News April 02, 2025 Advancing patient care through glaucoma research Glaucoma is the leading cause of irreversible blindness with 80 million patients affected worldwide. Mayo Clinic researchers are focused on developing improved treatment for reducing intraocular pressure, while also ide[...] April 02, 2025 Research and new technology aid in improving IOL prediction accuracy, patient outcomes There is a constant call for improvement in IOL power calculation accuracy. To achieve this in an increased number of patients – while also improving accuracy in patients with less common eye measurements – researchers [...] April 02, 2025 Residents highlight camaraderie, robust educational foundation Mayo Clinic's Ophthalmology Residency draws trainees from diverse backgrounds, family status, and professional and personal interests. Learn more about some Mayo Clinic residents' experiences so far. Jan. 17, 2025 Catch up on our top 10 podcasts of 2024 Discover the top 10 most-popular 2024 Mayo Clinic Ophthalmology Podcasts, hosted by Erick D. Bothun, M.D., and Andrea A. Tooley, M.D. Nov. 23, 2024 Valuable addition to the team brings shared dedication to patients, passion for research and education Greg J. Griepentrog, M.D., has joined Ophthalmology at Mayo Clinic in Rochester, Minnesota, bringing his own unique experience and knowledge. Nov. 23, 2024 First FDA-approved retinal gene therapy available at Mayo Clinic The first prescription retinal gene therapy product is now available at Mayo Clinic. For eligible patients, voretigene neparvovec-rzyl is a one-time gene therapy that has the potential to restore the visual cycle and to[...] Nov. 23, 2024 Pediatric myopia clinic prioritizes early intervention and research Early intervention and detection in children with myopia is the key to reducing the long-term impact on patients' ocular health. Mayo Clinic's pediatric myopia clinic offers coordinated care within a multidisciplinary t[...] Oct. 30, 2024 Global track for residents: International education, bidirectional impact Mayo Clinic introduced a new global ophthalmology and health equities track that thoughtfully prepares residents for local and international experiences. Oct. 25, 2024 Macular hole repair does not require face-down positioning Older patients benefit from macular hole surgery without face-down positioning - Surgery with broad ILM peeling, 20 percent sulfur hexafluoride gas and no face-down positioning may be effective in the treatment of idiop[...] Oct. 25, 2024 SCOPE research tracks increased use, performance of scleral lenses The Scleral Lenses in Current Ophthalmic Practice: An Evaluation (SCOPE) study group works to provide a better understanding of the role and performance of scleral lenses in clinical practice. Oct. 25, 2024 Intense pulsed light for treatment of dry eye disease A retrospective study confirms that intense pulsed light (IPL) and meibomian gland expression (MGX) treatment can improve dry eye symptoms and offers a reasonable option for patients who have not shown improvement with [...] Aug. 28, 2024 Transforming healthcare and research with AI-driven tools Through its patient care and research initiatives, Mayo Clinic has been busy building one of the largest repositories of clinical data in the world. One of the AI-driven tools developed within Mayo Clinic Ophthalmology [...] Aug. 14, 2024 3D-printed models aid complex orbital reconstruction When conditions such as cancer, trauma or complications from previous surgery affect the eyes, as well as surrounding facial structures, patients can benefit from a multidisciplinary approach. The Mayo Clinic Oculofacia[...] Aug. 14, 2024 Ophthalmic Pathology at Mayo Clinic Mayo Clinic has had a longtime tradition of expertise and excellence in the field of ophthalmic pathology. Currently, Ophthalmic Pathology includes four subspecialized pathologists who review more than 800 cases every y[...] March 16, 2024 Expanding pediatric cornea, cataract and glaucoma care Dr. Kim will help care for children with complex anterior segment disorders, specifically in the areas of pediatric cornea, cataract and glaucoma. March 16, 2024 Individualizing patient care through research, expertise Ruti Sella Svetlit, M.D., brings her expertise in anterior segment ocular surgery and refractive surgery to help treat patients with cataract and refractive error at Mayo Clinic in Rochester, Minnesota. Jan. 16, 2024 Collaborative surgical innovation can reduce complications and hospital stay Meningiomas account for 15% to 20% of primary brain tumors. Mayo Clinic ophthalmologists collaborating across the clinical practice has allowed a new treatment option to emerge for anterior skull base meningioma resecti[...] Oct. 14, 2023 Dry eye clinic offers new testing and treatments Mayo Clinic's new dry eye clinic offers new imaging and treatment options, along with comprehensive, multidisciplinary care. Oct. 14, 2023 Improving functionality and appearance with custom-made iris implants Managing iris defects can be challenging, whether