Angiotensin II receptor blockers

Angiotensin II receptor blockers treat high blood pressure. Find out when your doctor may prescribe them.

By Mayo Clinic Staff

Angiotensin II receptor blockers help relax your veins and arteries to lower your blood pressure and make it easier for your heart to pump blood.

Angiotensin is a chemical in your body that narrows your blood vessels. This narrowing can increase your blood pressure and force your heart to work harder.

Angiotensin II receptor blockers block the action of angiotensin II. As a result, the medication allows your veins and arteries to widen (dilate).

Examples of angiotensin II receptor blockers

Several angiotensin II receptor blockers are available. Which one is best for you depends on your health and the condition being treated.

Examples of angiotensin II receptor blockers include:

  • Azilsartan (Edarbi)
  • Candesartan (Atacand)
  • Eprosartan
  • Irbesartan (Avapro)
  • Losartan (Cozaar)
  • Olmesartan (Benicar)
  • Telmisartan (Micardis)
  • Valsartan (Diovan)

When angiotensin II receptor blockers are used

In addition to treating high blood pressure, angiotensin II receptor blockers may prevent, treat or improve symptoms in people who have:

  • Chronic kidney diseases
  • Heart failure
  • Kidney failure in diabetes

Side effects

Possible side effects of angiotensin II blockers can include:

  • Dizziness
  • Higher than normal potassium levels in the blood (hyperkalemia)
  • Swelling of the skin due to a buildup of fluid (angioedema)

Some people taking the angiotensin II receptor blocker olmesartan have reported intestinal problems. Talk to your doctor if you develop severe diarrhea or lose a lot of weight while taking this medication.

Don't take angiotensin II receptor blockers if you're pregnant or plan to become pregnant because the drugs can harm a developing fetus.

Get the latest health information from Mayo Clinic’s experts.

Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health.

To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail.

