1. Sept. 21, 2021

    3D-printed models enhance pediatric cerebrovascular education and care

    Mayo Clinic's patient-specific, life-sized models help neurosurgeons to visualize the anatomy of rare pediatric cerebrovascular lesions. The goal is to better prepare surgeons to treat young patients with challenging co[...]

  2. Sept. 21, 2021

    Clues for defining the diagnosis and course of demyelinating diseases

    A Mayo Clinic study identified clear differences in the resolution of lesions in three demyelinating diseases. The findings shed light on the development of long-term disability in MS.

  3. Aug. 20, 2021

    Pituitary tumors: Patient-centered care facilitates strong outcomes

    A Mayo Clinic study documented fewer surgical complications and shorter hospital stays for individuals having pituitary tumor surgery at Mayo compared with results from a multicenter study.

  4. Aug. 20, 2021

    Combining PET scans and 7-tesla MRI to pinpoint subtle epileptogenic lesions

    Overlays of PET images and 7-tesla MRI can help identify candidates for surgery among the one-third of individuals with epilepsy who have medically refractory seizures.

  5. Aug. 20, 2021

    Genetic tumor testing for more-precise treatment of glioma

    Mayo Clinic's cerebral spinal fluid biomarker tests use next-generation sequencing to evaluate mutations and rearrangements in 187 genes, for optimal tumor management.

  6. Aug. 20, 2021

    Alzheimer's biomarker testing: Boosting diagnostic accuracy so that patients can plan for the future

    Cerebral spinal fluid (CSF) biomarkers can predict the results of PET scan findings in people with mild cognitive impairment or dementia. Test results are available quickly.

  7. July 21, 2021

    Vestibular schwannoma: Meeting each patient's needs through shared decision-making

    Mayo Clinic diagnoses and treats nearly 800 people a year with vestibular schwannomas. The treatment team has extensive experience in microsurgery, radiosurgery and observation of these intracranial tumors.

  8. July 21, 2021

    Carotid plaque imaging: Updating the management of atherosclerotic disease

    Mayo Clinic's robust imaging protocol can detect intraplaque hemorrhage and other signs of instability — information key to guiding the diagnosis and prevention of strokes.

  9. July 21, 2021

    Chemotherapy-induced cognitive impairment: A potential preventive strategy

    Mice pre-treated with nicotinamide mononucleotide before cisplatin therapy performed better on subsequent learning and memory tests than did mice that weren't pre-treated.

  10. July 21, 2021

    Telestroke: World-class expertise 24/7 for patients in remote areas

    Mayo Clinic's expanding telestroke network has morbidity and mortality outcomes that don't differ statistically from outcomes for patients treated at a Mayo stroke center.

  11. June 19, 2021

    Focused ultrasound: Incisionless epilepsy treatment

    Mayo Clinic is participating in an invitation-only clinical trial of a new thermoablative treatment for medically refractory focal epilepsy. The new approach can treat seizure-origin sites in deep brain areas.

  12. June 19, 2021

    Prenatal repair can improve hindbrain herniation

    About 90% of prenatal myelomeningocele repairs performed at Mayo Clinic reverse brain malformations before birth. The procedure requires multidisciplinary neurological, pediatric and radiologic expertise.

  13. June 19, 2021

    New myelography protocol helps localize cerebrospinal fluid leaks

    Mayo Clinic's use of state-of-the-art digital subtraction myelography paves the way for definitive treatment of debilitating cerebrospinal fluid leaks.

  14. June 19, 2021

    Neuromyelitis optica: New therapies offer hope

    Mayo Clinic's experience and expertise with neuromyelitis optica spectrum disorder (NMOSD), a rare inflammatory disorder, facilitate decisions about optimal treatment choices for individual patients.

  15. May 21, 2021

    Precise and personalized guidance for epilepsy's complex decisions

    Mayo Clinic specialists are committed to educating individuals about their many nonmedical treatment options.

  16. May 21, 2021

    Comprehensive mapping of cognitive functions during awake surgery

    The innovative technology provides detailed and efficient information in real time to avoid damage to eloquent tissue in epilepsy and tumor surgeries.

  17. May 21, 2021

    Building the knowledge for skull base surgery

    Mayo Clinic clinician-researchers are learning more about cranial anatomy. Their work paves the way for the development of new surgical techniques for skull base disease.

  18. May 21, 2021

    Moyamoya: New protocol for managing a complex disease

    Critical imaging tests can be performed in a single session and without ionizing radiation.

  19. April 15, 2021

    Innovative treatment eases hundreds of daily seizures

    The patient was the first at Mayo Clinic to have the noninvasive therapy as a treatment for seizures.

  20. April 15, 2021

    Novel endovascular therapy for CSF-venous fistulas

    Mayo Clinic's new approach provides an alternative to invasive spinal surgery.

  21. April 15, 2021

    Elucidating a rare pituitary cancer

    A Mayo Clinic study describes the challenges of diagnosing individuals with this cancer and outlines treatment options.

  22. March 27, 2021

    Point-of-care additive manufacturing provides complex scoliosis models

    Mayo Clinic radiologists and neurosurgeons collaborate to rapidly create 3D-printed anatomic models.

  23. March 27, 2021

    Spondylolisthesis: Individualized approach for optimal outcomes

    Mayo Clinic spinal surgeons use a wide range of approaches to treat patients with congenital and degenerative spondylolisthesis.

  24. March 20, 2021

    Retinoblastoma: Specialized neuroradiology for optimal care

    Mayo Clinic's experienced specialists work to preserve the child's life, eye and sight.

