Clinical Trials Below are current clinical trials.24 studies in Ophthalmology (open studies only). Filter this list of studies by location, status and more. A Study to Evaluate Advanced Ultrasound Techniques for Diagnosis of Giant Cell Arteritis Rochester, Minn. The purpose of this study is to find out if advanced ultrasound studies can be used to make a diagnosis of giant cell arteritis. Ultimately, we hope to be able to offer non-invasive diagnostic options as an alternative to biopsy to future patients who are being evaluated for giant cell arteritis. A Study to Evaluate Patient Reported Outcome Measures in Children with Eye Conditions Rochester, Minn. The objectives of this study are: To evaluate patient-reported quality of life and functional vision across the spectrum of pediatric eye conditions; To assess change in patient-reported quality of life and functional vision over time; To compare the impact of different treatments on quality of life and functional vision; To assess change in patient-reported quality of life and functional vision in response to treatment; To determine associations between quality of life / functional vision scores and specific clinical and demographic characteristics. A Study to Evaluate a Color Test for Patients with Optic Nerve Diseases Rochester, Minn. The purpose of this study is to evaluate the clinical utility of a quantitative test to measure how color saturation appears in patients with diseases of the optive nerve. A Study to Evaluate the Effectiveness of Critical Flicker Fusion in Distinguishing Different Causes of Altered Vision Rochester, Minn. The purpose of this study is to evaluate the effectiveness of the critical flicker fusion device in distinguishing different kinds of optic neuropathy and visual perception. Exparel Injection for Postoperative Orbital Pain Rochester, Minn. After surgery to remove the eye, either by enucleation or evisceration, patients have variable levels of pain for several postoperative days. Some patients have almost no discomfort while others require significant amounts of oral narcotics and report pain of 10 out of 10 on a numerical rating scale. The current operative standard is to infiltrate the eye socket with 0.5% bupivacaine during surgery leading to several hours of postoperative analgesia. In 2011, Pacira Pharmaceuticals released a bupivacaine liposomal injectable suspension (Exparel, 1.3%) which offers sustained release of bupivacaine giving postoperative pain control for up to 72 hours. This medication has been used in numerous surgeries including inguinal hernia repair, hemorrhoidectomy, bunionectomy, breast reconstruction, and orthopedic surgery, and the literature reports improved pain control, decreased use of oral opioids, and increased patient satisfaction. There are no reports of the use of Exparel in the ophthalmic literature. The investigators propose a randomized, controlled trial to compare the postoperative pain control offered by sustained release bupivacaine to that offered by standard plain bupivacaine after enucleation or evisceration. A Study to Evaluate Optical Coherence Tomography (OCT) and OCT Angiography (OCTA) Imaging In Supine Patient Rochester, Minn. The purpose of this study is to determine if a relay lens and right angle mirror can be used in conjunction with an FDA-approved optical coherence tomography (OCT) unit to allow imaging in supine patients. Intraocular Pressure in Ocular Hypertensives with Scleral Lens Wear Rochester, Minn. The purpose of this study is to determine if short-term wear of a scleral contact lens will raise intraocular pressure in ocular hypertensive patients. A Study Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles Plus Patching for Amblyopia in Children 3 to < 13 Years Old Rochester, Minn. The purpose of this study is to determine whether simultaneous treatment with spectacles and patching has an equivalent VA outcome compared with sequential treatment, first with spectacles alone, followed by patching (if needed), for previously untreated amblyopia in children 3 to < 13 years of age. A Study to Assess for Changes in Optic Nerve Structure and Function due to Changes in Cerebrospinal Fluid Pressure Rochester, Minn. The purpose of this study is to assess for changes in the structure and function of the optic nerve caused by changes in cerebrospinal fluid pressure. A Study to Evaluate Visual Function in Fuchs Endothelial Corneal Dystrophy Rochester, Minn. The purpose of this study is to determine visual function in patients with Fuchs Endothelial Corneal Dystrophy (FECD) to understand when in the course of disease patients are affected by compromised vision. Pagination Clinical studies Go to page 11 Go to page 22 Go to page 33 NextNext Page Medical Professionals Ophthalmology Clinical Trials