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Amy C. Degnim, M.D.

  1. Surgical Oncologist

Dr. Amy Degnim has been a member of the Mayo Clinic staff since 2003. Currently, she serves as consultant in the Department of Surgery and is the Joe M. and Ruth Roberts Professor of Surgery, Mayo Clinic College of Medicine. Dr. Degnim's clinical practice consists of benign and malignant breast disease. She led development of a nationally recognized breast surgery program at Mayo Clinic with national and international presence. She developed the Multidisciplinary Breast Fellowship at Mayo Clinic and served as the initial Program Director.

Dr. Degnim's clinical interests are related to breast cancer surgery and other rare tumor types such as angiosarcoma, as well as high risk breast lesions. Dr. Degnim also leads many research projects related to predicting individual breast cancer risk, and using novel approaches to prevent breast cancer, including topical agents and vaccines. She leads the Mayo Clinic Benign Breast Disease Cohort, a multidisciplinary research study involving approximately 15,000 women, including the study of histology, immunology, genomics, and mammographic changes that are associated with risk of developing breast cancer.

  1. Atypical ductal hyperplasia
  2. Atypical hyperplasia of the breast
  3. Atypical lobular hyperplasia
  4. BRCA gene mutation
  5. Breast cancer
  6. Breast cysts and lumps
  7. Ductal carcinoma in situ
  8. Fibroadenoma
  9. HER2-positive breast cancer
  10. Inflammatory breast cancer
  11. Invasive ductal carcinoma
  12. Invasive lobular carcinoma
  13. Lobular carcinoma in situ
  14. Luminal A breast cancer
  15. Luminal B breast cancer
  16. Male breast cancer
  17. Medullary breast cancer
  18. Mucinous breast cancer
  19. Paget's disease of the breast
  20. Paget's disease of the nipple
  21. Papillary breast cancer
  22. Phyllodes tumor
  23. Recurrent breast cancer
  24. Squamous cell carcinoma of the breast
  25. Stage 4 breast cancer
  26. Triple-negative breast cancer
  27. Triple-positive breast cancer
  28. Tubular breast cancer
  1. Breast abscess drainage
  2. Breast biopsy
  3. Breast cancer surgery
  4. Breast duct excision
  5. Breast surgery
  6. Double mastectomy
  7. Excisional biopsy
  8. Lumpectomy
  9. Lymph node sampling
  10. Lymphadenectomy
  11. Mastectomy
  12. Minimally invasive surgery
  13. Modified radical mastectomy
  14. Nipple-sparing mastectomy
  15. Oncoplastic breast-conserving surgery
  16. Prophylactic mastectomy
  17. Radioactive seed localization
  18. Sentinel lymph node surgery
  19. Sentinel node biopsy
  20. Skin-sparing mastectomy
  21. Wire localization for breast surgery
  • Breast cancer risk prevention
  • Surgical complications of breast and axillary surgery
  • Prediction of breast cancer metastasis in nonsentinel nodes of patients with a positive sentinel node
  1. 2011
    Certificate - Certificate in Translational ResearchMayo Graduate School of Medicine, Mayo Clinic College of Medicine
  2. 2003
    Fellow - Breast SurgeryDepartment of Surgery, University of Michigan
  3. 1998
    ResidentDepartment of Surgery, University of North Carolina
  4. 1991
    MDUniversity of North Carolina School of Medicine
  5. 1987
    Research Fellowship - PathologyUniversity of Virginia
  6. 1987
    BS - ChemistryUniversity of Notre Dame

Certifications

  1. 1999
    General SurgeryAmerican Board of Surgery

Awards and honors

  1. 2018
    Joe M. & Ruth Roberts Professor of SurgeryMayo Foundation
  2. 2009
    K12 Career Development AwardNational Institutes of Health
  3. 2003
    Excellence in Teaching RecognitionMayo Medical School, Mayo Clinic College of Medicine and Science, Department of Education Administration
  4. 1990
    Alpha Omega Alpha Honor Society, Elected Junior YearUniversity of North Carolina
  5. 1989
    Merit AwardUniversity of North Carolina
  6. 1989
    AwardLange Medical Publications
  7. 1987
    MemberPhi Beta Kappa Honor Society
  8. 1987
    MemberAlpha Epsilon Delta National Premedical Honor Society, Southeast Region
  9. 1987
    Merit AwardUniversity of North Carolina
  10. 1983
    Notre Dame Scholar every year (top 15% of class)Awarding Organization
  11. 1983
    Dean's List, every semesterUniversity of Notre Dame