  25. March 20, 2021

    New technology for the treatment of pediatric epilepsy

    Mayo Clinic Children's Center has a multispecialty team devoted to epilepsy care. New technology and clinical trials offer options even for rare syndromes.

  26. March 13, 2021

    Robotic systems can perform simple ICU care tasks

    Automation can reduce health risks for nurses and free them to focus on more-critical aspects of care.

  27. March 13, 2021

    NF2 Clinic: Proactive, coordinated multidisciplinary care

    Providers in 12 specialties collaborate to provide timely diagnosis and treatment for teenagers and adults with neurofibromatosis 2 (NF2).

  28. Feb. 15, 2021

    Researchers identify gene implicated in neuroblastoma, a childhood cancer

    ROCHESTER, Minn. ? A new study by Mayo Clinic researchers has identified that a chromosome instability gene, USP24, is frequently missing in pediatric patients with neuroblastoma, an aggressive form of childhood [...]

  29. Jan. 23, 2021

    Telemedicine offers benefits in the COVID-19 era and beyond

    Mayo Clinic's expanded use of telemedicine is likely to continue after the current pandemic eases.

  30. Jan. 23, 2021

    Robot-assisted spinal surgery shows promising initial results

    None of the 402 screws implanted in Mayo Clinic's study of robot-assisted spinal surgery required postoperative revision.

  31. Jan. 23, 2021

    Longitudinal study maps the transition to Alzheimer's disease

    A Mayo Clinic study underway since 1994 is providing key insights, including behavioral changes before symptoms start.

  32. Jan. 23, 2021

    Burr hole approach offers minimally invasive option for resecting brain lesions

    Select brain lesions can be surgically removed through a 14-millimeter burr hole.

  33. Dec. 31, 2020

    Research highlights in Neurology and Neurosurgery — May 2020

    Mayo Clinic Neurology and Neurosurgery studies address the risk of carotid artery injury, clinical diagnosis of progressive supranuclear palsy and characterization of amphiphysin-IgG autoimmunity.

  34. Dec. 31, 2020

    McArdle sign can provide reliable clinical detection of MS

    McArdle sign — a clinical phenomenon in which neck flexion induces rapid, reversible weakness — is also moderately sensitive for a diagnosis of multiple sclerosis compared with other myelopathy conditions.

  35. Dec. 31, 2020

    Leading NIH's Lewy body dementia initiative

    A National Institutes of Health (NIH) initiative studies the proteins involved in Lewy body dementia to better characterize disease progression and identify potential therapeutic targets.

  36. Nov. 17, 2020

    Women's Wellness: Earlier menopause, fewer pregnancies linked to early onset of progressive MS

    Women who experience early menopause may be more likely to face an early onset of progressive multiple sclerosis (MS). That is the finding of a Mayo Clinic study recently published in Brain Communications. Researchers also[...]

  37. Nov. 02, 2020

    3D Brain Model Advances Alzheimer's Research at Mayo Clinic

    The model system allows stem cells to grow in three dimensions, ensuring researchers can study amyloid-beta plaques and tau tangles associated with neurodegeneration together.

  38. Oct. 03, 2020

    Favorable long-term outcomes in pediatric AVM interventions

    Intervention is critical in maximizing the outcomes of pediatric arteriovenous malformations (AVMs). Mayo Clinic researchers have found that favorable functional outlooks for pediatric patients with AVMs can persist for[...]

  39. Oct. 02, 2020

    Ventricular volume: Clinical utility for assessing current and future cognition and gait

    Mayo Clinic researchers have found that ventricular volume measures are clinically more useful than the Evans index ratio in evaluating a patient's current and future cognition and gait.

  40. Oct. 02, 2020

    Spinal vascular malformations: Early interventions and importance of proper diagnosis

    Mayo Clinic's depth of expertise allows for detailed diagnosis of spinal vascular malformations and covers the complexity of these conditions, enabling timely, precise diagnosis that allows for optimal individualized tr[...]

  41. Oct. 02, 2020

    Looking at burnout and attrition in neurology: Expanding the gender gap?

    Studies suggest burnout may be 20% to 60% higher among women than men. In an article published in Neurology, Mayo Clinic physicians and researchers focused on burnout, attrition and the expanding gender gap.

  42. Oct. 02, 2020

    Epilepsy: The next generation of neurostimulation therapies

    Translating neurostimulation research and innovations into patient care is the overarching goal of Kai J. Miller, M.D., Ph.D., and Dora Hermes, Ph.D., both Mayo Clinic physicians and researchers.

  43. Oct. 02, 2020

    Elucidating the structural diversity of tauopathies

    Using a new method, Mayo Clinic researchers identify post-translational modifications as playing an important role in mediating the distinct structures of tau fibrils in corticobasal degeneration and Alzheimer's disease[...]

  44. Oct. 02, 2020

    Neurological simulations: The next generation

    Simulation of neurological disease is difficult. Mayo Clinic has advanced its simulation training capabilities and envisions a future where specific learning objectives are matched to simulation modality and are best ac[...]

  45. Oct. 02, 2020

    Post-traumatic headache: Clinical trial seeks predictors and therapies

    Nearly 40% of patients who develop acute post-traumatic headache experience persistent headaches. Researchers are conducting a major study to identify mechanisms and predictors of persistent post-traumatic headache caus[...]

  46. Aug. 14, 2020

    Glioblastoma: Seeking personalized care through radiomics

    Mayo Clinic is using radiomics to learn more about individuals' responses to glioblastoma treatment. Tumor volume can affect an individual's response to chemotherapy. Differences in the molecular mechanisms of tumors in[...]

