Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people. In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals, or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Appointments can often be arranged quickly — sometimes within two business days. To request an appointment with a brain tumor specialist, please call 507-284-2193 (Minnesota), 904-953-0818 (Florida), or 480-301-4193 (Arizona).

U.S. patients

Online requests

Telephone requests

Mayo Clinic's campus in Phoenix/Scottsdale, Arizona

Central Appointment Office

  1. 480-301-8484
  2. 8 a.m. to 5 p.m.
  3. Mountain time
  4. Monday through Friday
Mayo Clinic's campus in Jacksonville, Florida

Central Appointment Office

  1. 904-953-0853
  2. 8 a.m. to 5 p.m.
  3. Eastern time
  4. Monday through Friday
Mayo Clinic's campus in Rochester, Minnesota

Central Appointment Office

  1. 507-538-3270
  2. 7 a.m. to 6 p.m.
  3. Central time
  4. Monday through Friday
Mayo Clinic Children's Center

Central Appointment Office

  1. 855-MAYO-KID (855-629-6543, toll-free)
  2. 7 a.m. to 6 p.m.
  3. Central time
  4. Monday through Friday

Teamwork, experience and technology

The Mayo Clinic Brain Tumor Program — available at the clinic's campuses in Arizona, Florida and Minnesota — offers personalized, comprehensive, expert care to people with brain tumors. If you have a serious, complex or rare brain tumor condition, such as glioma, meningioma, pituitary tumors, skull base tumors or brain metastases, you'll find exactly the care you need here. Your care team is dedicated to matching you with the medical or surgical team that best fits your unique situation. This includes helping to select which clinic location is the most convenient.

The Mayo Clinic Brain Tumor Program brings together teamwork, experience and innovative technologies to achieve the best outcome possible for you. Your care team is made up of specialists who work together to develop an individualized treatment plan.

At its campus in Minnesota, the clinic provides expert care for children with brain tumors. Pediatric neuro-oncologists work with a team of specialists to diagnose and treat pediatric brain tumors and provide children with the personalized treatment they require.

A team approach, focused on you

Your Mayo Clinic brain tumor team may include specialists from neuro-oncology, neurosurgery, neuro-ophthalmology, neuropathology, neuroradiology, radiation oncology, medical oncology, endocrinology, otorhinolaryngology/head and neck surgery, and other areas as needed.

Having all this expertise in a single place, focused on you, means that you're not just getting one opinion. Your care is discussed among team members, your test results are available quickly and appointment schedules are coordinated. The most highly specialized experts in the world are working with you. What might take weeks or even months to accomplish elsewhere can typically be done in a matter of days at Mayo Clinic.

You also have access to supportive therapy during and after brain tumor treatment to help you feel better. These services include integrative medicine, palliative care, rehabilitation, psychotherapy and support groups. Talk with your doctor about these options and how they might help you live with the physical and emotional side effects of brain tumor treatment.

The right brain tumor care, the first time

Your expert care team is committed to making sure you receive the right care the first time. Successful treatment starts with an accurate diagnosis. You may undergo several tests so that your doctors can identify exactly what's causing your signs and symptoms and determine the best treatment for you. Whether surgery is an option depends on the location of the tumor, how fast it's growing, how it's entwined with healthy tissue, and how likely you are to respond to other therapies, such as radiation or medication.

Mayo Clinic's brain tumor teams use innovative and advanced imaging technologies and tools, including high-powered (7-tesla) magnetic resonance imaging, PET scanning and molecular diagnostics, a type of genetic testing. Molecular diagnostics is an individualized medicine approach that analyzes the DNA of a tumor. This testing helps doctors predict which treatment options will work on specific brain tumor types.

Precision treatment options include targeted drug therapy, intensity-modulated radiation therapy, lasers, computer-assisted brain surgery, stereotactic radiosurgery and proton therapy. Proton therapy delivers targeted doses of radiation to tumors while sparing healthy tissue and reducing the risk of side effects.

