Cardiovascular Medicine

People living with or at risk of inherited heart and blood vessel disorders are helped at the Cardiovascular Genomics Program. It offers comprehensive cardiovascular evaluation and genetic counseling and testing.

Videos

Watch Mayo Clinic cardiologists and others discuss many conditions and treatments related to cardiovascular diseases and cardiovascular surgery.

Mayo Clinic was among the first medical centers to offer comprehensive evaluation and management of people with inherited heart conditions. These conditions include:

• Marfan syndrome.
• Long QT syndrome.
• Hypertrophic cardiomyopathy.
• Familial hypercholesterolemia.

Your treatment team may include a doctor who specializes in heart disease and genetics (genomic cardiologist), a preventive cardiologist, a genetic counselor, nurse practitioners and registered nurses trained in helping you reduce your risk of heart disease. This team works with other specialty areas as needed to help ensure you get exactly the care you need. If you wish, your care team will talk with your primary care provider about your treatment plan.

Treatment for adults is offered at the Cardiovascular Genomics Program at Mayo Clinic in Arizona, Florida and Minnesota. Services for children, including infants, are available at Mayo Clinic in Rochester, Minnesota. Staff includes specialists trained in treating children with heart conditions (pediatric cardiologists).

Services

If you have a family history of heart conditions, talk with your doctor about the availability of genetic counseling and testing. Clinical and genetic screenings, interpretation of test results and treatment can help you and your loved ones live longer, healthier lives. A Mayo Clinic cardiologist will work with you and the experts of the Cardiovascular Genomics Program to develop a personalized treatment approach.

The Cardiovascular Genomics Program offers several services, including:

• Marfan Syndrome and Thoracic Aorta Clinic.
• Long QT Syndrome and Genetic Heart Disorders Clinic.
• Hypertrophic Cardiomyopathy Clinic.
• Familial Hypercholesterolemia Clinic.

Tests and procedures used to help diagnose and treat these conditions in these clinics include:

• Personal and family history.
• Genetic testing and counseling.
• Individualized screening and treatment options.
• Screening of family members.
• Education and support for you and your family.
• Specialty evaluation.

Not all procedures may be available at all locations. Please confirm when you request an appointment.

Comprehensive Care for Genetic Cardiovascular Disorders

The experts of the Cardiovascular Genomics Program specialize in treating the following conditions.

• Marfan syndrome, Loeys-Dietz syndrome, vascular Ehlers-Danlos syndrome, and other connective tissue disorders, bicuspid aortopathy, familial thoracic aortic aneurysm and dissection (FTAAD) syndromes.
• Long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia (CPVT), and other sudden cardiac arrest syndromes.
• Hypertrophic cardiomyopathy, Fabry disease, LV noncompaction, arrhythmogenic right ventricular cardiomyopathy (ARVC).
• Familial hypercholesterolemia and other heritable disorders of lipid metabolism.
• Dilated cardiomyopathy, familial forms of amyloidosis.

Innovative research

Doctors in the Cardiovascular Genomics Program conduct research in many areas, including heart disease prevention and genetic testing to evaluate heart disease risk and who might benefit from early and aggressive intervention.

Other areas of study are:

• Marfan syndrome and other aortopathies.
• Long QT/sudden cardiac death.
• Hypertrophic cardiomyopathy, Fabry disease, left ventricular noncompaction.
• Familial hypercholesterolemia and other heritable disorders of lipid metabolism.
• Dilated cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy (ARVC).

Learn more about research in the Cardiovascular Research Center and the Center for Individualized Medicine.

Nationally recognized expertise

Mayo Clinic is top-ranked in more specialties than any other hospital and has been recognized as an Honor Roll member according to the U.S. News & World Report's 2024-2025 "Best Hospitals" rankings.

Mayo Clinic campuses are nationally recognized for expertise in cardiology and cardiovascular surgery:

• Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Phoenix/Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, are ranked among the Best Hospitals for heart and heart surgery by U.S. News & World Report.
• Mayo Clinic Children's in Rochester is ranked the No. 1 hospital in Minnesota, and the five-state region of Iowa, Minnesota, North Dakota, South Dakota and Wisconsin, according to U.S. News & World Report's 2024–2025 "Best Children's Hospitals" rankings.