  47. Aug. 04, 2020

    Cervical myelopathy: Discoveries paving the way to better care

    Cervical myelopathy symptoms often recur after surgery, due to suboptimal positioning of the spinal cord during the procedure. Mayo Clinic is learning more about the stress placed on the spinal cord, to determine the be[...]

  48. Aug. 04, 2020

    Pediatric brain tumors: Rapid and focused care

    Patients referred to Mayo Clinic for pediatric brain tumor can often be seen the next day. A team of specialists works together, drawing on Mayo's broad expertise in neuro-oncology.

  49. June 27, 2020

    Moyamoya: Specialized care for a rare cerebrovascular disease

    Mayo Clinic's moyamoya clinic provides comprehensive care for this rare cerebrovascular disease. Within a single clinic visit, patients can see a multidisciplinary care team and receive a treatment plan.

  50. June 27, 2020

    Stem cell treatment after spinal cord injury: The next steps

    Mayo Clinic's CELLTOP trial involves intrathecal injections of autologous adipose-derived stem cells. Mayo's investigations focus on how stem cells can potentially reverse the microenvironmental changes that inhibit axo[...]

  51. June 27, 2020

    Glioblastoma extracellular vesicles: Targeting the ill effects, using the good

    The mechanisms by which glioblastoma-derived extracellular vesicles promote tumor growth appear to be more complicated than previously thought. Mayo Clinic is working to exploit certain factors of extracellular vesicles[...]

  52. June 13, 2020

    Robot-assisted brain surgery: Innovating to improve patient care

    Alfredo Quinones-Hinojosa, M.D., chair of Neurosurgery at Mayo Clinic in Jacksonville, Florida, discusses Mayo's efforts to develop robotic technology for performing brain surgery.

  53. June 13, 2020

    AVMs: Advanced technology and expertise for complex pathology

    Mayo Clinic uses 3D modeling software and augmented reality visualization to guide decision-making for treatment of arteriovenous malformations. Treatment options include microsurgical resection, endovascular embolizati[...]

  54. June 13, 2020

    New approaches to immunotherapy for glioblastoma

    Mayo Clinic is advancing new applications of immunotherapy for glioblastoma, with a focus on more-potent and combination therapies for optimal effectiveness.

  55. May 01, 2020

    Mayo Clinic expert discusses potential neurological effects of COVID-19

    SARS-CoV-2, the virus that causes COVID-19, can take a severe toll on the respiratory system. However, recent research suggests that the virus may also infect the nervous system. A study of patients with COVID-19 out of Wu[...]

  56. April 11, 2020

    Research focus: Spina bifida surgery before birth restores brain structure

    Mayo Clinic researchers have discovered that the benefit from spina bifida repair performed on a fetus in the womb works beyond the spine to improve the brain structure.

  57. March 03, 2020

    Gene variants may increase susceptibility to accumulate Alzheimer's protein tau, study shows

    ROCHESTER, Minn. -- The toxic protein tau is a key biological feature in the brains of people with Alzheimer's disease. Yet the factors that make people susceptible or resistant to tau accumulation are not well-understood.[...]

  58. Feb. 28, 2020

    Autoimmune neurology: Evolving care for immune-inflammatory diseases of the CNS

    Alfonso (Sebastian) S. Lopez Chiriboga, M.D., and Iris (Vanessa) V. Marin Collazo, M.D., discuss autoimmune neurology, one of neurology's most rapidly evolving subspecialties.

  59. Feb. 28, 2020

    Enterprisewide expertise for spinal oncology care

    Mayo's spinal oncology specialists may employ proton beam therapy, carbon fiber implants or surgical alternatives ― such as decompression, stabilization, ablation technologies or cement augmentation ― to meet each patie[...]

  60. Jan. 31, 2020

    Multiple options for the treatment of children with epilepsy

    At Mayo Clinic Children's Center, research and clinical teams function seamlessly to provide novel therapies to treat seizures and preserve brain function for pediatric patients with epilepsy.

  61. Jan. 10, 2020

    Mayo Clinic research discovers a molecular switch for repairing central nervous system disorders

    ROCHESTER, Minn. -- A molecular switch has the ability to turn on a substance in animals that repairs neurological damage in disorders such as multiple sclerosis (MS), Mayo Clinic researchers discovered. The early research[...]

  62. Dec. 21, 2019

    Nanotechnology: Potential options for glioblastoma treatment

    Mayo Clinic is developing ways to use nanoparticles to modify adipose-derived mesenchymal stem cells to secrete anti-tumor proteins. The therapy can then be delivered at the time of tumor resection.

  63. Dec. 21, 2019

    Whole-patient epilepsy care: Uniting technology and psychosocial expertise

    Mayo Clinic's patient-centered care combines sophisticated imaging and surgical techniques with a multidisciplinary focus encompassing the psychosocial problems associated with epilepsy.

  64. Dec. 10, 2019

    Mayo Clinic calls out need for aggressive glioblastoma treatment

    Aggressive cellular therapy, new drugs, surgery & clinical trials needed for glioblastoma brain tumor survival: Mayo Clinic Forefront cancer magazine.

  65. Dec. 10, 2019

    Scientists find autoimmune disease related to testicular cancer

    Scientists urge screening for paraneoplastic encephalitis autoimmune disease in patients with testicular cancer: Mayo Clinic Forefront cancer magazine.