Aug. 13, 2021 See more In-depth

See also

  1. Medication-free hypertension control
  2. 6 surprising signs you may have obstructive sleep apnea
  3. After a flood, are food and medicines safe to use?
  4. Alcohol: Does it affect blood pressure?
  5. Alpha blockers
  6. Amputation and diabetes
  7. Angiotensin-converting enzyme (ACE) inhibitors
  8. Antiphospholipid syndrome
  9. Anxiety: A cause of high blood pressure?
  10. Arteriosclerosis / atherosclerosis
  11. Artificial sweeteners: Any effect on blood sugar?
  12. AskMayoMom Pediatric Urology
  13. Beta blockers
  14. Beta blockers: Do they cause weight gain?
  15. Beta blockers: How do they affect exercise?
  16. Birth control pill FAQ
  17. Blood glucose meters
  18. Blood glucose monitors
  19. Blood pressure: Can it be higher in one arm?
  20. Blood pressure chart
  21. Blood pressure cuff: Does size matter?
  22. Blood pressure: Does it have a daily pattern?
  23. Blood pressure: Is it affected by cold weather?
  24. Blood pressure medication: Still necessary if I lose weight?
  25. Blood pressure medications: Can they raise my triglycerides?
  26. Blood pressure readings: Why higher at home?
  27. Blood pressure test
  28. Blood pressure tip: Get more potassium
  29. Blood pressure tip: Get off the couch
  30. Blood pressure tip: Know alcohol limits
  31. Blood pressure tip: Stress out no more
  32. Blood pressure tip: Watch the caffeine
  33. Blood pressure tip: Watch your weight
  34. Blood sugar levels can fluctuate for many reasons
  35. Blood sugar testing: Why, when and how
  36. Bone and joint problems associated with diabetes
  37. How kidneys work
  38. Build resilience to better handle diabetes
  39. Bump on the head: When is it a serious head injury?
  40. Caffeine and hypertension
  41. Calcium channel blockers
  42. Calcium supplements: Do they interfere with blood pressure drugs?
  43. Can whole-grain foods lower blood pressure?
  44. Caring for a loved one with diabetes
  45. Central-acting agents
  46. Choosing blood pressure medications
  47. Chronic daily headaches
  48. Chronic kidney disease
  49. Coarctation of the aorta
  50. COVID-19 and high blood pressure
  51. COVID-19: Who's at higher risk of serious symptoms?
  52. Cushing syndrome
  53. DASH diet
  54. DASH diet
  55. DASH diet: Recommended servings
  56. DASH diet: Shopping and cooking tips
  57. Diabetes
  58. Diabetes and dental care
  59. Diabetes and depression: Coping with the two conditions
  60. Diabetes and exercise: When to monitor your blood sugar
  61. Diabetes and fasting: Can I fast during Ramadan?
  62. Diabetes and foot care
  63. Diabetes and Heat
  64. Diabetes and menopause
  65. Diabetes and summer: How to beat the heat
  66. Diabetes and travel: Planning is key
  67. Diabetes and electric blankets
  68. 10 ways to avoid diabetes complications
  69. Diabetes diet: Should I avoid sweet fruits?
  70. Diabetes diet: Create your healthy-eating plan
  71. Diabetes foods: Can I substitute honey for sugar?
  72. Diabetes and liver
  73. Diabetes management: Does aspirin therapy prevent heart problems?
  74. Diabetes management: How lifestyle, daily routine affect blood sugar
  75. Diabetes: Eating out
  76. Diabetes nutrition: Sweets
  77. Diabetes symptoms
  78. Diabetes treatment: Can cinnamon lower blood sugar?
  79. Using insulin
  80. Diuretics
  81. Diuretics: A cause of low potassium?
  82. Diuretics: Cause of gout?
  83. Dizziness
  84. Do infrared saunas have any health benefits?
  85. Do you know your blood pressure?
  86. Does obstructive sleep apnea increase my risk for Alzheimer's disease?
  87. Drug addiction (substance use disorder)
  88. High blood pressure and exercise
  89. Fibromuscular dysplasia
  90. Free blood pressure machines: Are they accurate?
  91. Home blood pressure monitoring
  92. Glomerulonephritis
  93. Glycemic index: A helpful tool for diabetes?
  94. Guillain-Barre syndrome
  95. Headaches 101: Know your type
  96. Headaches and hormones
  97. Headaches: Treatment depends on your diagnosis and symptoms
  98. Is chocolate healthy?
  99. Herbal supplements and heart drugs
  100. High blood pressure (hypertension)
  101. High blood pressure and cold remedies: Which are safe?
  102. High blood pressure and sex
  103. High blood pressure: Can you prevent it?
  104. High blood pressure dangers
  105. How opioid addiction occurs
  106. How to get used to positive airway pressure (PAP) therapy
  107. How to tell if a loved one is abusing opioids
  108. How to use opioids safely
  109. Hunter syndrome
  110. Hypertensive crisis: What are the symptoms?
  111. Hypothermia
  112. IgA nephropathy (Berger's disease)
  113. Improve obstructive sleep apnea with physical activity
  114. Insulin and weight gain
  115. Insulin therapy options
  116. Intensive insulin therapy
  117. Intracranial hematoma
  118. Isolated systolic hypertension: A health concern?
  119. Kratom for opioid withdrawal
  120. L-arginine: Does it lower blood pressure?
  121. Late-night eating: OK if you have diabetes?
  122. Preventing lead exposure
  123. Lead poisoning
  124. Living better with obstructive sleep apnea
  125. Low-phosphorus diet: Helpful for kidney disease?
  126. Making sense of obstructive sleep apnea treatments
  127. Diabetes and carbs
  128. Medications and supplements that can raise your blood pressure
  129. Menopause and high blood pressure: What's the connection?
  130. Molar pregnancy
  131. MRI: Is gadolinium safe for people with kidney problems?
  132. New Test for Preeclampsia
  133. Nighttime headaches: Relief
  134. Nosebleeds
  135. Sleep apnea, obstructive
  136. Obstructive Sleep Apnea
  137. Obstructive sleep apnea: How quickly will I see results from treatment?
  138. Opioids and other drugs: What to watch for
  139. Pain Management
  140. Pheochromocytoma
  141. Picnic Problems: High Sodium
  142. Pituitary tumors
  143. Polycystic kidney disease
  144. Polypill: Does it treat heart disease?
  145. Porphyria
  146. Postpartum preeclampsia
  147. Preeclampsia
  148. Prescription drug abuse
  149. Primary aldosteronism
  150. Pulse pressure: An indicator of heart health?
  151. Mayo Clinic Minute: Rattlesnakes, scorpions and other desert dangers
  152. Reactive hypoglycemia: What can I do?
  153. Reading food labels
  154. Renal diet for vegetarians
  155. Resperate: Can it help reduce blood pressure?
  156. Sample DASH menus
  157. Scorpion sting
  158. Secondary hypertension
  159. Serotonin syndrome
  160. Service dogs assist with diabetes care
  161. Sleep deprivation: A cause of high blood pressure?
  162. Sleep tips
  163. Vegetable recipes
  164. Blood sugar testing
  165. Snoring
  166. Snoring solution: Sleep on your side
  167. Spider bites
  168. Stress and headaches: Stop the cycle
  169. Stress and high blood pressure
  170. Symptom Checker
  171. Takayasu's arteritis
  172. Tapering off opioids: When and how
  173. Tetanus
  174. Tetanus shots: Is it risky to receive 'extra' boosters?
  175. The dawn phenomenon: What can you do?
  176. Tips for cutting costs of blood glucose test strips
  177. Infographic: Transplant for Polycystic Kidney Disease
  178. Treating pain: When is an opioid the right choice?
  179. Vasodilators
  180. Vegetarian diet: Can it help me control my diabetes?
  181. Vesicoureteral reflux
  182. Video: Heart and circulatory system
  183. How diabetes affects your blood sugar
  184. How to measure blood pressure using a manual monitor
  185. How to measure blood pressure using an automatic monitor
  186. Obstructive sleep apnea: What happens?
  187. What is blood pressure?
  188. Can having vitamin D deficiency cause high blood pressure?
  189. Weightlifting: Bad for your blood pressure?
  190. What are opioids and why are they dangerous?
  191. What's your high blood pressure risk?
  192. White coat hypertension
  193. Wrist blood pressure monitors: Are they accurate?
  194. Effectively managing chronic kidney disease