Departments and specialties

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

Doctors who perform this procedure

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Displaying 1-10 out of 18 doctors available

  1. Edward S. Ahn, M.D.

    Edward S. Ahn, M.D.

    1. Pediatric Neurosurgeon
    1. Rochester, MN
    Areas of focus:

    Endoscopic procedure, Craniotomy, Fetal surgery, Pediatric cervical spine surgery, Brain shunt placement, Brain biopsy,... Spina bifida, Hydrocephalus, Moyamoya disease, Craniosynostosis, Myelopathy, Chiari malformation, Arteriovenous malformation

  2. Bernard R. Bendok, M.D.

    Bernard R. Bendok, M.D.

    1. Neurosurgeon
    1. Phoenix, AZ
    Areas of focus:

    Carotid angioplasty and stenting, Craniotomy, Minimally invasive surgery, Endarterectomy, Stereotactic radiosurgery, Br...ain tumor surgery, Microvascular surgery, Brain shunt placement, Brain biopsy, Meningioma, Acoustic neuroma, Pituitary tumor, Chordoma, Moyamoya disease, Brain tumor, CSF leak, Brain aneurysm, Brain metastasis, Glioblastoma, Astrocytoma, Oligodendroglioma, Neurofibromatosis, Glioma, Ependymoma, Vascular malformation, Arteriovenous malformation, Spinal cord tumor, Nerve sheath tumor, Central nervous system vascular malformations, Cavernous hemangioma, Neurofibroma, Plexiform neurofibroma, Pineal gland tumor, Ganglioglioma, Choroid plexus papilloma

  3. Terry C. Burns, M.D., Ph.D.
    Areas of focus:

    Brain stereotactic radiosurgery, Craniotomy, Awake brain surgery, Brain tumor surgery, Intraoperative magnetic resonanc...e imaging, Brain biopsy, Gamma knife surgery, Meningioma, Brain tumor, Brain metastasis, Diffuse glioma, Glioblastoma, Astrocytoma, Oligodendroglioma, Ependymoma, Medulloblastoma, Pilocytic astrocytoma, Diffuse midline glioma

  4. Rich W. Byrne, M.D.

    Rich W. Byrne, M.D.

    1. Neurosurgeon
    1. Jacksonville, FL
    Areas of focus:

    Endoscopic procedure, Transsphenoidal surgery, Craniotomy, Minimally invasive surgery, Brain tumor surgery, Skull base ...surgery, Minimally invasive neurosurgery, Peripheral nerve tumor surgery, Keyhole craniotomy, Brain biopsy, Epilepsy, Meningioma, Acoustic neuroma, Pituitary tumor, Craniopharyngioma, Chordoma, Brain cancer, Brain tumor, CSF leak, Brain metastasis, Glioblastoma, Astrocytoma, Oligodendroglioma, Oligoastrocytoma, Glioma, Peripheral nerve tumor, Neuroblastoma, Chondrosarcoma, Skull base tumor, Esthesioneuroblastoma, Brainstem tumor, Brain tumor-associated epilepsy, Glioma-associated epilepsy

  5. Kaisorn L. Chaichana, M.D.

    Kaisorn L. Chaichana, M.D.

    1. Neurosurgeon
    1. Jacksonville, FL
    Areas of focus:

    Radiation therapy, Endoscopic procedure, Transsphenoidal surgery, Brain stereotactic radiosurgery, Craniotomy, Awake br...ain surgery, Minimally invasive surgery, Pituitary tumor surgery, Laser ablation, Stereotactic radiosurgery, Brain tumor surgery, Skull base surgery, Minimally invasive neurosurgery, Peripheral nerve tumor surgery, Laser interstitial thermal therapy, Keyhole craniotomy, External ventricular drain placement, Brain biopsy, Endoscopic skull base surgery, Gamma knife surgery, Meningioma, Acoustic neuroma, Pituitary tumor, Craniopharyngioma, Chordoma, Brain cancer, Brain tumor, CSF leak, Brain metastasis, Glioblastoma, Astrocytoma, Oligodendroglioma, Oligoastrocytoma, Glioma, Ependymoma, Spinal cord tumor, Peripheral nerve tumor, Neuroblastoma, Chondrosarcoma, Schwannoma, Skull base tumor, Esthesioneuroblastoma, Optic glioma, Brainstem tumor, Pineal gland tumor, Brain tumor-associated epilepsy, Glioma-associated epilepsy

  6. Victoria E. Clark, M.D., Ph.D.

    Victoria E. Clark, M.D., Ph.D.

    1. Neurosurgeon
    1. Jacksonville, FL
    Areas of focus:

    Radiation therapy, Brain stereotactic radiosurgery, Craniotomy, Awake brain surgery, Stereotactic radiosurgery, Brain t...umor surgery, Skull base surgery, Minimally invasive neurosurgery, Laser interstitial thermal therapy, Brain biopsy, Gamma knife surgery, Meningioma, Acoustic neuroma, Brain cancer, Brain tumor, Brain metastasis, Glioblastoma, Astrocytoma, Oligodendroglioma, Oligoastrocytoma, Glioma, Ependymoma, Spinal cord tumor, Schwannoma, Skull base tumor, Brain tumor-associated epilepsy, Glioma-associated epilepsy

  7. David J. Daniels, M.D., Ph.D.
    Areas of focus:

    Craniotomy, Brain tumor surgery, Pediatric cervical spine surgery, Pediatric neurosurgery, External ventricular drain p...lacement, Brain biopsy, Brain tumor, Diffuse glioma, Pediatric brain tumor, Glioma, Embryonal tumor, Diffuse midline glioma, Atypical teratoid rhabdoid tumor

  8. Michael J. Link, M.D.

    Michael J. Link, M.D.