  66. Nov. 27, 2019

    Case report: Stem cells a step toward improving motor, sensory function after spinal cord injury

    ROCHESTER, Minn. -- Stem cells derived from a patient's own fat offer a step toward improving -- not just stabilizing -- motor and sensory function of people with spinal cord injuries, according to early research from Mayo[...]

  67. Nov. 27, 2019

    Mayo Clinic research is a step toward hope for spinal cord injuries

    In a study of mesenchymal stem cell treatment for spinal cord injury, stem cell intervention following surgery plus physical and occupational therapy restored some function in a patient.

  68. Nov. 18, 2019

    Mayo Clinic in Arizona named Center of Excellence for Enhanced Recovery After Surgery

    PHOENIX -- Mayo Clinic in Arizona has been recognized as a Center of Excellence for Enhanced Recovery After Surgery (ERAS), the second medical center in the U.S. to earn that distinction. Enhanced Recovery After Surgery ai[...]

  69. Nov. 15, 2019

    Cellular “Cleaners” More Active in Quiet Brains

    Researchers found that in mice, microglia (immune cells of the central nervous system) are more active when the brain is quiet than when it is awake, due to norepinephrine signaling.

  70. Nov. 09, 2019

    Fetoscopic repair of myelomeningocele: A minimally invasive option

    Fetoscopic repair of myelomeningocele can provide surgical outcomes for the fetus that are similar to those of open surgery while lessening the risk of preterm birth.

  71. Nov. 01, 2019

    Refining CT perfusion imaging for optimal stroke care

    Mayo Clinic specialists fine-tune quantifiable CT perfusion imaging to widen the treatment window for acute ischemic stroke and optimize outcomes in carefully selected patients.

  72. Oct. 11, 2019

    Glioma Forecast? Excellent Chance for Better Weather says Researcher

    Kristin R. Swanson, Ph.D., uses mathematical modeling to document glioblastoma texture, density, direction of growth and rate of invasion ― and predict the best treatment for each patient.

  73. Sept. 05, 2019

    Specialized expertise for spinal deformity surgery

    The wide range of spinal deformity treated at Mayo Clinic encompasses all forms of scoliosis and kyphosis, high-grade spondylolisthesis, and cervical spine and post-laminectomy deformity, as well as revision surgeries.

  74. Sept. 05, 2019

    New clue for earlier diagnosis of spinal dural AVF

    Mayo Clinic has identified a unique radiographic finding that facilitates earlier diagnosis of spinal dural arteriovenous fistulas (dAVFs), paving the way to improved treatment outcomes.

  75. Sept. 05, 2019

    Robot-guided technology to enhance spinal surgery

    Mayo specialists employ robotic technology for surgery in the thoracic and lumbar spine. The system can be applied to small, minimally invasive procedures and more-complex open surgeries for oncologic or spinal deformit[...]

  76. Aug. 30, 2019

    Quantifying neuroimaging: A revolution in patient care

    Mayo Clinic specialists apply innovative neuroimaging techniques and quantifiable machine learning methodology for individualized prognosis and treatment of brain tumors and epilepsy.

  77. Aug. 30, 2019

    Research highlights in Neurology and Neurosurgery ― September 2019

    Studies address checkpoint inhibitors and neurological immune-related adverse events, a tissue biomarker for Parkinson's disease, glioma-related seizures and tumor molecular markers, and imaging factors related to cogni[...]

  78. Aug. 30, 2019

    Preserving vision, easing headaches: Timely multidisciplinary care for idiopathic intracranial hypertension

    At Mayo Clinic's cerebral spinal fluid dynamics clinic, patients can see a neurologist and neuro-ophthalmologist, have diagnostic testing, and see a neurosurgeon, if needed, within a few days.

  79. Aug. 30, 2019

    Objective testing for sports-related concussion

    The Mayo Clinic Concussion Check Protocol can be used by parents or other adults on the sidelines to quickly assess whether a young athlete should be removed from play.

  80. Aug. 30, 2019

    Idiopathic transverse myelopathy: Pinpointing the cause

    A review of idiopathic transverse myelitis cases referred to Mayo Clinic from 2010 to 2015 confirms that in nearly 70% of cases, Mayo specialists supplied an accurate diagnosis.

  81. Aug. 30, 2019

    Innovative options for medically refractory epilepsy

    All three Mayo Clinic campuses offer intensive neurodiagnostic monitoring and extensive medical, neuropsychological and psychosocial treatment for medically refractory epilepsy. Neurologist Anthony L. Ritaccio, M.D., di[...]

  82. Aug. 13, 2019

    The BeST approach to functional movement disorders

    Mayo Clinic physiatrist Jeffrey M. Thompson, M.D., discusses the behavioral shaping therapy (BeST) approach to functional movement disorders in this episode of Simply PM&R Podcast.

  83. Aug. 06, 2019

    Researching stem cell therapy for hemorrhagic stroke

    A review of current studies confirms that mesenchymal stem cells (MSCs) are safe and tolerable in patients with hemorrhagic stroke and continued research is warranted.

  84. July 30, 2019

    What's new in motor recovery research and helping patients stay active with spinal cord injuries

    Mayo Clinic physiatrist Kristin L. Garlanger, D.O., describes traumatic and nontraumatic spinal cord injuries and research advances and interventions in this Simply PM&R Podcast episode.

  85. July 16, 2019

    Study identifies clinical phenotype, visual outcomes of MOG-IgG antibody optic neuritis

    Research supports that MOG-IgG positivity should be suspected if optic disk edema is moderate to severe at onset or if MRI shows optic nerve sheath involvement.