they are congenital or acquired through traumatic events. When necessary, an iris implant can mimic a natural iris and help improve visual symptoms that have been affect[...] Oct. 14, 2023 Textbook review: Evolutionary analysis of pediatric eye movement disorders A scientific textbook by Michael C. Brodsky, M.D., an ophthalmologist at Mayo Clinic in Rochester, Minnesota, provides a comprehensive neurologic explanation for the unique eye movement disorders that afflict children w[...] Oct. 14, 2023 Diagnosis, clinical trials and treatments for inherited retinal diseases For people with inherited retinal diseases, timely diagnosis, counseling and resource discussions are imperative to improve quality of life. Depending on the condition, treatment may be available, often through clinical[...] Aug. 12, 2023 By the numbers: Mayo Clinic Ophthalmology Podcast The Mayo Clinic Ophthalmology Podcast series covers the latest and greatest discoveries in ophthalmology through the lens of an academic institution, Mayo Clinic. Aug. 04, 2023 Potential one-time gene therapy treatment for wet age-related macular degeneration Dr. Sophie J. Bakri, an ophthalmologist at Mayo Clinic in Rochester, Minnesota, performed the first subretinal gene therapy as part of a clinical study of RGX-314 as a potential one-time gene therapy for wet AMD. April 27, 2023 Thyroid Eye Disease Clinic offers customized, collaborative approach to treatment Mayo Clinic's Thyroid Eye Disease Clinic offers a collaborative approach that helps streamline diagnostic processes and treatment recommendations. April 27, 2023 Pediatric retina surgery program ensures patient-centered care Dr. Brittni A. Scruggs, an ophthalmologist at Mayo Clinic in Rochester, Minnesota, leads the effort to use the latest technology and research to provide comprehensive pediatric retina care. April 27, 2023 Fine-tuning cataract surgery: light adjustable lens Light Adjustable Lens is an innovative technology that allows physicians to design, trial and customize a patient's vision after cataract surgery. Oct. 01, 2022 Welcoming new ophthalmologist to Mayo Clinic Board-certified ophthalmologist Ashlie A. Bernhisel, M.D., has joined Ophthalmology at Mayo Clinic in Rochester, Minnesota. Oct. 01, 2022 New study assesses the risk of stroke before and after central retinal artery occlusion Mayo Clinic researchers analyzed population-based data to study the correlation between central retinal artery occlusion and incidence of ischemic stroke to evaluate the associated risk. Oct. 01, 2022 Mayo Clinic Ophthalmology Podcast Hosted by Erick D. Bothun, M.D., and Andrea A. Tooley, M.D., the Mayo Clinic Ophthalmology Podcast features guests from around the world to discuss ophthalmology and various subsets of medicine. July 27, 2022 Children diagnosed with type 2 diabetes, increased risk of developing vision-threatening retinopathy A retrospective study shows that children diagnosed with type 2 diabetes developed retinopathy after a shorter diabetes duration and at a higher rate than children with type 1 diabetes. July 27, 2022 Drusen phenotypes associated with advanced age-related macular degeneration Reticular pseudodrusen, basal laminar drusen and calcified drusen all showed a strong association with more-advanced stages of age-related macular degeneration, according to a Mayo Clinic study. The study also showed a [...] July 27, 2022 Reexamining the relationship among metabolic syndrome, CCT and ocular hypertension Mayo Clinic study shows that metabolic syndrome is associated with ocular hypertension. The results also suggest that this association may be related to increased central corneal thickness. March 12, 2022 Mobile platform obtains quantitative measurements of exophthalmos with variability similar to Hertel exophthalmometry A simple-to-use mobile application yields reliable, accurate measurements in a timely, efficient manner — and may be a suitable alternative when Hertel exophthalmometry is not available for measurement of globe po[...] March 12, 2022 Many ophthalmic irAEs can be treated without discontinuation of life-prolonging immunotherapy Ophthalmic immune-related adverse events (irAEs) associated with using immune checkpoint inhibitors (ICIs) are rare, but ophthalmologists need to recognize irAEs and un[...] March 12, 2022 Optic effect on peripheral retinal illumination holds implications for negative dysphotopsia Mayo Clinic researchers used ray-tracing analysis to compare the influence of 6.0 mm and 7.0 mm intraocular lens optic diameters on illumination of the peripheral retina. Jan. 07, 2022 Data and communication support individualized pediatric retinoblastoma program Evidence-based practices and communication with families are key to pediatric retinoblastoma care. Mayo Clinic physicians work collaboratively with one another, the patient's family and global data to advance retinoblas[...] Oct. 01, 2021 IPL-MGX improves dry eye symptoms more than MGX alone in treating ocular rosacea with dry eye Mayo Clinic offers intense pulsed