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Mayo Clinic has one of the largest and most experienced practices in the United States,
with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work
together to ensure quality care and successful recovery.
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- Rochester, MN
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Mayo Clinic scientists, doctors and surgeons develop liver transplant insights and innovations that make transplants safer and available to more people. They are actively involved in conducting laboratory studies, clinical trials and other research on every aspect of conditions related to liver transplants.
Here are a few examples:
- Bioartificial liver. This innovation helps patients cope as they await a donor liver. Developed by Mayo Clinic doctors and researchers, new bioartificial livers use living cells from pig livers to filter a patient's blood in a process similar to that of kidney dialysis. The device is being tested before it becomes available in clinics and hospitals.
- Magnetic resonance elastography. This innovative technology was developed by Mayo Clinic doctors and researchers as a noninvasive way to test for liver scarring. Someday it may reduce the need for liver biopsies in people with liver disease.
- Immunosuppressive medications. This research examines the effect of antibody-mediated injury in liver-kidney transplants and how doing a multiorgan transplant may actually result in better outcomes.
- Maximizing organ donors. Transplant physicians found that people with liver cancer have the same beneficial outcomes using organs donated by patients who died of cardiac death rather than brain death.
- Cell therapies for liver disease. This research offers potential new treatments for several liver diseases and may improve the success of liver transplantation.
- Triage system. Mayo Clinic researchers originally proposed, designed and tested the Model for End-Stage Liver Disease (MELD). This system prioritizes people waiting for a transplant based on the severity of their condition and how urgently they may need a transplant.
Read more about the many liver transplant research studies supported by the Transplant Research Center.
See a list of publications about liver transplant by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.
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Liver transplant care at Mayo Clinic
June 02, 2021
- AskMayoExpert. Liver transplant. Mayo Clinic; 2017.
- Liver transplant. American Liver Foundation. https://liverfoundation.org/for-patients/about-the-liver/the-progression-of-liver-disease/liver-transplant/#what-you-should-know-about-liver-transplantation. Accessed Oct. 14, 2019.
- Liver transplant. National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/liver-disease/liver-transplant. Accessed Oct. 14, 2019.
- Waiting for your transplant. UNOS Transplant Living. https://transplantliving.org/before-the-transplant/waiting-for-your-transplant/. Accessed Oct. 14, 2019.
- Busuttil RW, et al., eds. Donor selection and management. In: Transplantation of the Liver. 3rd ed. Saunders Elsevier; 2015. https://www.clinicalkey.com. Accessed Oct, 14, 2019.
- Side effects. UNOS Transplant Living. https://transplantliving.org/after-the-transplant/preventing-rejection/side-effects/. Accessed Oct.14, 2019.
- Dove LM, et al. Liver transplantation in adults: Patient selection and pretransplantation evaluation. https://www.uptodate.com/contents/search. Accessed Oct. 14, 2019.
- Bambha K, et al. Model for end-stage liver disease (MELD). https://www.uptodate.com/contents/search. Accessed Oct. 14, 2019.
- Cotler S. Living donor liver transplantation. https://www.uptodate.com/contents/search. Accessed Oct. 14, 2019.
- Schenck D, et al. Ethical analysis and policy recommendations regarding domino liver transplantation. Transplantation. 2018; doi:10.1097/TP.0000000000002095.
- Kim WR, et al. OPTN/SRTR 2017 annual data report: Liver. American Journal of Transplantation. 2019; doi:10.1111/ajt.15276.
- Pardo MC, et al., eds. Organ transplantation. In: Basics of Anesthesia. 7th ed. Elsevier; 2018. https://www.clinicalkey.com. Accessed Oct. 15, 2019.
- Rumack CM, et al., eds. Organ transplantation. In: Diagnostic Ultrasound. 5th ed. Elsevier; 2018. https://www.clinicalkey.com. Accessed Oct. 15, 2019.
- Preventing rejection. UNOS Transplant Living. https://transplantliving.org/after-the-transplant/preventing-rejection/. Accessed Oct. 15, 2019.
- Why join a support group. UNOS Transplant Living. https://transplantliving.org/community/support-groups/. Accessed Oct. 15, 2019.
- Liver transplant. Scientific Registry of Transplant Recipients. http://www.srtr.org. Accessed Oct. 15, 2019.
- Glorioso JM, et al. Pivotal preclinical trial of the spheroid reservoir bioartificial liver. Journal of Hepatology. 2015; doi:10.1016/j.jhep.2015.03.021.
- Yu Y, et al. Cell therapies for liver diseases. Liver Transplantation. 2012; doi:10.1002/lt.22467.
- Taner T, et al. Decreased chronic cellular and antibody-mediated injury in the kidney following simultaneous liver-kidney transplantation. Kidney International. 2016; doi:10.1016/j.kint.2015.10.016.
- De Assuncao TM, et al. Development and characterization of human-induced pluripotent stem cell-derived cholangiocytes. Laboratory Investigation. 2015; doi:10.1038/labinvest.2015.51.
- Croome KP, et al. The use of donation after cardiac death allografts does not increase recurrence of hepatocellular carcinoma. American Journal of Transplantation. 2015; doi:10.1111/ajt.13306.
- Find a transplant hospital. UNOS Transplant Living. https://transplantliving.org/before-the-transplant/find-transplant-hospital/. Accessed Oct. 15, 2019.
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