  86. July 13, 2019

    BeST program treatment model focuses on motor retraining for functional movement disorders

    Mayo Clinic physiatrist Jeffrey M. Thompson, M.D., discusses the behavioral shaping therapy (BeST) approach to functional movement disorders in this episode of Simply PM&R Podcast.

  87. June 25, 2019

    Headache disorders: Subspecialized, compassionate care

    Headache neurologist Jonathan H. Smith, M.D., answers questions about subspecialized management of headache disorders.

  88. June 25, 2019

    Onco-epilepsy: Simultaneous management of tumor and seizures

    Mayo's multidisciplinary, proactive approach facilitates the safe removal of noneloquent tissue that is potentially epileptogenic, to manage tumor and epilepsy at the same time.

  89. June 25, 2019

    Halting the circle: Comprehensive neurogenetics test panels

    Mayo Clinic's use of comprehensive next-generation sequencing panels for the diagnosis of neurogenetic disorders covers the expanding genotype-phenotype complexity of these conditions, facilitating timely, accurate diag[...]

  90. June 25, 2019

    Cavernous malformations: 7-tesla MRI enhances expertise

    Mayo specialists use 7-tesla MRI advanced imaging technology to aid diagnosis and decisions about whether cavernous malformations should be surgically removed to prevent bleeding.

  91. June 25, 2019

    Research highlights in Neurology and Neurosurgery ― May 2019

    Studies address cerebral microbleeds and amyloid burden, treatment outcomes for spinal cord low-grade gliomas, and unplanned returns to the operating room following neurosurgery.

  92. April 26, 2019

    Coordinated management of young-onset Parkinson's disease

    A new clinic addresses the needs of people who are diagnosed with Parkinson's disease while still working, raising children and living a more active lifestyle than people diagnosed in their late 60s.

  93. April 26, 2019

    Investigating autoinflammatory epileptic encephalopathies in children

    Mayo specialists answer questions about pediatric epileptic encephalopathies caused by neuroinflammation in the absence of antibodies, which can present with signs and symptoms similar to those of autoimmune epilepsy.

  94. April 26, 2019

    Melding technology and expertise for optimal spinal surgery

    Spinal surgery at Mayo Clinic combines advanced technology with the personalized expertise of a multidisciplinary treatment team to deliver optimal outcomes for patients with spinal conditions.

  95. March 01, 2019

    Research highlights in Neurology and Neurosurgery – March 2019

    Studies address atypical presentations of central nervous system tumors, APOE e4 and Lewy bodies pathology, and obstructive sleep apnea related to unexpected death in people with epilepsy.

  96. March 01, 2019

    Neurofibromatosis Clinic: A team for lifelong care

    At Mayo Clinic, multidisciplinary teams of specialists collaborate to manage neurofibromatosis types 1 and 2 (NF1 and NF2) in children and adults.

  97. March 01, 2019

    Vascular pathologies and Alzheimer's disease: Probing genetic pathways

    With funding from the National Institutes of Health M2OVE-AD Consortium, Mayo researchers investigate genetic pathways that may contribute to both vascular pathologies and Alzheimer's disease.

  98. March 01, 2019

    Endoscopic skull base surgery: The advantages of Mayo's team approach

    Mayo Clinic specialists have extensive experience with endoscopic skull base surgery for the treatment of pituitary tumors, meningiomas, clival tumors, chordomas and craniopharyngiomas.

  99. Jan. 21, 2019

    Halting the Wheel of Misfortune: ‘A New Era’ in Migraine Care

    New understanding of the biology underlying migraine and the development of mechanism-based, disease-specific therapies developed specifically to treat and prevent the disorder are changing migraine care.

  100. Jan. 11, 2019

    Advances in pediatric refractory epilepsy

    Quantitative morphometric MRI analysis provides voxel-by-voxel comparisons between patient MRIs and a normative pediatric sample to detect the subtle signs of focal cortical dysplasia in children and guide decisions abo[...]

  101. Jan. 11, 2019

    Team approach for optimal tumor care

    Mayo's pediatric brain tumor laboratory has screened thousands of promising drugs in numerous cancer cell lines, uncovering pathways such as signal transducer and activator of transcription 3 (STAT3) proteins and Aurora[...]

  102. Jan. 11, 2019

    Pediatric care in Arizona and Florida

    Mayo Clinic collaborates with Phoenix Children's Hospital in Arizona and Wolfson Children's Hospital in Florida to provide certain pediatric neurological and neurosurgical services. The collaborations offer pediatric pa[...]

  103. Jan. 11, 2019

    Neonatal brachial plexus injuries: An integrated approach

    Mayo Clinic's multidisciplinary team approach to neonatal brachial plexus surgery allows for surgical reconstruction tailored to the individual patient's needs — nerve surgery, tendon transfers and shoulder-to-han[...]

  104. Dec. 11, 2018

    7-Tesla MRI: Pioneering use for patient care

    Clinical use of 7-Tesla MRI enhances Mayo Clinic's ability to manage epilepsy, certain brain and peripheral nerve tumors, and other neurological disorders.

  105. Dec. 11, 2018

    Neurosurgery registry for continuous improvement of care and quality of life

    Mayo's neurosurgery registry improves patient safety and outcomes by detailing surgical and patient-reported outcomes for all neurosurgical procedures performed at Mayo Clinic. The registry augments efforts to collect s[...]

