Ophthalmology

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study to Evaluate Patient Reported Outcome Measures in Children with Eye Conditions

   Rochester, Minn.

   The objectives of this study are:

   • To evaluate patient-reported quality of life and functional vision across the spectrum of pediatric eye conditions;
   • To assess change in patient-reported quality of life and functional vision over time;
   • To compare the impact of different treatments on quality of life and functional vision;
   • To assess change in patient-reported quality of life and functional vision in response to treatment;
   • To determine associations between quality of life / functional vision scores and specific clinical and demographic characteristics.

2. A Study to Evaluate a Color Test for Patients with Optic Nerve Diseases

   Rochester, Minn.

   The purpose of this study is to evaluate the clinical utility of a quantitative test to measure how color saturation appears in patients with diseases of the optive nerve.

3. A Study to Evaluate Optical Coherence Tomography (OCT) and OCT Angiography (OCTA) Imaging In Supine Patient

   Rochester, Minn.

   The purpose of this study is to determine if a relay lens and right angle mirror can be used in conjunction with an FDA-approved optical coherence tomography (OCT) unit to allow imaging in supine patients.

4. A Study Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles Plus Patching for Amblyopia in Children 3 to < 13 Years Old

   Rochester, Minn.

   The purpose of this study is to determine whether simultaneous treatment with spectacles and patching has an equivalent VA outcome compared with sequential treatment, first with spectacles alone, followed by patching (if needed), for previously untreated amblyopia in children 3 to < 13 years of age.

    

    

5. A Study to Evaluate Visual Function in Fuchs Endothelial Corneal Dystrophy

   Rochester, Minn.

   The purpose of this study is to determine visual function in patients with Fuchs Endothelial Corneal Dystrophy (FECD) to understand when in the course of disease patients are affected by compromised vision.

6. Evaluating Optic Nerve Disease with OCT Angiography

   Rochester, Minn.

   The purpose of this study is to determine if optical coherence tomography (OCT) angiography is able to distinguish different causes of optic neuropathy.

7. A Study to Analyze Waste Specimens from the Eye After Surgery

   Rochester, Minn.

   The purpose of this study is to learn about cell function in different tissues of the eye in various ocular diseases via transcriptomics in the Mayo Clinic laboratory.

8. Collaborative Study on Optic Neuritis and Autoantibodies Affecting the Eye

   Rochester, Minn.

   The study proposes to form a consortium of autoimmunity of the optic nerve with the goal of improving diagnosis and treatment of these conditions. 

9. A Study to Evaluate the Use of Micropulse Trans-Scleral Cyclophotocoagulation Laser (MP-TSCPC) for Glaucoma Patients

   Jacksonville, Fla.

   The purpose of this study is to evaluate the clinical outcomes of the Micropulse Trans-Scleral Cyclophotocoagulation Laser (MPTSCPC) after 1 day, 1 week,1 month, 3 months, 6 months and one year of follow-up. Its primary objective is to conduct a prospective observational study on the efficacy of using MP-TSCPC to treat glaucoma patients.

10. A Natural History Observation and Registry Study of Macular Telangiectasia Type 2: The MacTel Study

    Rochester, Minn.

    The purpose of this study is to develop a Registry of participants with MacTel Type 2 (as confirmed by the Reading Center) who may agree to be contacted for inclusion in future clinical trials. The Registry participants include new participants and participants from the NHO, Genetic I and Genetics II studies who agree to continue to participate. 

    The second objective is to continue to identify whether there is a genetic link associated with MacTel Type 2. All participants who have not previously provided a blood sample will be given the option to provide a blood sample for genetic sequencing.