light combined with meibomian gland expression to treat ocular rosacea and meibomian gland disease with dry eye symptoms successfully. Oct. 01, 2021 Patients may receive cataract surgery if diabetic macular edema is managed pre- and post-surgery A retrospective study indicates that patients with active diabetic macular edema and visually significant cataract can consider cataract surgery while maintaining an effective perioperative intravitreal anti-vascular en[...] Oct. 01, 2021 Netarsudil significantly reduces intraocular pressure in patients with primary open-angle glaucoma Mayo Clinic researchers have identified the mechanism of action for intraocular pressure (IOP) reduction by netarsudil in patients with primary open-angle glaucoma or ocular hypertension. July 20, 2021 Genomic sequencing shows promise in elucidating genetic causes of strabismus Next-generation genome sequencing approaches hold great promise in identifying rare variants associated with strabismus and elucidating the genetic causes of the disorder. July 20, 2021 Disease expression and familial transmission in Fuchs' endothelial dystrophy The Fuchs' endothelial corneal dystrophy (FECD) phenotype commonly occurs in individuals who do not harbor CTG18.1 expansion but are part of families with CTG18.1 expansion. July 20, 2021 Study supports the use of plaque imaging in the evaluation of patients with acute retinal artery occlusion Researchers found that patients with retinal artery occlusion (RAO) had higher prevalence of intraplaque hemorrhage (IPH). The presence of IPH was independently associated with ipsilateral RAO. April 20, 2021 Studies support Scheimpflug tomography's efficacy in predicting the prognosis of FECD Studies confirm that the presence of even one or two map features increased the probability of Fuchs' endothelial corneal dystrophy (FECD) progression independent of central corneal thickness. April 20, 2021 Fibrin hydrogels provide safe, degradable scaffolds for subretinal implantation Researchers report that an animal study demonstrates complete degradation of a surgically implanted fibrin scaffold within the subretinal space. April 20, 2021 Standardized prescribing guidelines reduce frequency and quantity of opioids prescribed Development of standardized opioid prescribing guidelines and discussion of postsurgical pain management reduced the overprescribing of opioids without increasing refill rates. March 20, 2021 Retinoblastoma: Specialized neuroradiology for optimal care Mayo Clinic's experienced specialists work to preserve the child's life, eye and sight. March 11, 2021 Regenerative approaches to improving corneal transplantation Mayo Clinic offers two partial-thickness corneal transplants for patients with diseased endothelial cells. Advancements in transplantation surgery make it possible to improve eyesight without removing the full thickness[...] May 01, 2020 Intravitreal anti-VEGF pharmacotherapy safe for treatment of diabetic macular edema Study offers further evidence of a relatively safe systemic risk profile for intravitreal anti-VEGF pharmacotherapy used for the treatment of patients with decreased vision secondary to center-involving DME. Sept. 14, 2019 Use of intraocular lenses relatively safe for treatment of cataracts in infants ages 7 to 24 months old The Toddler Aphakia and Pseudophakia Study (TAPS) evaluated concerns about adverse events, re-operations and refractive changes in infants who receive intraocular lens implantation for cataract. Sept. 14, 2019 Study supports increased risk of ischemic stroke in the peri-CRAO period Research supports that there is an increased risk of stroke around the time of central retinal artery occlusion (CRAO), especially if an embolic etiology of CRAO is diagnosed. Sept. 14, 2019 Study finds most conjunctival tumors benign with low risk of malignant transformation While most conjunctival tumors are benign with low risk of malignant transformation, researchers recommend subspecialty referrals in the setting of changing appearance or worrisome features. July 16, 2019 PedEyeQ assesses quality of life in children with eye conditions PedEyeQ comprehensive questionnaires can be used to assess two broad areas, eye-related quality of life and functional vision, in children of any age with any eye condition. July 16, 2019 Biopsy recommended for patients with clinical characteristics of IgG4-ROD Researchers recommend biopsy for patients who do not follow the usual clinical course of Graves' orbitopathy or have clinical characteristics of immunoglobulin G4-related ophthalmic disease (IgG4-ROD). July 16, 2019 Study identifies clinical phenotype, visual outcomes of MOG-IgG antibody optic neuritis Research supports that MOG-IgG positivity should be suspected if optic disk edema is moderate to severe at onset or if MRI shows optic nerve sheath involvement. April 13, 2019 Risk of primary open-angle glaucoma increases after vitreoretinal surgery Research supports an increased risk of late-onset, primary open-angle glaucoma (POAG) after