News

  1. Jun 25, 2019

    Halting the circle: Comprehensive neurogenetics test panels

    Mayo Clinic's use of comprehensive next-generation sequencing panels for the diagnosis of neurogenetic disorders covers the expanding genotype-phenotype complexity of these conditions, facilitating timely, accurate diag[...]

  2. Jun 25, 2019

    Headache disorders: Subspecialized, compassionate care

    Headache neurologist Jonathan H. Smith, M.D., answers questions about subspecialized management of headache disorders.

  3. Jun 25, 2019

    Cavernous malformations: 7-tesla MRI enhances expertise

    Mayo specialists use 7-tesla MRI advanced imaging technology to aid diagnosis and decisions about whether cavernous malformations should be surgically removed to prevent bleeding.

  4. Jun 25, 2019

    Onco-epilepsy: Simultaneous management of tumor and seizures

    Mayo's multidisciplinary, proactive approach facilitates the safe removal of noneloquent tissue that is potentially epileptogenic, to manage tumor and epilepsy at the same time.

  5. Jun 25, 2019

    Research highlights in Neurology and Neurosurgery ― May 2018

    Studies address cerebral microbleeds and amyloid burden, treatment outcomes for spinal cord low-grade gliomas, and unplanned returns to the operating room following neurosurgery.

  6. Apr 26, 2019

    Investigating autoinflammatory epileptic encephalopathies in children

    Mayo specialists answer questions about pediatric epileptic encephalopathies caused by neuroinflammation in the absence of antibodies, which can present with signs and symptoms similar to those of autoimmune epilepsy.

  7. Apr 26, 2019

    Coordinated management of young-onset Parkinson's disease

    A new clinic addresses the needs of people who are diagnosed with Parkinson's disease while still working, raising children and living a more active lifestyle than people diagnosed in their late 60s.

  8. Apr 26, 2019

    Melding technology and expertise for optimal spinal surgery

    Spinal surgery at Mayo Clinic combines advanced technology with the personalized expertise of a multidisciplinary treatment team to deliver optimal outcomes for patients with spinal conditions.

  9. Mar 1, 2019

    Vascular pathologies and Alzheimer's disease: Probing genetic pathways

    With funding from the National Institutes of Health M2OVE-AD Consortium, Mayo researchers investigate genetic pathways that may contribute to both vascular pathologies and Alzheimer's disease.

  10. Mar 1, 2019

    Endoscopic skull base surgery: The advantages of Mayo's team approach

    Mayo Clinic specialists have extensive experience with endoscopic skull base surgery for the treatment of pituitary tumors, meningiomas, clival tumors, chordomas and craniopharyngiomas.

  11. Mar 1, 2019

    Research highlights in Neurology and Neurosurgery – March 2019

    Studies address atypical presentations of central nervous system tumors, APOE e4 and Lewy bodies pathology, and obstructive sleep apnea related to unexpected death in people with epilepsy.

  12. Mar 1, 2019

    Neurofibromatosis Clinic: A team for lifelong care

    At Mayo Clinic, multidisciplinary teams of specialists collaborate to manage neurofibromatosis types 1 and 2 (NF1 and NF2) in children and adults.

  13. Jan 11, 2019

    Pediatric care in Arizona and Florida

    Mayo Clinic collaborates with Phoenix Children's Hospital in Arizona and Wolfson Children's Hospital in Florida to provide certain pediatric neurological and neurosurgical services. The collaborations offer pediatric pa[...]

  14. Jan 11, 2019

    Team approach for optimal tumor care

    Mayo's pediatric brain tumor laboratory has screened thousands of promising drugs in numerous cancer cell lines, uncovering pathways such as signal transducer and activator of transcription 3 (STAT3) proteins and Aurora[...]

  15. Jan 11, 2019

    Neonatal brachial plexus injuries: An integrated approach

    Mayo Clinic's multidisciplinary team approach to neonatal brachial plexus surgery allows for surgical reconstruction tailored to the individual patient's needs — nerve surgery, tendon transfers and shoulder-to-han[...]

  16. Jan 11, 2019

    Advances in pediatric refractory epilepsy

    Quantitative morphometric MRI analysis provides voxel-by-voxel comparisons between patient MRIs and a normative pediatric sample to detect the subtle signs of focal cortical dysplasia in children and guide decisions abo[...]