Professional memberships

  1. 2024 - present
    Co-LeaderMayo Clinic Comprehensive Cancer Center, Advanced Clinical and Translational Science (ACTS)
  2. 2020 - present
    Co-LeaderPrevention Committee, Alliance for Clinical Trials in Oncology
  3. 2018 - present
    MemberMayo Clinic Cancer Center Ad Hoc Committee for Education
  4. 2017 - present
    MemberWomen's Health Executive Subcommittee, Clinical Practice Committee - Rochester
  5. 2015 - present
    Thesis AdvisorThesis Advisory Committee, Curriculum Subcommittee, Clinical Research Training Program
  6. 2014
    ReviewerNational Institute of Health
  7. 2014 - present
    Co-LeaderMayo Clnic Cancer Center - Rochester, Women's Cancer Program
  8. 2013 - 2018
    Vice ChairFellowship and Research Grant Committee, Society of Surgical Oncology
  9. 2012 - present
    Full MemberMayo Clinic Cancer Center, Women's Cancer Program, Cancer Prevention & Control Program
  10. 2012 - present
    MemberMayo Clinic Cancer Center, Women's Cancer Program
  11. 2012 - present
    Faculty AdvisorMayo Clinic Center for Translational Science Activities
  12. 2012 - 2024
    LeaderBenign Breast Disease Cohort
  13. 2012 - 2018
    LeadCancer Prevention Network
  14. 2012 - 2018
    Committee MemberPatient Safety Quality Committee, American Society of Breast Surgeons
  15. 2012 - present
    MentorResearch Committee, Department of Surgery
  16. 2011 - present
    MemberSurgery Research Executive Committee, Department of Surgery
  17. 2011 - 2018
    ChairSurgical Peer Review Research Committee, Department of Surgery
  18. 2011
    Expert ReviewerAgency for HealthCare Research and Quality, U.S. Department of Health and Human Services
  19. 2011
    ConsultantAgency for HealthCare Research and Quality, U.S. Department of Health and Human Services
  20. 2011 - present
    Co-authorBreast Education Self-Assessment Program (BESAP), American Society of Breast Surgeons
  21. 2011 - present
    MemberAmerican Association for Cancer Research
  22. 2011 - present
    Committee MemberPrevention Committee, Alliance for Clinical Trials in Oncology
  23. 2009
    MemberGeneral Surgery Journal Club, Mayo Clinic Rochester Surgical Committee, Mayo Clinic Rochester Committees
  24. 2008 - 2014
    Community Editor, Web PortalAmerican College of Surgeons
  25. 2008 - 2011
    MemberASBD Consensus Committee, American Society of Breast Disease
  26. 2008
    MemberPriorities of Laboratory Testing Committee, Mayo Clinic Rochester Committees
  27. 2008 - present
    MemberMayo Clinic Center for Translational Science Activities
  28. 2007 - 2012
    MemberInternational Society of Surgery
  29. 2007 - 2012
    MemberBreast Surgery International
  30. 2007
    MemberTask Force on Prophylactic Mastectomy Consensus Statement, Society of Surgical Oncology
  31. 2007 - present
    MemberSociety of Surgical Oncology
  32. 2006 - 2008
    HeadSearch Committee for Staff Breast Surgeon, Division of Subspecialty General Surgery, Department of Surgery
  33. 2006 - 2008
    MemberSearch Committee for Staff Breast Surgeon, Division of Subspecialty General Surgery, Department of Surgery
  34. 2006 - 2008
    Division RepresentativeGonda 15 Outpatient Surgery Center (Division Representative), Division of Subspecialty General Surgery, Department of Surgery
  35. 2006 - 2008
    HeadWorking Group to develop National web-based case log for breast fellowship training programs, Society of Surgical Oncology
  36. 2006 - 2007
    Grant ReviewerMayo Clinic Cancer Center
  37. 2006 - present
    ModeratorBreast Journal Club, Department of Surgery
  38. 2006 - present
    ModeratorGeneral Surgery Journal Club, Mayo Clinic Rochester Surgical Committee, Mayo Clinic Rochester Committees
  39. 2006 - present
    MemberBreast SPORE Research Core Group
  40. 2006 - present
    MemberMayo Clinic Cancer Center
  41. 2006 - present
    MemberBreast Spore Operations Committee
  42. 2005 - 2008
    MemberMedical Record Review Subcommittee, Accreditation Committee, Mayo Clinic Rochester Committees
  43. 2005 - 2010
    Fellowship Program DirectorMayo Foundation for Medical Education and Research
  44. 2005 - 2006
    MemberPharmacy and Therapeutics Subcommittee - Rochester, Clinical Practice Committee - Rochester
  45. 2004 - 2011
    MemberSurgical Research Committee, Mayo Clinic Rochester Committees
  46. 2004 - 2006
    Physician LiaisonPatient Education, Division of Subspecialty General Surgery, Department of Surgery
  47. 2004 - 2006
    MemberPatient Education, Division of Subspecialty General Surgery, Department of Surgery
  48. 2004 - 2006
    MemberASBD Consensus Clearinghouse, Diagnosis Working Group
  49. 2004 - present
    MemberMinnesota Surgical Society
  50. 2003 - 2011
    MemberAmerican College of Surgeons Oncology Group
  51. 2003 - 2011
    MemberNorth Central Cancer Treatment Group, National Cancer Institute, National Institutes of Health
  52. 2003 - 2005
    MemberWomen's Healthcare Council, Mayo Clinic Rochester Committees
  53. 2003 - present
    MemberMultidisciplinary Breast Conference
  54. 2003 - present
    MemberNorth Central Cancer Treatment Group
  55. 2003 - present
    MemberPriestley Society
  56. 2002 - 2011
    MemberAmerican Society of Breast Disease
  57. 2001 - present
    FellowAmerican College of Surgeons
  58. 2001 - present
    MemberAmerican Society of Breast Surgeons
  59. 2000 - present
    MemberAmerican Society of Clinical Oncology
  60. 1999 - present
    MemberAmerican Board of Surgery
  61. 1998 - 2002
    MemberMassachusetts Medical Society
  62. 1998 - present
    MemberNathan A. Womack Surgical Society

Publications

Research activities

See a description of research activities.