75 岁以上者，如果从 50 岁开始定期接受结肠癌筛查，筛查结果一直为阴性，没有息肉（腺瘤）或结肠癌，并且不会因家族史而增加结肠癌风险，则可能无需继续进行常规筛查。美国预防服务工作组（USPSTF）和美国医师协会（ACP）发布的结肠癌筛查指南如是建议。
年龄上限的设定依据是研究确定 75 岁后筛查的净获益很小。不过，USPSTF 依然建议对 75 岁以上且有更高风险患结肠癌的人群进行结肠癌监测，这些风险因素包括家族史、既往确诊的结肠癌或腺瘤性息肉。
美国癌症协会和美国胃肠学院未就不再建议结肠癌筛查设定具体的年龄上限。
USPSTF 和 ACP 建议使用一种或多种筛查策略进行结肠癌筛查：
- 结肠镜检查
- 大便潜血试验（FOBT）
- 粪便免疫化学试验（FIT）
- 粪便 DNA 检测
- 乙状结肠镜检查
- 计算机断层扫描结肠成像检查（仿真结肠镜检查）
向医生咨询哪种结肠癌筛查方法最适合您。您可以一起根据您的整体健康状况来决定何时筛查可能不再获益。
Jan. 11, 2022
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