  17. Dec 11, 2018

    Neurosurgery registry for continuous improvement of care and quality of life

    Mayo's neurosurgery registry improves patient safety and outcomes by detailing surgical and patient-reported outcomes for all neurosurgical procedures performed at Mayo Clinic. The registry augments efforts to collect s[...]

  18. Dec 11, 2018

    Spinal oncology: Multidisciplinary approach for complex care

    Mayo Clinic provides multidisciplinary, subspecialized expertise to manage care for people with even the most complex intradural and vertebral tumors, including both primary and metastatic disease.

  19. Dec 11, 2018

    CREST-2 update: Enrolling patients for optimal care

    Mayo neurologist Kevin M. Barrett, M.D., answers questions about the Carotid Revascularization Endarterectomy Versus Stenting Trial 2 (CREST-2), a multicenter, randomized study that compares methods to identify an optim[...]

  20. Dec 11, 2018

    7-Tesla MRI: Pioneering use for patient care

    Clinical use of 7-Tesla MRI enhances Mayo Clinic's ability to manage epilepsy, certain brain and peripheral nerve tumors, and other neurological disorders.

  21. Mayo-researchers-correlate-specific-antibody-with-relapse-of-neurological-disorder

    Nov 6, 2018

    Mayo researchers correlate specific antibody with relapse of neurological disorder

    ROCHESTER, Minn. ? For patients who have been diagnosed with acute disseminated encephalomyelitis (ADEM), Mayo researchers have found a direct correlation between a specific antibody, myelin oligodendrocyte glycoprotein ? [...]

  22. Nov 3, 2018

    Beyond the status quo: Technical advances in neurosurgery

    Innovations in technology applications, imaging techniques and minimally invasive surgical approaches, plus a thorough assessment of the impact on patient care, maximize both safety and outcomes for patients at Mayo Cli[...]

  23. Nov 3, 2018

    Cavernous angiomas: Infrastructure for future drug trials

    Mayo Clinic participates in the multicenter Study of Trial Readiness in Cavernous Angiomas with Symptomatic Hemorrhage, intended to construct workable models for future therapeutic trials for treatment of the rare cereb[...]

  24. New-mobile-assessment-saves-brain-cells-during-stroke

    Oct 29, 2018

    New mobile assessment saves brain cells during stroke

    JACKSONVILLE, Fla.?? Every year, more than?795,000 people?in the U.S. have a stroke, which remains the leading cause of serious long-term disability and costs the nation?$34 billion?annually, according to the Centers for D[...]

  25. Helping-Others-Heal-3-D-models-improve-patient-care-and-surgical-outcomes

    Oct 24, 2018

    Helping Others Heal: 3-D models improve patient care and surgical outcomes

    The soft glow of Amy Alexander's alarm clock in the darkness toyed with her attempt to fall back to sleep. Her thoughts wandered to the job she left on the printer the night before. Knowing she wouldn't rest until she knew[...]

  26. Sep 12, 2018

    Minimally invasive surgery for craniosynostosis

    Minimally invasive surgery can be performed earlier than open surgery for infants with craniosynostosis — with the same outcomes. Babies with multiple suture or syndromic conditions may also benefit.

  27. Cautious-optimism-for-early-results-of-new-Alzheimers-drug

    Jul 24, 2018

    Cautious optimism for early results of new Alzheimer's drug

    With roughly 1 in 10 Americans over 65 living with Alzheimer's disease, any progress in the effort to fight the disease would be a welcome advancement for millions of people. Experts at Mayo Clinic are cautiously optimisti[...]

  28. May 22, 2018

    Novel MOG assay aids diagnosis of demyelinating diseases

    Mayo Clinic has developed the first test available in the United States to identify the myelin oligodendrocyte glycoprotein (MOG) antibody in patients' blood. The MOG antibody can distinguish a spectrum of autoimmune de[...]

  29. May 22, 2018

    Subspecialized neuro-ophthalmology care

    Mayo neuro-ophthalmologists work closely with neurologists and neurosurgeons to treat people with any problems involving sight or eye movement that arise from the nervous system, including migraine, stroke or multiple s[...]