  106. Dec. 11, 2018

    CREST-2 update: Enrolling patients for optimal care

    Mayo neurologist Kevin M. Barrett, M.D., answers questions about the Carotid Revascularization Endarterectomy Versus Stenting Trial 2 (CREST-2), a multicenter, randomized study that compares methods to identify an optim[...]

  107. Dec. 11, 2018

    Spinal oncology: Multidisciplinary approach for complex care

    Mayo Clinic provides multidisciplinary, subspecialized expertise to manage care for people with even the most complex intradural and vertebral tumors, including both primary and metastatic disease.

  108. Nov. 12, 2018

    Neuro-Oncology Testing [A Test in Focus]

    Mayo Clinic Laboratories offers a neuro-oncology expanded gene panel (NONCP) and chromosomal microarray testing (CMAPT) to provide a clear picture of the diagnosis, prognosis and treatment options for patients in neuro-[...]

  109. Nov. 03, 2018

    Cavernous angiomas: Infrastructure for future drug trials

    Mayo Clinic participates in the multicenter Study of Trial Readiness in Cavernous Angiomas with Symptomatic Hemorrhage, intended to construct workable models for future therapeutic trials for treatment of the rare cereb[...]

  110. Nov. 03, 2018

    Beyond the status quo: Technical advances in neurosurgery

    Innovations in technology applications, imaging techniques and minimally invasive surgical approaches, plus a thorough assessment of the impact on patient care, maximize both safety and outcomes for patients at Mayo Cli[...]

  111. Oct. 30, 2018

    New directions in the study of Alzheimer’s disease

    Researchers in Jacksonville, Florida, study immune system pathways that contribute to Alzheimer's disease, protein variants that lead to different types of Alzheimer's disease, and biological factors that protect people[...]

  112. Sept. 12, 2018

    Minimally invasive surgery for craniosynostosis

    Minimally invasive surgery can be performed earlier than open surgery for infants with craniosynostosis — with the same outcomes. Babies with multiple suture or syndromic conditions may also benefit.

  113. May 22, 2018

    Novel MOG assay aids diagnosis of demyelinating diseases

    Mayo Clinic has developed the first test available in the United States to identify the myelin oligodendrocyte glycoprotein (MOG) antibody in patients' blood. The MOG antibody can distinguish a spectrum of autoimmune de[...]

  114. May 22, 2018

    Subspecialized neuro-ophthalmology care

    Mayo neuro-ophthalmologists work closely with neurologists and neurosurgeons to treat people with any problems involving sight or eye movement that arise from the nervous system, including migraine, stroke or multiple s[...]

  115. May 19, 2018

    AVM: Multimodal approach for individualized treatment

    Mayo specialists' multimodal approach to the treatment of arteriovenous malformations (AVMs) encompasses microsurgical resection, endovascular embolization, stereotactic radiosurgery and awake surgery, as well as watchf[...]

  116. May 19, 2018

    Minimally invasive brain surgery: Safer treatment of deep-seated lesions

    Minimally invasive surgery using a tubular retractor system can be an option for selected patients with subcortical high-grade glioma, metastatic brain tumors or vascular lesions.

  117. April 27, 2018

    Groundbreaking trial of stem cell treatment for intracerebral hemorrhage

    Mayo Clinic is conducting a clinical trial of stem cell treatment for intracerebral hemorrhage (ICH). Investigators hope that results will lead to therapies that provide neuronal protection or recovery for people with I[...]

  118. April 27, 2018

    Clinical trial of stem cell therapy for traumatic spinal cord injury

    Mayo Clinic is enrolling patients in a clinical trial of adipose stem cell treatment for spinal cord injury caused by trauma. Participants will receive intrathecal injections of adipose-derived mesenchymal stem cells. N[...]

  119. April 27, 2018

    Advances in endoscopic skull base surgery

    Mayo specialists employ image guidance and intraoperative CT, 3-D endoscopy, simulations that integrate endoscopic surgery and proton beam therapy, and 3-D models and holography for pre-surgical planning to treat pituit[...]

  120. Feb. 15, 2018

    Minimally invasive options for medically refractory epilepsy

    The Stereotactic Laser Ablation for Temporal Lobe Epilepsy (SLATE) clinical trial tests the efficacy of MRI-guided laser ablation for mesial temporal sclerosis. The approach allows patients to avoid open temporal lobect[...]

  121. Jan. 30, 2018

    Timely ALS care in Florida

    At Mayo Clinic's campus in Jacksonville, Florida, patients with amyotrophic lateral sclerosis (ALS) benefit from a holistic approach to care, including coordinated appointments that ensure prompt intervention, remote fo[...]

  122. Jan. 20, 2018

    Regenerative medicine: Potential to improve life after brain tumor treatment

    Studies suggest that radiation used to treat brain tumors accelerates aging-like changes in the brain. Mayo researchers are working to minimize the amount of brain exposed to radiation and develop strategies to help rej[...]

  123. Dec. 29, 2017

    Individualized approach for complex intracranial aneurysms

    Mayo neurovascular specialists manage complex intracranial aneurysms successfully — with low morbidity and low mortality — through the use of treatment modalities such as extracranial to intracranial bypass,[...]

  124. Dec. 29, 2017

    Objective criteria for migraine

    Mayo researchers are using brain MRI to develop objective biomarkers for the classification of migraine. Their goal is to identify objective differences among people with migraine and other headache types that predict t[...]

  125. Dec. 05, 2017

    Mayo Clinic researchers show how neuroblastoma spreads

    Mayo Clinic researchers show how neuroblastoma spreads: Mayo Clinic Forefront.

