Chemotherapy nausea and vomiting: Prevention is best defense

Not everyone experiences nausea and vomiting during chemotherapy. Find out if you're at risk of these side effects and what you and your doctor can do to prevent them.

By Mayo Clinic Staff

Nausea and vomiting are common side effects of chemotherapy treatment for cancer. But in most cases, these side effects can be controlled with preventive medications and other measures.

Who's at risk of chemotherapy nausea and vomiting?

Whether you'll experience nausea and vomiting as a result of chemotherapy depends on:

  • What chemotherapy drugs you receive and their dosage
  • Whether you receive other cancer treatments — such as radiation — during your chemotherapy treatment
  • Whether you've experienced nausea and vomiting in the past

Chemotherapy drugs are classified into four different categories based on the likelihood they will cause nausea and vomiting: high, moderate, low or minimal. If you get one of the drugs that is known to cause nausea and vomiting, your doctor will probably give you preventive medicine.

Whether a drug will cause nausea and vomiting also depends on the amount you receive. Some drugs may be less likely to cause side effects at lower doses. Ask your doctor whether your treatment plan is likely to cause nausea and vomiting.

Personal factors that may increase your risk

Not everyone reacts to chemotherapy in the same way. Certain factors may make you more vulnerable to treatment-related nausea and vomiting.

You may be more vulnerable if one or more of the following apply to you:

  • You're a woman.
  • You're younger than 50.
  • You've experienced nausea and vomiting with previous treatments, or you have a history of motion sickness.
  • You have a high level of anxiety.
  • You experienced morning sickness during pregnancy.
  • You are prone to vomiting when you're sick.
  • You have a history of drinking little or no alcohol.

Also, if you expect that your treatment will cause nausea and vomiting, there's a chance that it will. This might happen if you think that all cancer treatments cause these side effects, which isn't true. Your doctor can tell you whether the treatment you'll receive is likely to cause nausea and vomiting.

How do doctors prevent nausea and vomiting?

Most people undergoing chemotherapy receive anti-nausea (anti-emetic) medications to prevent nausea and vomiting.

There are many medications used to prevent nausea and vomiting. Your doctor chooses anti-nausea medications based on how likely your chemotherapy drugs are to cause nausea and vomiting. You may take as few as one to as many as four medications, depending on your situation.

Your doctor will give you some medications before the chemotherapy and then will instruct you on which medications to take on a regular schedule on the days after the chemotherapy and which medications to take only if you feel nauseated.

Doctors take this proactive approach to prevent nausea and vomiting because these side effects can be difficult to control once they begin. Nausea and vomiting can make you feel miserable, add to your fatigue and distress, and make you reluctant to stick to your treatment schedule.

What additional measures can you take to prevent nausea and vomiting?

You can take steps to reduce your risk of nausea and vomiting. For example:

  • Eat small meals. Stagger small meals throughout the day rather than eating fewer, larger meals. If possible, don't skip meals. Eating a light meal a few hours before treatment also may help.
  • Eat what appeals to you. It's best, however, to avoid foods that are sweet, fried or fatty. In addition, cool foods may give off less bothersome odors.

    Cook and freeze meals in advance of treatment to avoid cooking when you're not feeling well. Or have someone else cook for you.

  • Drink lots of fluids. Try cool beverages, such as water, unsweetened fruit juices, tea or ginger ale that's lost its carbonation. It may help to drink small amounts throughout the day, rather than larger amounts less frequently.
  • Avoid unpleasant smells. Pay attention to what smells trigger nausea for you and limit your exposure to unpleasant smells. Fresh air may help.
  • Make yourself comfortable. Rest after eating, but don't lie flat for a couple of hours. Try wearing loosefitting clothing and distracting yourself with other activities.
  • Use relaxation techniques. Examples include meditation and deep breathing.
  • Consider complementary therapies. Complementary and alternative therapies, such as acupuncture and aromatherapy, may help you feel better when used in combination with medications from your doctor. Tell your doctor if you're interested in trying these treatments. He or she may be able to recommend a practitioner who works with people undergoing cancer treatments.

These self-care measures may help you prevent nausea and vomiting, but they can't take the place of anti-nausea medications.

If you begin to feel nauseated despite the medications, call your doctor. Treatments may include additional medications, though your individual treatment will depend on what's causing your signs and symptoms.