  30. May 19, 2018

    AVM: Multimodal approach for individualized treatment

    Mayo specialists' multimodal approach to the treatment of arteriovenous malformations (AVMs) encompasses microsurgical resection, endovascular embolization, stereotactic radiosurgery and awake surgery, as well as watchf[...]

  31. May 19, 2018

    Minimally invasive brain surgery: Safer treatment of deep-seated lesions

    Minimally invasive surgery using a tubular retractor system can be an option for selected patients with subcortical high-grade glioma, metastatic brain tumors or vascular lesions.

  32. May 2, 2018

    Mayo Clinic Minute: How artificial intelligence could improve outcomes for stroke patients

    People use artificial intelligence ? or AI ? any time they ask Siri, Alexa or Google to help them find something. But AI is also changing how health care providers treat patients. "Finding data that's faster, that works co[...]

  33. Apr 27, 2018

    Advances in endoscopic skull base surgery

    Mayo specialists employ image guidance and intraoperative CT, 3-D endoscopy, simulations that integrate endoscopic surgery and proton beam therapy, and 3-D models and holography for pre-surgical planning to treat pituit[...]

  34. Apr 27, 2018

    Groundbreaking trial of stem cell treatment for intracerebral hemorrhage

    Mayo Clinic is conducting a clinical trial of stem cell treatment for intracerebral hemorrhage (ICH). Investigators hope that results will lead to therapies that provide neuronal protection or recovery for people with I[...]

  35. Apr 27, 2018

    Clinical trial of stem cell therapy for traumatic spinal cord injury

    Mayo Clinic is enrolling patients in a clinical trial of adipose stem cell treatment for spinal cord injury caused by trauma. Participants will receive intrathecal injections of adipose-derived mesenchymal stem cells. N[...]

  36. Apr 3, 2018

    Mayo Clinic to coordinate new effort to expand medical research, expert care for Lewy body dementia patients

    ROCHESTER, Minn. ? Lewy body dementia is the second most common type of progressive dementia after Alzheimer?s disease, but it is underdiagnosed, says Bradley Boeve, M.D., a Mayo Clinic neurologist. A new program among res[...]

  37. Mar 28, 2018

    Mayo study shows easy-to-use, noninvasive stimulation device can help prevent migraine attacks

    SCOTTSDALE, Arizona ? A migraine is much more than just a bad headache. Migraine symptoms, which can be debilitating for many people, are the sixth leading cause of disability, according to the World Health Organization. W[...]

  38. Feb 15, 2018

    Minimally invasive options for medically refractory epilepsy

    The Stereotactic Laser Ablation for Temporal Lobe Epilepsy (SLATE) clinical trial tests the efficacy of MRI-guided laser ablation for mesial temporal sclerosis. The approach allows patients to avoid open temporal lobect[...]

  39. Feb 12, 2018

    When the body attacks the brain: Immune system often to blame for encephalitis, study finds

    ROCHESTER, Minn. ? Encephalitis caused by the immune system attacking the brain is similar in frequency to encephalitis from infections, Mayo Clinic researchers report in Annals of Neurology. Encephalitis is a term used to[...]

  40. Jan 30, 2018

    Timely ALS care in Florida

    At Mayo Clinic's campus in Jacksonville, Florida, patients with amyotrophic lateral sclerosis (ALS) benefit from a holistic approach to care, including coordinated appointments that ensure prompt intervention, remote fo[...]

  41. Jan 20, 2018

    Regenerative medicine: Potential to improve life after brain tumor treatment

    Studies suggest that radiation used to treat brain tumors accelerates aging-like changes in the brain. Mayo researchers are working to minimize the amount of brain exposed to radiation and develop strategies to help rej[...]

  42. Jan 9, 2018

    Most patients with unknown spinal cord disease later given specific diagnosis, study shows

    ROCHESTER, Minn. ? A study by Mayo Clinic researchers found that most patients with suspected spinal cord inflammation of unknown cause have an alternative, specific diagnosis. The research is published in Neurology, the m[...]

  43. Dec 29, 2017

    Individualized approach for complex intracranial aneurysms

    Mayo neurovascular specialists manage complex intracranial aneurysms successfully — with low morbidity and low mortality — through the use of treatment modalities such as extracranial to intracranial bypass,[...]