vitrectomy and vitrectomy with scleral buckling, but not after scleral buckling alone. Researchers recommend more-frequent moni[...] April 13, 2019 New method classifies FECD severity: Tomographic evaluation of corneas for subclinical edema A new method of classifying Fuchs' endothelial corneal dystrophy (FECD) severity employs Scheimpflug tomography for preoperative assessment of corneas for the presence of subclinical edema. April 13, 2019 Optimal timing for intervention in congenital nasolacrimal duct obstruction A study of infants with congenital nasolacrimal duct obstruction (CNLDO) suggests that surgical intervention may be most appropriate in an early and narrow time frame: between ages 9 and 15 months. Feb. 01, 2019 Patients with central retinal artery occlusion require embolic work-ups Research published in Mayo Clinic Proceedings indicates symptomatic stroke, TIA or amaurosis fugax is common around the time of central retinal artery occlusion. Researchers recommend urgent embolic work-ups for those p[...] Sept. 21, 2018 Surgical treatment impacts health-related quality of life for patients with glaucoma Patients with glaucoma report poor health-related quality of life due to worse diplopia, lower mean deviation on visual field testing in either eye, decreased visual acuity in either eye, younger age, and previous glauc[...] Sept. 21, 2018 Ocular manifestations in post-transplant lymphoproliferative disorder: A case report Mayo subspecialists collaborated for successful treatment of an 8-year-old boy. After orthotopic heart transplantation, the boy exhibited bilateral ocular involvement in post-transplant lymphoproliferative disorder with[...] Aug. 21, 2018 Optic disk edema in GFAP meningoencephalitis may mimic papilledema Mayo specialists recommend testing cerebrospinal fluid glial fibrillary acidic protein (GFAP) autoantibodies in patients with unexplained meningoencephalitis. Their optic disk edema is more likely due to an inflammatory[...] Aug. 18, 2018 Fibrin hydrogels provide a scaffold for transplantation of RPE monolayers Research suggests that fibrin hydrogels may provide a long-lived scaffold for the differentiation of retinal pigment epithelium (RPE) from stem cells that can then be degraded under controlled circumstances after delive[...] Aug. 17, 2018 Incidence of pseudophakic intraocular lens exchange increases with incidence of cataract surgery Emerging indications of intraocular lens exchange, including unplanned refractive error and uveitis-glaucoma-hyphema syndrome from square-edged haptics in the ciliary sulcus, reflect changes in lens design and increasin[...] April 13, 2018 Research confirms the clinical characteristics of ocular sarcoidosis In a population-based study of the clinical characteristics of ocular involvement of sarcoidosis, eye symptoms were the first presentation that led to the diagnosis of systemic sarcoidosis in more than half of the patie[...] April 13, 2018 Psychological factors may impact quality of life after strabismus surgery Depressive symptoms, double vision and facial anomalies may impact patient-reported outcome measures after strabismus surgery. Research confirms the need to consider and address psychological factors and personality par[...] Oct. 13, 2017 Risk of serious complications increases for older adult patients treated with dacryocystorhinostomy for acquired nasolacrimal duct obstruction Research indicates that in patients age 80 and older, the rate of symptom resolution after dacryocystorhinostomy was significantly lower and the risk of serious complications was higher than that of younger patients. Oct. 13, 2017 Incidence of idiopathic intracranial hypertension parallels rising rate of obesity Obesity is a major risk factor for idiopathic intracranial hypertension (IIH). Research indicates that the incidence rates of obesity and IIH have increased steadily and in parallel since 1990. April 15, 2017 The causes of acquired 3rd nerve palsy A study using Rochester Epidemiology Project (REP) records demonstrates a higher incidence of microvascular and a lower incidence of aneurysmal third nerve palsies than previously reported in nonpopulation-based studies[...] Nov. 01, 2016 Eye in the Storm A clinician and investigators with Ophthalmology at Mayo Clinic in Rochester, Minnesota, team to learn how toxic RNA short-circuits corneal cells. May 01, 2014 Incidence and probability of progression to blindness due to open-angle glaucoma decreases dramatically New diagnostic and progression analysis tools and new therapies for intraocular pressure reduction have benefited individual patients. A Rochester Epidemiology Project-based study explores their effects on the rates of [...] Sept. 05, 2013 Cancer immunotherapy eradicates tumors from within Cancer immunotherapy cures tumor-burdened mice - Researchers used human DNA from melanoma cells delivered through the vector vesicular stomatitis virus to eradicate cancerous tumors in mice. Success is associated with t[...] Medical Professionals Ophthalmology News