Overview

A liver hemangioma (he-man-jee-O-muh) is a noncancerous (benign) mass in the liver made up of a tangle of blood vessels. Also known as hepatic hemangiomas or cavernous hemangiomas, these liver masses are common and are estimated to occur in up to 20% of the population.

Liver hemangioma

Liver hemangioma

A liver hemangioma is a noncancerous (benign) mass in the liver. A liver hemangioma is made up of a tangle of blood vessels.

Most cases of liver hemangiomas are discovered during an imaging study done for some other condition. People who have a liver hemangioma rarely experience signs and symptoms and typically don't need treatment.

It may be unsettling to know you have a mass in your liver, even if it's a benign mass. However, there's no evidence that an untreated liver hemangioma can lead to liver cancer.


Symptoms

In most cases, a liver hemangioma doesn't cause any signs or symptoms.

The liver

The liver

The liver is your largest internal organ. About the size of a football, it's located mainly in the upper right portion of your abdomen, beneath the diaphragm and above your stomach.

When a liver hemangioma causes signs and symptoms, they may include:

  • Pain in the upper right abdomen
  • Feeling full after eating only a small amount of food (early satiety)
  • Nausea
  • Vomiting

However, these symptoms are nonspecific and in most instances are due to something else even if you have a liver hemangioma, as these tend to be asymptomatic.


When to see a doctor

Make an appointment with your doctor if you experience any persistent signs and symptoms that worry you.


Causes

It's not clear what causes a liver hemangioma to form. Doctors believe liver hemangiomas are present at birth (congenital).

A liver hemangioma usually occurs as a single abnormal collection of blood vessels that is less than about 1.5 inches (about 4 centimeters) wide. Occasionally liver hemangiomas can be larger or occur in multiples. Large hemangiomas can occur in young children, but this is rare.

In most people, a liver hemangioma will never grow and never cause any signs and symptoms. But in a small number of people, a liver hemangioma will grow to cause symptoms and require treatment. It's not clear why this happens.


Risk factors

Factors that can increase the risk that a liver hemangioma will be diagnosed include:

  • Your age. A liver hemangioma can be diagnosed at any age, but it's most commonly diagnosed in people ages 30 to 50.
  • Your sex. Women are more likely to be diagnosed with a liver hemangioma than are men.
  • Pregnancy. Women who have been pregnant are more likely to be diagnosed with a liver hemangioma than women who have never been pregnant. It's believed the hormone estrogen, which rises during pregnancy, may play a role in liver hemangioma growth.
  • Hormone replacement therapy. Women who use hormone replacement therapy for menopausal symptoms may be more likely to be diagnosed with a liver hemangioma than women who do not.

Complications

Women who have been diagnosed with liver hemangiomas face a risk of complications if they become pregnant. The female hormone estrogen, which increases during pregnancy, is believed to cause some liver hemangiomas to grow larger.

Very rarely, a growing hemangioma can cause signs and symptoms that may require treatment, including pain in the upper right quadrant of the abdomen, abdominal bloating or nausea. Having a liver hemangioma doesn't mean you can't become pregnant. However, discussing the possible complications with your doctor can help you make a more informed choice.

Medications that affect hormone levels in your body, such as birth control pills, could cause an increase in size and complications if you've been diagnosed with a liver hemangioma. But this is controversial. If you're considering this type of medication, discuss the benefits and risks with your doctor.


Sep 11, 2021

  1. Feldman M, et al., eds. Hepatic tumors and cysts. In: Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 11th ed. Elsevier; 2021.https://www.clinicalkey.com. Accessed July 16, 2021.
  2. Cameron AM, et al. Management of liver hemangiomas. In: Current Surgical Therapy. 13th ed. Elsevier; 2020. https://www.clinicalkey.com. Accessed July 16, 2021.
  3. Curry MP. Hepatic hemangioma. https://www.uptodate.com/contents/search. Accessed July 16, 2021.
  4. Benign liver tumors. Merck Manual Professional Version. https://www.merckmanuals.com/professional/hepatic-and-biliary-disorders/liver-masses-and-granulomas/benign-liver-tumors. Accessed July 16, 2021.
  5. Khanna S (expert opinion). Mayo Clinic. July 18, 2021.

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