  126. Nov. 22, 2017

    The Fish Farm

    Zebrafish have become the model of choice in many medical laboratories. They breed more prolifically and hold more animals per research footprint compared with other vertebrates, and can be very resource-friendly.

  127. Oct. 24, 2017

    Awake craniotomy for tumor resection in motor and sensory tissue

    Mayo neurosurgeons have successfully expanded their use of awake craniotomy from the removal of tumors in the cortical speech area of the brain to areas of eloquent motor and sensory tissue.

  128. Oct. 24, 2017

    Intraneural perineuriomas: Common cause identified

    Researchers have identified a common cause for rare intraneural perineuriomas and an unexpected shared pathogenesis with intracranial meningiomas. The finding indicates a pathway for potential treatment.

  129. Oct. 13, 2017

    Deep brain stimulation for movement disorders

    Recent findings suggest that subthalamic nucleus deep brain stimulation (DBS) provokes dopamine release and that its concentration varies depending on the site being stimulated. DBS of the subthalamic nucleus has been s[...]

  130. Aug. 30, 2017

    Electromyography: Innovation and quality nationwide

    Mayo's board-certified electrophysiologists and technicians complete nerve conduction studies and needle examination of common and uncommon nerves and muscles — plus specialized tests such as diaphragmatic and per[...]

  131. Aug. 30, 2017

    Tissue biopsy for identifying early Parkinson's

    Research indicates that submandibular gland needle biopsies can identify Lewy type alpha-synucleinopathy in people with Parkinson's disease of less than five years' duration.

  132. Aug. 25, 2017

    Dementia Mysteries Untangled

    Frontotemporal dementia is the second-leading cause of presenile neurodegeneration in the U.S. Researchers at Mayo Clinic in Jacksonville, Florida, conduct molecular genetic analyses that help unravel the steps of neuro[...]

  133. Aug. 21, 2017

    New Alzheimer's gene pathway discovered

    Mayo research confirms that the clusterin gene dictates whether amyloid accumulates in the functional tissue versus the blood vessels of the brain. In many patients with Alzheimer's disease, amyloid accumulates[...]

  134. June 27, 2017

    Moyamoya disease: New approaches in Arizona

    Moyamoya disease can cause recurring transient ischemic attacks, strokes, seizures and cognitive deterioration, especially in young people. Mayo neurosurgeons are pioneering new approaches to treatment, to improve cereb[...]

  135. June 27, 2017

    Posterior fossa parenchymal biopsy: Yield and safety

    A study of posterior fossa biopsies performed at Mayo Clinic from 1996 to 2009 indicates that, in carefully selected patients with inflammatory brain diseases, the posterior fossa is appropriate to cerebellar and brains[...]

  136. June 13, 2017

    Meet the investigator: Kristin R. Swanson, Ph.D.

    Kristin R. Swanson, Ph.D., of Mayo Clinic, discusses her brain cancer research: Mayo Clinic Forefront.

  137. April 28, 2017

    Subthreshold cortical stimulation for epilepsy

    Mayo neurologists have successfully suppressed seizures in patients with drug-resistant focal epilepsy. In a 2016 study, 10 of 13 patients reported improvement for epilepsy severity and quality of life after chronic sub[...]

  138. April 21, 2017

    Steering Cells through the Brain

    Researchers have ascertained how neuroblasts in the fetal brain migrate from the subventricular zone to the olfactory bulb, where they fully differentiate into neurons: A key set of molecular cues guide the migration.

  139. Feb. 22, 2017

    Strategy to prevent chemotherapy-induced neuropathy

    Mesenchymal stem cells act as therapy for nervous system diseases by carrying extracellular products across the blood-brain barrier in patients with amyotrophic lateral sclerosis. The stem cells may also be used to deli[...]

  140. Feb. 22, 2017

    Novel biomarker for a treatable meningoencephalomyelitis

    The antibody, which targets glial fibrillary acidic protein (GFAP), has only been found in patients with autoimmune meningoencephalomyelitis, a rapidly progressive neurological disorder. Mayo's clinical test for the GFA[...]

  141. Feb. 22, 2017

    Targeted DNA sequencing for neurological conditions

    The neurology genomics clinic provides patients with complex neurological conditions with access to research, testing, diagnosis and treatment, plus recommended screening and counseling for family members.

  142. Dec. 29, 2016

    Clinical trials of cannabidiol for epilepsy

    Data from clinical trials of Epidiolex, a cannabidiol (CBD) treatment, for children with Dravet syndrome show that seizures were reduced by 39 percent in children treated with CBD versus only 16 percent in the placebo g[...]

  143. Dec. 18, 2016

    Stereotactic radiosurgery is best for some brain tumors

    Mayo Clinic Forefront magazine: Shift in practice may reserve whole-brain radiation for patients with extensive disease.

  144. Nov. 18, 2016

    Finding new treatments for high-grade pediatric brain tumors

    Brain and central nervous system tumors now represent the most common cause of cancer-related death in children. New information about the molecular diversity of these tumors points the way toward targeted therapies tai[...]

  145. Oct. 28, 2016

    Proton beam therapy in Minnesota and Arizona

    Proton beam therapy targets tumors more precisely than photon radiation, limiting damage to surrounding healthy organs and tissue and offering the possibility of using higher doses of radiation for more-beneficial outco[...]

  146. Oct. 28, 2016

    Lateral and percutaneous interbody fusions

    Minimally invasive procedures for interbody fusion, including lateral interbody fusion and percutaneous interbody fusion, can offer patients minimal blood loss, less pain, shorter hospitalization and quicker recovery.