Mayo Clinic is one of the few centers in the country to offer awake brain surgery. This procedure helps certain people who have been told they have an inoperable brain tumor. People who have a brain tumor removed with this advanced approach often experience reduced hospital stays, a lower expected mortality rate and shorter recovery times. Many people who undergo brain tumor surgery at Mayo Clinic leave the hospital in one or two days.

Research: Innovation to treatment faster

Our brain tumor physicians and scientists are committed to researching innovative diagnostic and treatment options that improve people's lives. Research avenues include laboratory studies, mathematical modeling and clinical trials. People whose brain tumors haven't responded to treatment may be eligible for clinical trials that are testing new approaches.

One of the many new tools developed by Mayo Clinic doctors is now widely used to help people with brain tumors. It's called magnetic resonance elastography (MRE) and slip interface imaging, which provides doctors with vital information about the firmness and adhesion of brain tumors. This information affects their choice of surgical approach and timing, which in turn may reduce the risk of complications and the need for follow-up surgeries.

Your doctors will talk with you about the tests and procedures that are right for you. Not all services are available at each location. Please confirm when you request an appointment.

Mayo Clinic doctors who treat people with brain tumors have expertise in a many complex and serious conditions, including:

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

Find doctors and medical staff:


Neurology and oncology

  1. Maciej M. Mrugala, M.D., Ph.D.
  2. Alyx B. Porter, M.D.


  1. Bernard R. Bendok, M.D.
  2. Chandan Krishna, M.D.
  3. Mark K. Lyons, M.D.
  4. Naresh P. Patel, M.D.
  5. Richard S. Zimmerman, M.D.


  1. Dona E. Locke, Ph.D.

Radiation oncology

  1. Jonathan B. Ashman, M.D., Ph.D.
  2. Sameer R. Keole, M.D.
  3. Steven E. Schild, M.D.
  4. Terence T. Sio, M.D., M.S.
  5. Sujay A. Vora, M.D.


  1. Leland S. Hu, M.D.



Neuro-critical care





  • Mark E. Jentoft, M.D.





Otorhinolaryngology (ENT)/head and neck surgery

Radiation oncology


Medical oncology

  1. Evanthia Galanis, M.D.
  2. Sani H. Kizilbash, M.D., M.P.H.
  3. Ciara O'Sullivan, M.B., B.Ch.
  4. Steven I. Robinson, M.B.B.S.
  5. Michael W. Ruff, M.D.
  6. Joon H. Uhm, M.D.

Neurology and neuro-oncology

  1. Ivan (Darin) D. Carabenciov, M.D.
  2. Daniel H. Lachance, M.D.
  3. Michael W. Ruff, M.D.
  4. Joon H. Uhm, M.D.


  1. Edward S. Ahn, M.D.
  2. John L. D. Atkinson, M.D.
  3. Terence (Terry) C. Burns, M.D., Ph.D.
  4. Mohamad Bydon, M.D.
  5. Michelle (M. J.) J. Clarke, M.D.
  6. David J. Daniels, M.D., Ph.D.
  7. Giuseppe Lanzino, M.D.
  8. Michael J. Link, M.D.
  9. W. Richard Marsh, M.D.
  10. Fredric B. Meyer, M.D.
  11. Kai J. Miller, M.D., Ph.D.
  12. Ian F. Parney, M.D., Ph.D.
  13. Bruce E. Pollock, M.D.
  14. Jamie J. Van Gompel, M.D.


  1. John J. Chen, M.D., Ph.D.

Otolaryngology (ENT)/head and neck surgery

  1. Matthew L. Carlson, M.D.
  2. Colin (Colin) L. Driscoll, M.D.
  3. Brian A. Neff, M.D.


  1. Caterina Giannini, M.D., Ph.D.
  2. Aditya Raghunathan, M.D., M.P.H.

Pediatric hematology and oncology

  1. Jonathan D. Schwartz, D.O., M.P.H.

Pediatric neurology

  1. Gesina F. Keating, M.D.

Pediatric neurosurgery

  1. Edward S. Ahn, M.D.
  2. David J. Daniels, M.D., Ph.D.
  3. Kai J. Miller, M.D., Ph.D.

Physical medicine and rehabilitation

  1. Allen W. Brown, M.D.
  2. Robert W. DePompolo, M.D.


  1. Tanya M. Brown, Ph.D., L.P.
  2. Andrea R. Huebner, Ph.D., L.P.

Radiation oncology

  1. Paul D. Brown, M.D.
  2. Yolanda I. Garces, M.D.
  3. Nadia N. Laack, M.D.
  4. Daniel J. Ma, M.D.
  5. Anita Mahajan, M.D.
  6. Kenneth W. Merrell, M.D.
  7. Scott L. Stafford, M.D.
  8. Elizabeth Yan, M.D.


