The most common causes of muscle pain are tension, stress, overuse and minor injuries. This type of pain is usually localized, affecting just a few muscles or a small part of your body.

Systemic muscle pain — pain throughout your whole body — is more often the result of an infection, an illness or a side effect of a medication.

Common causes of muscle pain include:

1. Chronic exertional compartment syndrome
2. Chronic fatigue syndrome
3. Claudication
4. Coronavirus disease 2019 (COVID-19)
5. Dermatomyositis
6. Dystonia
7. Fibromyalgia
8. Hypothyroidism (underactive thyroid)
9. Influenza (flu) and other viral illness (influenza-like illness)
10. Lupus
11. Lyme disease
12. Medications, especially the cholesterol medications known as statins
13. Muscle cramp
14. Myofascial pain syndrome
15. Polymyalgia rheumatica
16. Polymyositis (inflammatory disease that causes muscle weakness)
17. Repetitive strain injuries
18. Rheumatoid arthritis (inflammatory joint disease)
19. Rocky Mountain spotted fever
20. Sprains

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March 27, 2021