  147. Oct. 28, 2016

    Elucidating lysosomal diseases

    Neurological findings with or without systemic changes in the skin, viscera, heart or bones may indicate lysosomal disease. Mayo researchers are conducting next-generation sequencing of the genes of people with a lysoso[...]

  148. Sept. 26, 2016

    Battling Brain Cancers Through Genomics

    A study of the classification of genetic alterations common to gliomas indicates that molecular methods can do a better job than current methods of predicting which specific treatment course is necessary for each indivi[...]

  149. Aug. 30, 2016

    NMO: Defining the spectrum, discovering new treatments

    Historically misdiagnosed as multiple sclerosis, neuromyelitis optica (NMO) is characterized by more-severe attacks and less complete recovery. Timely, accurate diagnosis is critical for appropriate treatment.

  150. Aug. 30, 2016

    Heart Brain Clinic: Team approach to stroke

    Patients with neurological symptoms that may be due to a cardiac etiology, such as atrial fibrillation or patent foramen ovale, benefit from a team approach to treatment management.

  151. June 28, 2016

    The next generation of epilepsy treatment

    Researchers employ a wide range of neurostimulation devices — including deep brain, cortical and hippocampal stimulation — in an effort to individualize treatment for patients who haven't responded to medica[...]

  152. June 28, 2016

    Acoustic neuroma: Treatment and quality of life

    Although benign, acoustic neuromas can impact patients' quality of life significantly. Common symptoms include unilateral hearing loss and tinnitus. Mayo Clinic specialists offer a range of individualized treatment opti[...]

  153. June 28, 2016

    Severe spinal deformity correction

    Specialists use intraoperative monitoring (IOM) of the spinal cord and intraoperative CT image guidance to facilitate placement of more-robust implants with novel trajectories that better stabilize complex spinal deform[...]

  154. June 28, 2016

    Intraoperative monitoring: Cooperation to improve outcomes

    In Mayo Clinic's team-based practice, intraoperative monitoring (IOM) to measure neural function and integrity is performed by highly trained technicians and monitored by a neurophysiologist on-site. Standard protocols [...]

  155. May 24, 2016

    The Heart Brain Clinic: Optimal team-based coordinated care

    The Heart Brain Clinic provides multidisciplinary evaluations to patients with neurological symptoms that may be attributable to a cardiac etiology such as patent foramen ovale or atrial fibrillation.

  156. April 29, 2016

    Minimally invasive spinal surgery

    Minimally invasive spinal surgery generally entails less pain and blood loss, a shorter hospital stay, and outcomes comparable to open surgery.

  157. April 29, 2016

    Glioma: New classification and the search for treatment

    Researchers have defined five biologically distinct tumor groups that may suggest pathways for developing more-precise treatments for patients with gliomas.

  158. April 29, 2016

    3-D printing for endovascular surgery

    Mayo surgeons practice complex vascular surgeries on replicated models of individual patients' aneurysms. The models are based on extensive imaging from angiograms and PET scans and built with 3-D printers.

  159. Feb. 25, 2016

    Surgery and ICU: Collaborating for the best outcomes

    Nearly 64 percent of patients treated for aneurysmal subarachnoid hemorrhage (aSAH) at Mayo Clinic's Minnesota campus from 2001 to 2013 had excellent functional outcome at last follow-up visit within one year of aSAH.

  160. Jan. 09, 2016

    Exploring the connection between traumatic brain injury and Alzheimer's disease: A population-based medical record review analysis

    A Mayo research team was awarded a Department of Defense grant to explore the connection between traumatic brain injury and Alzheimer's disease and related conditions using a population-based medical record review.

  161. Dec. 23, 2015

    Autoimmune dementia: Defining a treatable disorder

    Patients whose symptoms mimic those of neurodegenerative dementias may have a treatable autoimmune cause for their conditions. Mayo's standardized approach to evaluation of suspected autoimmune neurological disorders in[...]

  162. June 19, 2015

    Complexities of low CSF volume headache

    Spontaneous intracranial hypotension (SIH) is typically the result of spontaneous cerebral spinal fluid (CSF) leak at the spine level. It now appears that the core pathogenic factor in SIH is decreased CSF volume rather[...]

  163. March 14, 2015

    Intraspinal stimulation shows promise for restoring function after spinal cord injury

    Mayo Clinic researchers are studying the use of electronic devices that can wirelessly transmit signals from the brain to the intact spinal cord circuitry below the injury.

  164. Feb. 20, 2015

    Autoimmune GI dysmotility: A new direction

    Autoimmune GI dysmotility is a newly described clinical entity that is a limited manifestation of autoimmune dysautonomia, and can occur as an idiopathic phenomenon. Researchers report the first objective evidence that [...]

  165. Dec. 23, 2014

    Success with treating some superficial siderosis cases

    MRI of the head is key to diagnosing superficial siderosis - Superficial siderosis progresses slowly over decades. MRI sequences, such as gradient-echo sequencing, allow hemosiderin deposits caused by recurrent bleeding[...]

  166. Sept. 17, 2014

    New approach to autoimmune epilepsy

    Accumulating evidence indicates that autoimmune factors may play a bigger role in seizure disorders than previously suspected, often without full features of limbic encephalitis.

  167. July 16, 2014

    Characterizing progressive apraxia of speech

    Research studies involving patients with SLDs focus on primary progressive aphasia and primary progressive apraxia of speech in the context of neurodegenerative cognitive and motor disorders.