Can thyroid disease affect my mood?
Answer From Juan Brito Campana, M.B.B.S.
Yes, thyroid disease can affect mood. Common thyroid disease symptoms that affect mood include anxiety or depression. In general, the more severe the thyroid disease, the more severe the mood changes.
With overactive thyroid, a condition called hyperthyroidism, mood symptoms may include:
With underactive thyroid, a condition called hypothyroidism, mood symptoms may include:
- Unusual tiredness.
Although thyroid disease can affect mood, it's unusual for those symptoms be the only evidence of thyroid disease. Thyroid disease is associated with many other symptoms such as:
- Weight gain or loss.
- More sensitivity to hot or cold temperatures.
- Bowel movement changes.
- Changes in menstrual cycles.
Treatment for thyroid disease often includes either medicine that lowers the amount of thyroid hormone that the body makes or medicine that replaces missing thyroid hormone. Treatment often improves symptoms caused by thyroid disease, including those that affect mood.
Juan Brito Campana, M.B.B.S.
Dec. 07, 2022
From Mayo Clinic to your inbox
Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health.
ErrorEmail field is required
ErrorInclude a valid email address
To provide you with the most relevant and helpful information, and understand which
information is beneficial, we may combine your email and website usage information with
other information we have about you. If you are a Mayo Clinic patient, this could
include protected health information. If we combine this information with your protected
health information, we will treat all of that information as protected health
information and will only use or disclose that information as set forth in our notice of
privacy practices. You may opt-out of email communications at any time by clicking on
the unsubscribe link in the e-mail.
Thank you for subscribing!
You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox.
Sorry something went wrong with your subscription
Please, try again in a couple of minutes
See more Expert Answers
- Hypothyroidism (underactive). American Thyroid Association. http://www.thyroid.org/hypothyroidism/. Accessed Nov. 15, 2022.
- Hyperthyroidism (overactive). American Thyroid Association. http://www.thyroid.org/hyperthyroidism/. Accessed Nov. 15, 2022.
- Surks MI. Clinical manifestations of hypothyroidism. https://www.uptodate.com/contents/search. Accessed Nov. 15, 2022.
- Bode H, et al. Association of hypothyroidism and clinical depression: A systematic review and meta-analysis. JAMA Psychiatry. 2021; doi:10.1001/jamapsychiatry.2021.2506.
- Ross DS. Overview of the clinical manifestations of hyperthyroidism in adults. https://www.uptodate.com/contents/search. Accessed Nov. 15, 2022.
- Ross DS. Treatment of primary hypothyroidism in adults. https://www.uptodate.com/contents/search. Accessed Nov. 15, 2022.