Cancer survivors: Late effects of cancer treatment
  115. Cancer survivors: Managing your emotions after cancer treatment
  116. Cancer survivors: Reconnecting with loved ones after treatment
  117. Cancer treatment decisions: 5 steps to help you decide
  118. Cancer treatment for men: Possible sexual side effects
  119. Cancer treatment for women: Possible sexual side effects
  120. Cancer treatment myths
  121. Cancer Vaccine Research
  122. Cannabis for MS: Can it help treat symptoms?
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  125. Infographic: Cardiac sarcoidosis: A heart under attack
  126. Cardiomyopathy
  127. Caring for a loved one with diabetes
  128. Castleman disease
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  130. Celiac disease: Can gluten be absorbed through the skin?
  131. Celiac disease diet: How do I get enough grains?
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  133. Chemo brain
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  137. Cholera
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  139. Chronic fatigue syndrome
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  147. Coconut oil: Can it cure hypothyroidism?
  148. Coffee after dinner? Make it decaf
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  161. Concussion Telemedicine
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  165. Craving and chewing ice: A sign of anemia?
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  180. Depression in women: Understanding the gender gap
  181. Depression (major depressive disorder)
  182. Depression: Provide support, encouragement
  183. Depression: Supporting a family member or friend
  184. Dermatomyositis
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  186. Diabetes and dental care
  187. Diabetes and depression: Coping with the two conditions
  188. Diabetes and exercise: When to monitor your blood sugar
  189. Diabetes and fasting: Can I fast during Ramadan?
  190. Diabetes and foot care
  191. Diabetes and Heat
  192. Diabetes and menopause
  193. Diabetes and summer: How to beat the heat
  194. Diabetes and travel: Planning is key
  195. Diabetes and electric blankets
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  198. Diabetes diet: Create your healthy-eating plan
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  200. Diabetes foods: Can I substitute honey for sugar?
  201. Diabetes and liver
  202. Diabetes management: Does aspirin therapy prevent heart problems?
  203. Diabetes management: How lifestyle, daily routine affect blood sugar
  204. Diabetes: Eating out
  205. Diabetes nutrition: Sweets
  206. Diabetes prevention: 5 tips for taking control
  207. Diabetes symptoms
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  209. Medications for type 2 diabetes
  210. Using insulin
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  212. Diabetic ketoacidosis
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  230. Endocarditis
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  232. Endometriosis: Risk factor for ovarian cancer?
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  234. Enlarged spleen (splenomegaly)
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  236. Infographic: Esophageal Cancer
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  238. Ewing sarcoma
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  243. Fibromyalgia: Does exercise help or hurt?
  244. Fibromyalgia: Linked to other health problems?
  245. Fibromyalgia pain: Options for coping
  246. Fibromyalgia: Self-care tips
  247. Fibromyalgia and Neurontin
  248. Fibromyalgia or not?
  249. Fingolimod during pregnancy: Is it safe?
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  251. Flu masks
  252. Flu Shot Prevents Heart Attack
  253. Flu shots
  254. Flu shots and heart disease
  255. Flu: When to see a doctor?
  256. Flu vaccine: Safe for people with egg allergy?
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  259. Generalized anxiety disorder
  260. Genetics and Cardiomyopathy
  261. GI Stents
  262. Giardia infection (giardiasis)
  263. Glomerulonephritis
  264. GLP-1 agonists: Diabetes drugs and weight loss
  265. Glycemic index: A helpful tool for diabetes?
  266. Grand mal seizure
  267. Granulomatosis with polyangiitis
  268. Grass-fed beef
  269. Graves' dermopathy: How is it treated?
  270. Graves' disease
  271. H1N1 flu (swine flu)
  272. Hairy cell leukemia
  273. Hangover prevention: Do lighter colored drinks help?
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  275. Hashimoto's disease
  276. Have a cold? Common sense rules
  277. Have a cold? Fight back with humidity
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  287. Heart cancer: Is there such a thing?
  288. Heart disease
  289. Heart disease in women: Understand symptoms and risk factors
  290. Heart failure
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  292. Heart-healthy diet: 8 steps to prevent heart disease
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  294. Heavy periods: Can folic acid help?
  295. Hemochromatosis
  296. Hemolytic uremic syndrome (HUS)
  297. Hemophilia
  298. Hepatitis A
  299. Hepatitis B
  300. Hepatitis C
  301. Hepatitis C: How common is sexual transmission?
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  326. Hypopituitarism
  327. Hypothermia
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  414. Multiple sclerosis: Can it cause seizures?
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