Mayo Clinic's approach

Teamwork

In Mayo Clinic's Department of Clinical Genomics, medical geneticists and certified genetic counselors work together as a team, bringing in other professionals as needed. The team evaluates any type of genetic condition and coordinates many types of tests and procedures.

Comprehensive services

The Department of Clinical Genomics offers diagnostic workup of rare conditions and conditions passed down in families. It also offers genetic evaluation of hereditary cancer syndromes and other genetic conditions. The team does a comprehensive family history and educates patients and families about familial conditions. The team also offers counseling for family members to improve understanding of how a genetic condition may affect them.

Advanced technology

Mayo Clinic's Department of Clinical Genomics provides access to the latest genomic testing techniques, when medically needed and on a case-by-case basis.

New gene panels

Mayo Clinic's Department of Laboratory Medicine and Pathology offers new and updated comprehensive genetic panels. A genetic panel is a type of genetic test that looks at more than one gene at the same time to find gene changes. Examples include:

  • Pancreatitis gene panel. This test looks at genes of people who have long-term pancreas conditions or who might have a family history of them. This helps healthcare professionals better understand the risks and how the conditions might progress.
  • Idiopathic pulmonary fibrosis gene panel. This test is for people who have a personal or family history of a lung disease called idiopathic pulmonary fibrosis, also called IPF. The test checks more than 25 genes linked to IPF that can be passed down in families. This helps healthcare professionals find the condition early and plan the best way to treat it.
  • Inflammatory bowel disease gene panel. This test looks at more than 100 genes linked to a type of inflammatory bowel disease, also called IBD, that starts early in life. The condition is caused by a single gene change that's passed down in families. The test helps healthcare professionals diagnose and treat people who might have this type of IBD.

Research

Mayo Clinic's Department of Clinical Genomics is recognized for outstanding contributions to research. It has a long history of published studies on rare or novel genetic conditions.

Expertise and rankings

  • First in the U.S. to offer a lymphoma genomic diagnostic test for patients. Mayo Clinic created a test to help guide diagnosis and treatment of patients with diffuse large B-cell lymphoma, the most common type of non-Hodgkin lymphoma.
  • Nationally recognized expertise. Mayo Clinic's Department of Clinical Genomics includes experienced board-certified medical geneticists, certified genetic counselors and other healthcare professionals. Using a comprehensive team approach, they work with all age groups and levels of complexity, tailoring care to each person's needs.
  • Familial Cancer Program. This comprehensive program is designed to help identify people at higher risk of cancer due to hereditary factors. Education and counseling about cancer risk, lowering cancer risk, effective screening and prevention options are key aspects of the program. Genetic testing is available when appropriate. A multispecialty team provides monitoring and treatment as needed.
  • Cardiovascular Genomics Program. This comprehensive program offers cardiovascular evaluation, genetic counseling, genetic testing and screening for family members of people living with or at risk of inherited heart and blood vessel conditions.

Mayo Clinic Children's

Highly skilled pediatric experts diagnose and treat all types of conditions in children. As a team, we work together to find answers, set goals and develop a treatment plan tailored to your child's needs.

Learn more about Mayo Clinic Children's.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

Clinical trials

Explore Mayo Clinic studies of tests and procedures to help prevent, detect, treat or manage conditions.

Feb. 27, 2026
  1. Genetic testing for cancer risk. American Cancer Society. https://www.cancer.org/cancer/risk-prevention/genetics/genetic-testing-for-cancer-risk.html. Accessed Aug. 25, 2025.
  2. Genetic testing. Centers for Disease Control and Prevention. https://www.cdc.gov/genomics-and-health/counseling-testing/genetic-testing.html. Accessed Aug. 25, 2025.
  3. Genetic testing. American Medical Association. https://www.ama-assn.org/delivering-care/population-health/genetic-testing. Accessed Aug. 25, 2025.
  4. Direct-to-consumer genetic testing. American Medical Association. https://www.ama-assn.org/delivering-care/population-health/direct-consumer-genetic-testing. Accessed Aug. 25, 2025.
  5. Genetic discrimination. American Medical Association. https://www.ama-assn.org/delivering-care/population-health/genetic-discrimination. Accessed Aug. 25, 2025.
  6. FAQs: Prenatal genetic screening tests. American College of Obstetricians and Gynecologists. https://www.acog.org/womens-health/faqs/prenatal-genetic-screening-tests. Accessed Aug. 25, 2025.
  7. American College of Obstetricians and Gynecologists. Practice Bulletin No. 162: Prenatal diagnostic testing for genetic disorders. Obstetrics & Gynecology. 2016; doi:10.1097/AOG.0000000000001438. Reaffirmed 2024.
  8. Hertz DL, et al. Recommendations for pharmacogenetic testing in clinical practice guidelines in the US. American Journal of Health-System Pharmacy. 2024; doi:10.1093/ajhp/zxae110.
  9. FAQs: BRCA1 and BRCA2 mutations. American College of Obstetricians and Gynecologists. https://www.acog.org/womens-health/faqs/brca1-and-brca2-mutations. Accessed Aug. 25, 2025.
  10. FAQs: Carrier screening. American College of Obstetricians and Gynecologists. https://www.acog.org/womens-health/faqs/carrier-screening. Accessed Aug. 25, 2025.
  11. Genetic testing for inherited cancer risk. National Cancer Institute. https://www.cancer.gov/about-cancer/causes-prevention/genetics/genetic-testing-fact-sheet. Accessed Aug. 25, 2025.
  12. Idiopathic pulmonary fibrosis gene panel, varies. Mayo Clinic Laboratories. https://www.mayocliniclabs.com/test-catalog/overview/621589#Clinical-and-Interpretive. Accessed Aug. 25, 2025.
  13. Expanded pancreatitis gene panel, varies. Mayo Clinic Laboratories. https://www.mayocliniclabs.com/test-catalog/overview/621965#Clinical-and-Interpretive. Accessed Aug. 25, 2025.
  14. Early onset monogenic inflammatory bowel disease (IBD) gene panel, varies. Mayo Clinic Laboratories. https://www.mayocliniclabs.com/test-catalog/overview/620120#Clinical-and-Interpretive. Accessed Aug. 25, 2025.
  15. Huntington's disease. National Institute of Neurological Disorders and Stroke. https://www.ninds.nih.gov/health-information/disorders/huntingtons-disease. Accessed Aug. 27, 2025.
  16. Kim H, et al. Clinical circulating tumor DNA testing for precision oncology. Cancer Research and Treatment. 2023; doi:10.4143/crt.2022.1026.
  17. Newborn screening: Condition information. Health Resources & Services Administration. https://newbornscreening.hrsa.gov/conditions. Accessed Aug. 28, 2025.
  18. Newborn screening process. Health Resources & Services Administration. https://newbornscreening.hrsa.gov/newborn-screening-process. Accessed Aug. 28, 2025.
  19. Medical review (expert opinion). Mayo Clinic. Sept. 12, 2025.

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