  1. Harry Cloft, M.D., Ph.D.
  2. Bradley J. Erickson, M.D., Ph.D.
  3. David F. Kallmes, M.D.
  4. Timothy J. Kaufmann, M.D., M.S.
  5. Kelly K. Koeller, M.D.
  6. Michelle A. Neben Wittich, M.D.
  7. Douglas A. Nichols, M.D.
  8. Theodore J. Passe, M.D.
  9. John D. Port, M.D., Ph.D.

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

Specialists in the Brain Tumor Program are organized into disease-oriented teams to enhance collaboration, research and patient care.

Each year more than 6,000 adults and children with brain tumors and other central nervous system cancers find the help they need at Mayo Clinic. For many people, surgery is the best option. Clinic neurosurgeons perform more than 3,000 brain and central nervous system surgeries yearly. This type of expertise is vital to planning and conducting brain surgery. And this high level of expertise means our surgeons are capable of removing brain tumors that otherwise might be considered inoperable.

Mayo Clinic neurosurgeons specialize in minimally invasive techniques, which often result in reduced hospital stays, shorter recovery times and a lower expected mortality rate in brain tumor surgery. The clinic's adult 30-day mortality rate for brain tumor surgery is only 0.3%, compared with 1% to 4% nationally. At Mayo Clinic, many people leave the hospital one or two days after surgery.

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Jacksonville, Florida, and Mayo Clinic in Phoenix/Scottsdale, Arizona., rank among the Best Hospitals for neurology and neurosurgery and for cancer in the U.S. News & World Report rankings. Mayo Clinic Children's Center in Rochester is ranked the No. 1 hospital in Minnesota, and the five-state region of Iowa, Minnesota, North Dakota, South Dakota and Wisconsin, according to U.S. News & World Report's 2023–2024 "Best Children's Hospitals" rankings. With the emphasis on collaborative care, specialists interact very closely with their colleagues across all sites.

Learn more about Mayo Clinic's quality rankings.

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Mayo Clinic clinician-researchers and scientists investigate better ways to diagnose and treat all types of brain tumors. One focus is translational research, in which findings from the lab and clinical trials are applied to address unmet patient needs in the clinic. For example, a scientist in mathematical oncology is learning how to predict where brain tumors might be at a microscopic level. This may help doctors decide where precisely to operate, even if tumors don't show up on a scan.

Other leading-edge studies include:

  • Developing new brain mapping techniques for hard-to-treat tumors
  • Improving diagnostics and the ability to tailor treatment to each person by studying genetic alterations in brain tumor cells
  • Harnessing the immune system to kill tumor cells using vaccines
  • Exploring the use of nanotechnologies to treat brain tumors
  • Targeting brain cancer cells with viruses
  • Understanding how brain cancer cells invade surrounding brain tissues

If you receive care in the Mayo Clinic Brain Tumor Program, your doctor may invite you to take part in one of the clinical trials testing new treatments. Mayo Clinic is part of the Alliance for Clinical Trials in Oncology, a clinical trials network sponsored by the National Cancer Institute that gives Mayo patients access to experimental treatments being studied around the country.

Mayo Clinic has an extensive effort in brain tumor research, spanning numerous centers, programs and labs across all campuses in Arizona, Florida and Minnesota.

Research labs

Explore research labs.

Related research laboratories and programs:

Our patients tell us that the quality of their interactions, our attention to detail and the efficiency of their visits mean health care like they've never experienced. See the stories of satisfied Mayo Clinic patients.

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals, or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.