DepartmentsNeurologySpecialty GroupsBrain Tumor ProgramLocationRochester, MinnesotaLanguagesEnglishExisting patientsSend a secure message via patient portal Appointments 507-923-2627 Request an appointment online Biographical summaryDr. Ruff specializes in the treatment of cancers arising from the nervous system, as well as the neurologic complications of systemic cancers and their treatment. His primary research interest is clinical trial development and cell based therapies (CAR-T therapy) for CNS malignancies. Conditions treatedBrain tumorGlioblastomaGliomaMeningiomaSpinal cord tumor Procedures performedChemotherapyLumbar puncture InterestsGlioma and the complications of its treatment.Neurocutaneous syndromes.Experimental therapeutics in neuro-oncology.CAR-T associated complications.CAR-T development for malignant glioma. Mayo Clinic locations Rochester, Minnesota Driving directions More info Billing & insurance Accessibility services Education2018FellowRST Neuro-Oncology, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine2017ResidentNeurology, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine2017InternshipMayo Graduate School of Medical Education2013MDUniversity of Missouri School of Medicine2009BS - BiologyMissouri State UniversityShow more education Activities and honorsCertifications2022Brain Injury MedicineAmerican Board of Psychiatry and Neurology2017NeurologyAmerican Board of Psychiatry and NeurologyAwards and honors2013Dean's Research AwardUniversity of Missouri School of Medicine2012Medical Student Prize for Excellence in NeurologyAmerican Academy of Neurology2009Horace E. Thomas and Helen Y. Thomas Medical Student ScholarshipUniversity of Missouri School of Medicine2009Phi Kappa Phi Honor Society2008Sechler Family Scholarship RecipientMissouri State University2008M&B Ingram Endowed Scholarship recipientMissouri State University2007Grant recipientMissouri Access Program2007SMART Grant recipientUnited States Department of EducationShow more awards and honorsProfessional memberships2018 - presentMemberEuropean Association for Neuro-Oncology2017MemberResident Nurse Counsel, Department of Neurology2017 - presentMemberAmerican Academy of Neurology2016 - 2017MemberMayo Neurology Resident Curriculum Committee, Department of Neurology2016 - presentMemberSociety for Neuro-Oncology2016 - presentMemberAmerican Society of Clinical Oncology2015 - 2017MemberResidency Recruitment Committee, Department of NeurologyShow more professional membershipsPublicationsSee my publications Biographical summaryConditions treatedProcedures performedInterestsMayo Clinic locationsEducationActivities and honors Request an appointment PST-20437877 Doctors & Medical Staff Ruff, Michael W. M.D.