  44. Dec 29, 2017

    Objective criteria for migraine

    Mayo researchers are using brain MRI to develop objective biomarkers for the classification of migraine. Their goal is to identify objective differences among people with migraine and other headache types that predict t[...]

  45. Dec 5, 2017

    Mayo Clinic researchers show how neuroblastoma spreads

    Mayo Clinic researchers show how neuroblastoma spreads: Mayo Clinic Forefront.

  46. Oct 24, 2017

    Intraneural perineuriomas: Common cause identified

    Researchers have identified a common cause for rare intraneural perineuriomas and an unexpected shared pathogenesis with intracranial meningiomas. The finding indicates a pathway for potential treatment.

  47. Oct 24, 2017

    Awake craniotomy for tumor resection in motor and sensory tissue

    Mayo neurosurgeons have successfully expanded their use of awake craniotomy from the removal of tumors in the cortical speech area of the brain to areas of eloquent motor and sensory tissue.

  48. Oct 13, 2017

    Deep brain stimulation for movement disorders

    Recent findings suggest that subthalamic nucleus deep brain stimulation (DBS) provokes dopamine release and that its concentration varies depending on the site being stimulated. DBS of the subthalamic nucleus has been s[...]

  49. Aug 30, 2017

    Tissue biopsy for identifying early Parkinson's

    Research indicates that submandibular gland needle biopsies can identify Lewy type alpha-synucleinopathy in people with Parkinson's disease of less than five years' duration.

  50. Aug 30, 2017

    Electromyography: Innovation and quality nationwide

    Mayo's board-certified electrophysiologists and technicians complete nerve conduction studies and needle examination of common and uncommon nerves and muscles — plus specialized tests such as diaphragmatic and per[...]

  51. Jul 27, 2017

    Signs and symptoms of Bell's palsy

    Bell's palsy causes sudden weakness in your facial muscles. This makes half of your face appear to droop. Your smile is one-sided, and your eye on that side resists closing. Bell's palsy, also known as facial palsy, can oc[...]

  52. Jul 25, 2017

    Mayo Clinic Q and A: Speech therapy after a stroke

    DEAR MAYO CLINIC: My mother had a stroke six months ago. Her mobility has returned to near normal. She can read and understands others when they speak. But she has a lot of difficulty talking, often struggling to find the [...]

  53. Jun 30, 2017

    Innovations in care, treatment improves prognosis for brain tumor patients

    Nearly 80,000 new cases of primary brain tumors are expected to be diagnosed this year in the U.S. A brain tumor is a mass or abnormal growth of cells that can develop from brain cells or cells within structures near the b[...]

  54. Jun 28, 2017

    Hope for patients with degenerative diseases such as Alzheimer?s begins in the lab

    Picture yourself on a train ride, looking out the window at the passing scenery ? a view?of the tracks in sight. The train steamrolls ahead at a steady pace for a while, then gradually picks up speed. But something?happens[...]

  55. Jun 27, 2017

    Posterior fossa parenchymal biopsy: Yield and safety

    A study of posterior fossa biopsies performed at Mayo Clinic from 1996 to 2009 indicates that, in carefully selected patients with inflammatory brain diseases, the posterior fossa is appropriate to cerebellar and brains[...]

  56. Jun 27, 2017

    Moyamoya disease: New approaches in Arizona

    Moyamoya disease can cause recurring transient ischemic attacks, strokes, seizures and cognitive deterioration, especially in young people. Mayo neurosurgeons are pioneering new approaches to treatment, to improve cereb[...]

  57. Jun 13, 2017

    Meet the investigator: Kristin R. Swanson, Ph.D.

    Kristin R. Swanson, Ph.D., of Mayo Clinic, discusses her brain cancer research: Mayo Clinic Forefront.

  58. Jun 7, 2017

    New international guidelines issued on dementia with Lewy bodies

    ROCHESTER, Minn. ? Susan Williams, wife of the late actor and comedian Robin Williams, called Lewy body disease ?the terrorist inside my husband?s brain.? An estimated 1.4 million Americans have dementia with Lewy bodies, [...]

  59. May 1, 2017

    Mayo Clinic researchers develop new tumor-shrinking nanoparticle to fight cancer, prevent recurrence

    JACKSONVILLE, Fla. ? A Mayo Clinic research team has developed a new type of cancer-fighting nanoparticle aimed at shrinking breast cancer tumors, while also preventing recurrence of the disease. In the study, published to[...]

