Most people can get a COVID-19 vaccine if they have an existing health condition, so long as they haven’t had an allergic reaction to a COVID-19 vaccine or to any of its ingredients. But there is limited information available about the safety of COVID-19 vaccines in people who have weakened immune systems or autoimmune conditions. In addition, a COVID-19 vaccine might not fully protect people from COVID-19 who have a weakened immune system that is caused by HIV, certain conditions or medications. They may need to continue taking precautions.

If you have questions about the vaccine and you have any existing health conditions — including a weakened immune system or autoimmune conditions — or you take medications, talk to your doctor.