Dermatomyositis (dur-muh-toe-my-uh-SY-tis) is an uncommon inflammatory disease marked by muscle weakness and a distinctive skin rash.

The condition can affect adults and children. In adults, dermatomyositis usually occurs in the late 40s to early 60s. In children, it most often appears between 5 and 15 years of age. Dermatomyositis affects more females than males.

There's no cure for dermatomyositis, but periods of symptom improvement can occur. Treatment can help clear the skin rash and help you regain muscle strength and function.


The signs and symptoms of dermatomyositis can appear suddenly or develop gradually over time. The most common signs and symptoms include:

  • Skin changes. A violet-colored or dusky red rash develops, most commonly on your face and eyelids and on your knuckles, elbows, knees, chest and back. The rash, which can be itchy and painful, is often the first sign of dermatomyositis.
  • Muscle weakness. Progressive muscle weakness involves the muscles closest to the trunk, such as those in your hips, thighs, shoulders, upper arms and neck. The weakness affects both the left and right sides of your body, and tends to gradually worsen.

When to see a doctor

Seek medical attention if you develop muscle weakness or an unexplained rash.


The cause of dermatomyositis is unknown, but the disease has much in common with autoimmune disorders, in which your immune system mistakenly attacks your body tissues.

Genetic and environmental factors also might play a role. Environmental factors could include viral infections, sun exposure, certain medications and smoking.

Risk factors

While anyone can develop dermatomyositis, it is more common in people assigned female at birth. Genetics and environmental factors including viral infections and sun exposure also may increase the risk of developing dermatomyositis.


Possible complications of dermatomyositis include:

  • Difficulty swallowing. If the muscles in your esophagus are affected, you can have problems swallowing, which can cause weight loss and malnutrition.
  • Aspiration pneumonia. Difficulty swallowing can also cause you to breathe food or liquids, including saliva, into your lungs.
  • Breathing problems. If the condition affects your chest muscles, you might have breathing problems, such as shortness of breath.
  • Calcium deposits. These can occur in your muscles, skin and connective tissues as the disease progresses. These deposits are more common in children with dermatomyositis and develop earlier in the course of the disease.

Associated conditions

Dermatomyositis might cause other conditions or put you at higher risk of developing them, including:

  • Raynaud's phenomenon. This condition causes your fingers, toes, cheeks, nose and ears to turn pale when exposed to cold temperatures.
  • Other connective tissue diseases. Other conditions — such as lupus, rheumatoid arthritis, scleroderma and Sjogren's syndrome — can occur with dermatomyositis.
  • Cardiovascular disease. Dermatomyositis can cause heart muscle inflammation. In a small number of people who have dermatomyositis, congestive heart failure and heart rhythm problems develop.
  • Lung disease. Interstitial lung disease can occur with dermatomyositis. Interstitial lung disease refers to a group of disorders that cause scarring of lung tissue, making the lungs stiff and inelastic. Signs include a dry cough and shortness of breath.
  • Cancer. Dermatomyositis in adults has been linked to an increased likelihood of developing cancer, particularly ovarian cancer in women. Risk of cancer appears to level off three years or so after a diagnosis of dermatomyositis.

Mar 04, 2024

  1. Dermatomyositis. Myositis Association of America. https://www.myositis.org/about-myositis/types-of-myositis/dermatomyositis/. Accessed March 20, 2020.
  2. Dermatomyositis information page. National Institute of Neurological Disorders and Stroke. https://www.ninds.nih.gov/Disorders/All-Disorders/Dermatomyositis-Information-Page. Accessed March 20, 2020.
  3. Miller ML, et al. Clinical manifestations of dermatomyositis and polymyositis in adults. https://www.uptodate.com/contents/search. Accessed March 20, 2020.
  4. AskMayoExpert. Dermatomyositis. Mayo Clinic; 2019.
  5. DeWane ME, et al. Dermatomyositis: Clinical features and pathogenesis. Journal of the American Academy of Dermatology. 2020; doi:10.1016/j.jaad.2019.05.105.
  6. Dermatomyositis. Genetics and Rare Diseases Information Center. https://rarediseases.info.nih.gov/diseases/6263/dermatomyositis. Accessed March 20, 2020.
  7. Waldman R, et al. Dermatomyositis: Diagnosis and treatment. Journal of the American Academy of Dermatology. 2020; doi:10.1016/j.jaad..


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