  60. Apr 28, 2017

    Subthreshold cortical stimulation for epilepsy

    Mayo neurologists have successfully suppressed seizures in patients with drug-resistant focal epilepsy. In a 2016 study, 10 of 13 patients reported improvement for epilepsy severity and quality of life after chronic sub[...]

  61. Apr 3, 2017

    Man moves paralyzed legs using device that stimulates spinal cord

    ROCHESTER, Minn. ? Mayo Clinic researchers used electrical stimulation on the spinal cord and intense physical therapy to help a man intentionally move his paralyzed legs, stand and make steplike motions for the first time[...]

  62. Feb 22, 2017

    Strategy to prevent chemotherapy-induced neuropathy

    Mesenchymal stem cells act as therapy for nervous system diseases by carrying extracellular products across the blood-brain barrier in patients with amyotrophic lateral sclerosis. The stem cells may also be used to deli[...]

  63. Feb 22, 2017

    Targeted DNA sequencing for neurological conditions

    The neurology genomics clinic provides patients with complex neurological conditions with access to research, testing, diagnosis and treatment, plus recommended screening and counseling for family members.

  64. Feb 22, 2017

    Novel biomarker for a treatable meningoencephalomyelitis

    The antibody, which targets glial fibrillary acidic protein (GFAP), has only been found in patients with autoimmune meningoencephalomyelitis, a rapidly progressive neurological disorder. Mayo's clinical test for the GFA[...]

  65. Dec 29, 2016

    Clinical trials of cannabidiol for epilepsy

    Data from clinical trials of Epidiolex, a cannabidiol (CBD) treatment, for children with Dravet syndrome show that seizures were reduced by 39 percent in children treated with CBD versus only 16 percent in the placebo g[...]

  66. Dec 18, 2016

    Stereotactic radiosurgery is best for some brain tumors

    Mayo Clinic Forefront magazine: Shift in practice may reserve whole-brain radiation for patients with extensive disease.

  67. Nov 18, 2016

    Finding new treatments for high-grade pediatric brain tumors

    Brain and central nervous system tumors now represent the most common cause of cancer-related death in children. New information about the molecular diversity of these tumors points the way toward targeted therapies tai[...]

  68. Oct 28, 2016

    Proton beam therapy in Minnesota and Arizona

    Proton beam therapy targets tumors more precisely than photon radiation, limiting damage to surrounding healthy organs and tissue and offering the possibility of using higher doses of radiation for more-beneficial outco[...]

  69. Oct 28, 2016

    Elucidating lysosomal diseases

    Neurological findings with or without systemic changes in the skin, viscera, heart or bones may indicate lysosomal disease. Mayo researchers are conducting next-generation sequencing of the genes of people with a lysoso[...]

  70. Oct 28, 2016

    Lateral and percutaneous interbody fusions

    Minimally invasive procedures for interbody fusion, including lateral interbody fusion and percutaneous interbody fusion, can offer patients minimal blood loss, less pain, shorter hospitalization and quicker recovery.

  71. Aug 30, 2016

    Heart Brain Clinic: Team approach to stroke

    Patients with neurological symptoms that may be due to a cardiac etiology, such as atrial fibrillation or patent foramen ovale, benefit from a team approach to treatment management.

  72. Aug 30, 2016

    NMO: Defining the spectrum, discovering new treatments

    Historically misdiagnosed as multiple sclerosis, neuromyelitis optica (NMO) is characterized by more-severe attacks and less complete recovery. Timely, accurate diagnosis is critical for appropriate treatment.

  73. Jun 28, 2016

    Severe spinal deformity correction

    Specialists use intraoperative monitoring (IOM) of the spinal cord and intraoperative CT image guidance to facilitate placement of more-robust implants with novel trajectories that better stabilize complex spinal deform[...]

  74. Jun 28, 2016

    The next generation of epilepsy treatment

    Researchers employ a wide range of neurostimulation devices — including deep brain, cortical and hippocampal stimulation — in an effort to individualize treatment for patients who haven't responded to medica[...]