April 16, 2022 See more In-depth

See also

  1. Acute lymphocytic leukemia
  2. Acute myelogenous leukemia
  3. Adjuvant therapy for cancer
  4. Anal cancer
  5. Atypical cells: Are they cancer?
  6. Beating Ovarian Cancer
  7. Biliary tract cancer: Should I get a second opinion?
  8. Biopsy procedures
  9. Bladder cancer
  10. Infographic: Bladder Cancer
  11. What is bladder cancer? A Mayo Clinic expert explains
  12. Bladder cancer FAQs
  13. Bladder cancer treatment options
  14. Infographic: Blood Cancer Awareness
  15. Blood Cancers and Disorders
  16. Bone cancer
  17. Bone metastasis
  18. Brain tumor
  19. What is a brain tumor? A Mayo Clinic expert explains
  20. Brain tumor FAQs
  21. Breast cancer
  22. Breast Cancer
  23. Breast cancer chemoprevention
  24. Breast Cancer Education Tool
  25. Common questions about breast cancer treatment
  26. Infographic: Breast Cancer Risk
  27. Breast cancer staging
  28. Breast cancer types
  29. Infographic: Breast Reconstruction Options
  30. Dr. Wallace Video
  31. Dr. Mark Truty (surgery, MN) better outcomes with chemo
  32. CA 125 test: A screening test for ovarian cancer?
  33. Cancer
  34. Cancer
  35. Cancer blood tests
  36. Myths about cancer causes
  37. Infographic: Cancer Clinical Trials Offer Many Benefits
  38. Cancer diagnosis: 11 tips for coping
  39. Cancer-related fatigue
  40. Cancer pain: Relief is possible
  41. Cancer risk: What the numbers mean
  42. Cancer surgery
  43. Cancer survival rate
  44. Cancer survivors: Care for your body after treatment
  45. Cancer survivors: Late effects of cancer treatment
  46. Cancer survivors: Managing your emotions after cancer treatment
  47. Cancer treatment decisions: 5 steps to help you decide
  48. Cancer treatment myths
  49. Carcinoid syndrome
  50. Castleman disease
  51. Cervical cancer
  52. What is cervical cancer? A Mayo Clinic expert explains
  53. Cervical cancer FAQs
  54. Cervical dysplasia: Is it cancer?
  55. Chemo Targets
  56. Chemotherapy
  57. Chemotherapy and hair loss: What to expect during treatment
  58. Chemotherapy and sex: Is sexual activity OK during treatment?
  59. Chemotherapy side effects: A cause of heart disease?
  60. Cholangiocarcinoma (bile duct cancer)
  61. Choroid plexus carcinoma
  62. Chronic lymphocytic leukemia
  63. Chronic myelogenous leukemia
  64. Collecting Pennies Through the Pain
  65. Colon cancer
  66. Colon Cancer Family Registry
  67. Colon cancer screening: At what age can you stop?
  68. Colon cancer screening
  69. Colorectal Cancer
  70. Curcumin: Can it slow cancer growth?
  71. Cutaneous T-cell lymphoma
  72. Cancer-related diarrhea
  73. Dragon Boats and Breast Cancer
  74. Eating during cancer treatment: Tips to make food tastier
  75. Embryonal tumors
  76. Endometrial cancer
  77. Ependymoma
  78. Esophageal cancer
  79. Infographic: Esophageal Cancer
  80. Esophageal Cancer
  81. Ewing sarcoma
  82. Fertility preservation
  83. Frequent sex: Does it protect against prostate cancer?
  84. Gallbladder cancer
  85. Genetic Testing for Breast Cancer
  86. Genetic testing for breast cancer: Psychological and social impact
  87. GI Stents
  88. Glowing Cancer Surgery
  89. Gynecologic Cancers
  90. Hairy cell leukemia
  91. Have brown or Black skin? Use sunscreen
  92. Head and Neck Cancer
  93. Head and Neck Cancer Transoral Surgery
  94. Head and neck cancers
  95. Heart cancer: Is there such a thing?
  96. High-dose vitamin C: Can it kill cancer cells?
  97. Hodgkin's lymphoma (Hodgkin's disease)
  98. Hodgkin's vs. non-Hodgkin's lymphoma: What's the difference?
  99. Infographic: HPV Related Oral Cancers
  100. Inflammatory breast cancer
  101. Infographic: Innovative Rectal Cancer Treatments
  102. Invasive lobular carcinoma
  103. Is a clinical trial for biliary tract cancer right for me?
  104. Leukemia
  105. Liver cancer
  106. Infographic: Liver Cancer
  107. What is liver cancer? An expert explains
  108. Liver cancer FAQs
  109. Infographic: Liver Transplant Bile Duct Cancer
