A stuffy nose from a cold is a common cause for a partial, brief loss of smell. A polyp or swelling inside the nose can lead to a loss of smell. Aging can cause a loss of smell, especially after age 60.

What is smell?

The nose and an area in the upper throat have special cells, called receptors, that discern odors. These receptors send a message to the brain about each smell. The brain then figures out what the smell is.

Any problem along the way can affect the sense of smell. Problems can include a stuffy nose; something that blocks the nose; swelling, called inflammation; nerve damage; or an issue with how the brain works.

Problems with the inner lining of the nose

Conditions that cause congestion or other issues inside the nose may include:

  1. Acute sinusitis
  2. Chronic sinusitis
  3. Common cold
  4. Coronavirus disease 2019 (COVID-19)
  5. Hay fever
  6. Influenza (flu)
  7. Nonallergic rhinitis
  8. Smoking

Blockages in the inside of the nose, called the nasal passages

Conditions that block the flow of air through the nose can include:

  1. Nasal polyps
  2. Tumors

Damage to your brain or nerves

The following can cause damage to the nerves to the area of the brain that picks up smells or to the brain itself to:

  1. Aging
  2. Alzheimer's disease
  3. Being around toxic chemicals, such as those used in solvents
  4. Brain aneurysm
  5. Brain surgery
  6. Brain tumor
  7. Diabetes
  8. Huntington's disease
  9. Hypothyroidism (underactive thyroid)
  10. Kallmann's syndrome (a rare genetic condition)
  11. Korsakoff's psychosis (a brain condition caused by the lack of vitamin B-1, also called thiamin)
  12. Lewy body dementia
  13. Medicines (such as some for high blood pressure, some antibiotics and antihistamines, and some nasal sprays)
  14. Multiple sclerosis
  15. Parkinson's disease
  16. Poor nutrition (such as too little zinc or vitamin B-12 in the diet)
  17. Pseudotumor cerebri (idiopathic intracranial hypertension)
  18. Radiation therapy
  19. Rhinoplasty and other surgeries of the nose
  20. Traumatic brain injury

Causes shown here are commonly associated with this symptom. Work with your doctor or other health care professional for an accurate diagnosis.

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June 22, 2026

See also

  1. Bardet-Biedl syndrome (BBS)
  2. Can vitamin D protect against coronavirus disease 2019 (COVID-19)?
  3. Chronic sinusitis
  4. Coronavirus disease 2019 (COVID-19)
  5. Coronavirus: What is it and how can I protect myself?
  6. COVID-19 and pets: Can dogs and cats get COVID-19?
  7. COVID-19 and your mental health
  8. COVID-19 drugs: Are there any that work?
  9. COVID-19 in babies and children
  10. COVID-19 travel advice
  11. COVID-19 vaccines for kids: What you need to know
  12. COVID-19 vaccines: Get the facts
  13. COVID-19 variants
  14. COVID-19 vs. flu: Similarities and differences
  15. COVID-19, cold, allergies and the flu: What are the differences?
  16. COVID-19: Who's at higher risk of serious symptoms?
  17. CPA tumor overview
  18. Debunking COVID-19 myths
  19. Different types of COVID-19 vaccines: How they work
  20. Fight coronavirus (COVID-19) transmission at home
  21. Herd immunity and COVID-19: What you need to know
  22. How do COVID-19 antibody tests differ from diagnostic tests?
  23. How well do face masks protect against COVID-19?
  24. Is hydroxychloroquine a treatment for COVID-19?
  25. Long COVID: Lasting effects of COVID-19
  26. Loss of taste and smell: Natural with aging?
  27. Mayo Clinic Minute: How dirty are common surfaces?
  28. Mayo Clinic Minute: You're washing your hands all wrong
  29. Nasal polyps
  30. Pregnancy and COVID-19: What are the risks?
  31. Safe outdoor activities during the COVID-19 pandemic
  32. Safety tips for attending school during COVID-19
  33. Sex and COVID-19
  34. Skull base tumors
  35. Treating COVID-19 at home: Care tips for you and others
  36. Unusual symptoms of coronavirus