  75. Jun 28, 2016

    Intraoperative monitoring: Cooperation to improve outcomes

    In Mayo Clinic's team-based practice, intraoperative monitoring (IOM) to measure neural function and integrity is performed by highly trained technicians and monitored by a neurophysiologist on-site. Standard protocols [...]

  76. Jun 28, 2016

    Acoustic neuroma: Treatment and quality of life

    Although benign, acoustic neuromas can impact patients' quality of life significantly. Common symptoms include unilateral hearing loss and tinnitus. Mayo Clinic specialists offer a range of individualized treatment opti[...]

  77. May 24, 2016

    The Heart Brain Clinic: Optimal team-based coordinated care

    The Heart Brain Clinic provides multidisciplinary evaluations to patients with neurological symptoms that may be attributable to a cardiac etiology such as patent foramen ovale or atrial fibrillation.

  78. Apr 29, 2016

    Glioma: New classification and the search for treatment

    Researchers have defined five biologically distinct tumor groups that may suggest pathways for developing more-precise treatments for patients with gliomas.

  79. Apr 29, 2016

    Minimally invasive spinal surgery

    Minimally invasive spinal surgery generally entails less pain and blood loss, a shorter hospital stay, and outcomes comparable to open surgery.

  80. Apr 29, 2016

    3-D printing for endovascular surgery

    Mayo surgeons practice complex vascular surgeries on replicated models of individual patients' aneurysms. The models are based on extensive imaging from angiograms and PET scans and built with 3-D printers.

  81. Feb 25, 2016

    Surgery and ICU: Collaborating for the best outcomes

    Nearly 64 percent of patients treated for aneurysmal subarachnoid hemorrhage (aSAH) at Mayo Clinic's Minnesota campus from 2001 to 2013 had excellent functional outcome at last follow-up visit within one year of aSAH.

  82. Jan 9, 2016

    Exploring the connection between traumatic brain injury and Alzheimer's disease: A population-based medical record review analysis

    A Mayo research team was awarded a Department of Defense grant to explore the connection between traumatic brain injury and Alzheimer's disease and related conditions using a population-based medical record review.

  83. Dec 23, 2015

    Autoimmune dementia: Defining a treatable disorder

    Patients whose symptoms mimic those of neurodegenerative dementias may have a treatable autoimmune cause for their conditions. Mayo's standardized approach to evaluation of suspected autoimmune neurological disorders in[...]

  84. Jun 19, 2015

    Complexities of low CSF volume headache

    Spontaneous intracranial hypotension (SIH) is typically the result of spontaneous cerebral spinal fluid (CSF) leak at the spine level. It now appears that the core pathogenic factor in SIH is decreased CSF volume rather[...]

  85. Mar 14, 2015

    Intraspinal stimulation shows promise for restoring function after spinal cord injury

    Mayo Clinic researchers are studying the use of electronic devices that can wirelessly transmit signals from the brain to the intact spinal cord circuitry below the injury.

  86. Feb 20, 2015

    Autoimmune GI dysmotility: A new direction

    Autoimmune GI dysmotility is a newly described clinical entity that is a limited manifestation of autoimmune dysautonomia, and can occur as an idiopathic phenomenon. Researchers report the first objective evidence that [...]

  87. Dec 23, 2014

    Success with treating some superficial siderosis cases

    MRI of the head is key to diagnosing superficial siderosis - Superficial siderosis progresses slowly over decades. MRI sequences, such as gradient-echo sequencing, allow hemosiderin deposits caused by recurrent bleeding[...]

  88. Sep 17, 2014

    New approach to autoimmune epilepsy

    Accumulating evidence indicates that autoimmune factors may play a bigger role in seizure disorders than previously suspected, often without full features of limbic encephalitis.

  89. Jul 16, 2014

    Characterizing progressive apraxia of speech

    Research studies involving patients with SLDs focus on primary progressive aphasia and primary progressive apraxia of speech in the context of neurodegenerative cognitive and motor disorders.

  90. The Fish Farm

  91. New Alzheimer's gene pathway discovered

  92. Steering Cells through the Brain

  93. Dementia Mysteries Untangled

  94. Halting the Wheel of Misfortune: ‘A New Era’ in Migraine Care

  95. New directions in the study of Alzheimer’s disease

  96. Neuro-Oncology Testing [A Test in Focus]

  97. Battling Brain Cancers Through Genomics