  110. Living with biliary tract cancer
  111. Living with Brain Tumors
  112. Long Term Brain Cancer Survivor
  113. Low blood counts
  114. Lung cancer
  115. Infographic: Lung Cancer
  116. Lung Cancer
  117. Lung nodules: Can they be cancerous?
  118. Magic mouthwash
  119. Male breast cancer
  120. What is breast cancer? An expert explains
  121. Measles Virus as a Cancer Fighter
  122. Melanoma
  123. Merkel cell carcinoma
  124. Mesothelioma
  125. Monoclonal antibody drugs
  126. Mort Crim and Cancer
  127. Mouth cancer
  128. What is mouth cancer? A Mayo Clinic expert explains
  129. Mouth cancer FAQs
  130. Mouth sores caused by cancer treatment: How to cope
  131. Multiple myeloma
  132. Infographic: Multiple Myeloma
  133. Myelofibrosis
  134. Myelofibrosis
  135. Nasopharyngeal carcinoma
  136. Neuroblastoma
  137. Neuroendocrine tumors
  138. Neuroendocrine Tumors NETs
  139. Neurofibromatosis
  140. New immunotherapy approved for metastatic bladder cancer
  141. No appetite? How to get nutrition during cancer treatment
  142. Non-Hodgkin's lymphoma
  143. Oligodendroglioma
  144. Osteosarcoma
  145. Living with an ostomy
  146. Ovarian cancer
  147. Ovarian cancer: Still possible after hysterectomy?
  148. Paget's disease of the breast
  149. Palliative care for biliary tract cancer
  150. Pancreatic cancer
  151. Pancreatic Cancer
  152. What is pancreatic cancer? A Mayo Clinic expert explains
  153. Infographic: Pancreatic Cancer: Minimally Invasive Surgery
  154. Pancreatic Cancer Survivor
  155. Infographic: Pancreatic Cancers-Whipple
  156. Pap test: Can it detect ovarian cancer?
  157. Paulas story A team approach to battling breast cancer
  158. Peripheral nerve tumors
  159. Pheochromocytoma
  160. Pineoblastoma
  161. Pink Sisters
  162. Pomegranate juice: A cure for prostate cancer?
  163. Precision medicine: A new way to treat biliary cancers
  164. Prostate Cancer
  165. Prostate cancer
  166. Prostate cancer: Does PSA level affect prognosis?
  167. What is prostate cancer? A Mayo Clinic expert explains
  168. Infographic: Prostate Cancer: Choline c-11
  169. Prostate cancer metastasis: Where does prostate cancer spread?
  170. Prostate cancer prevention
  171. Prostate cancer FAQs
  172. Infographic: Proton Beam Brain Tumor
  173. Proton Beam Therapy
  174. Punk Guitarist Survives Brain Tumor
  175. Rectal cancer
  176. Recurrent breast cancer
  177. Retinoblastoma
  178. Robotic bladder surgery
  179. Salivary gland tumors
  180. Infographic: Scalp Cooling Therapy for Cancer
  181. Scientists propose a breast cancer drug for some bladder cancer patients
  182. Scrotal masses
  183. Self-Image During Cancer
  184. Skin cancer
  185. Infographic: Skin Cancer
  186. Skin Cancer Reconstruction
  187. Melanoma pictures to help identify skin cancer
  188. Radiation simulation
  189. Small cell, large cell cancer: What this means
  190. Soft tissue sarcoma
  191. Spinal cord tumor
  192. Spray tanning? Hold your breath
  193. Stomach cancer
  194. Infographic: Stomach Cancer
  195. What is stomach cancer? A Mayo Clinic expert explains
  196. Stomach cancer FAQs
  197. Summer sun: Know the danger zone
  198. Super Survivor Conquers Cancer
  199. Testicular cancer
  200. Testicular microlithiasis
  201. Thalidomide: Research advances in cancer and other conditions
  202. The Long Race Beating Cancer
  203. Throat cancer
  204. Thyroid cancer
  205. Thyroid Cancer
  206. What is thyroid cancer? A Mayo Clinic expert explains
  207. Thyroid cancer FAQs
  208. Treatment options for biliary tract cancer
  209. Tumor vs. cyst: What's the difference?
  210. Vaginal cancer
  211. Vertebral tumor
  212. Melanoma — Early stage and advanced melanoma
  213. How cancer spreads
  214. PICC line placement
  215. Skin cancer — How skin cancer develops
  216. Vulvar cancer
  217. Weight Loss After Breast Cancer
  218. What is biliary tract cancer?
  219. When cancer returns: How to cope with cancer recurrence
  220. Wilms tumor
  221. Zollinger-Ellison syndrome