    1. Neurosurgeon
    1. Rochester, MN
    Areas of focus:

    Brain stereotactic radiosurgery, Craniotomy, Acoustic neuroma surgery, Brain tumor surgery, Hemifacial spasm surgery, T...rigeminal neuralgia surgery, Brain biopsy, Trigeminal neuralgia, Acoustic neuroma, Brain tumor, Astrocytoma, Nerve sheath tumor, Hemifacial spasm, Cerebrovascular disease

  9. W. Richard Marsh, M.D.

    W. Richard Marsh, M.D.

    1. Neurosurgeon
    1. Rochester, MN
    Areas of focus:

    Epilepsy surgery, Craniotomy, Brain tumor surgery, Intraoperative magnetic resonance imaging, Hemifacial spasm surgery,... Chiari malformation surgery, Trigeminal neuralgia surgery, Brain biopsy, Epilepsy, Trigeminal neuralgia, Brain tumor, Degenerative disk disease, Chiari malformation, Spinal cord tumor, Syringomyelia, Hemifacial spasm

  10. Fredric B. Meyer, M.D.

    Fredric B. Meyer, M.D.

    1. Neurosurgeon
    1. Rochester, MN
    Areas of focus:

    Epilepsy surgery, Craniotomy, Awake brain surgery, Pituitary tumor surgery, Brain tumor surgery, Hemifacial spasm surge...ry, Trigeminal neuralgia surgery, Brain biopsy, Epilepsy, Trigeminal neuralgia, Hydrocephalus, Moyamoya disease, Brain tumor, Brain aneurysm, Astrocytoma, Oligodendroglioma, Spinal cord tumor, Embryonal tumor, Hemifacial spasm, Brainstem tumor, Pineal gland tumor

Research

Doctors and surgeons trained in nervous system conditions are called neurologists and neurosurgeons. They are working to improve care for people who need a craniotomy. Researchers for the Brain Tumor Program study better ways to diagnose and treat all brain tumors. One area of study includes developing brain-mapping techniques for hard-to-reach tumors.

Some other areas studied by Mayo Clinic researchers include:

  • The potential advantages of different types of craniotomies, including pterional keyhole craniotomy and supraorbital keyhole craniotomy.
  • Techniques used in awake brain mapping for better outcomes after a craniotomy.
  • The safety and potential risks of a craniotomy, along with the risk of delaying the procedure.

Publications

See a list of publications about craniotomy by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

Oct. 02, 2025
  1. Craniotomy. National Cancer Institute. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/craniotomy. Accessed July 30, 2025.
  2. Treatments and side effects. American Brain Tumor Association. https://www.abta.org/about-brain-tumors/treatments-side-effects/. Accessed July 30, 2025.
  3. Surgery for adult brain and spinal cord tumors. American Cancer Society. https://www.cancer.org/cancer/types/brain-spinal-cord-tumors-adults/treating/surgery.html. Accessed July 30, 2025.
  4. Living as a brain or spinal cord tumor survivor. American Cancer Society. https://www.cancer.org/cancer/types/brain-spinal-cord-tumors-adults/after-treatment/follow-up.html. Accessed July 30, 2025.
  5. Vogelbaum MA, et al. Treatment for brain metastases: ASCO-SNO-ASTRO guideline. Journal of Clinical Oncology. 2022; doi:10.1200/JCO.21.02314.
  6. Brain cancer: Glioma. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=patients&id=5. Accessed July 30, 2025.
  7. Rao D, et al. An illustrative review of common modern craniotomies. Journal of Clinical Imaging Sciences. 2020; doi:10.25259/JCIS_176_2020.
  8. Ong V, et al. The pterional keyhole craniotomy approach: A historical perspective. World Neurosurgery. 2023; doi:10.1016/j.wneu.2023.07.012.
  9. Florez-Perdomo WA, et al. Supraorbital vs pterional keyhole for anterior circulation aneurysms: A systematic review and meta-analysis. World Neurosurgery: X. 2023; doi:10.1016/j.wnsx.2023.100177.
  10. Karadimas S, et al. Minimally invasive and outpatient aneurysm surgery: New concepts. Neurosurgery Clinics of North America. 2022; doi:10.1016/j.nec.2022.05.005.
  11. Robinow ZM, et al. Supraorbital keyhole craniotomy via eyebrow incision: A systematic review and meta-analysis. World Neurosurgery. 2022; doi:10.1016/j.wneu.2021.11.015.
  12. Xie T, et al. Endoscopic far-lateral supracerebellar infratentorial approach for petroclival region meningioma: Surgical technique and clinical experience. Operative Neurosurgery. 2022; doi:10.1227/ons.0000000000000126.
  13. Winn HR, ed. Awake craniotomy and intraoperative mapping. In: Youmans and Winn Neurological Surgery. 8th ed. Elsevier; 2023. https://www.clinicalkey.com. Accessed July 30, 2025.
  14. Quinones-Hinojosa A, ed. Surgical management of intracerebral hemorrhage. In: Schmidek & Sweet: Operative Neurosurgical Techniques. 7th ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed Aug. 12, 2025.
  15. Strowd RE. Approach to a patient with brain metastasis. In: Neuro-Oncology for the Clinical Neurologist. Elsevier; 2021. https://www.clinicalkey.com. Accessed Aug. 12, 2025.
  16. Jandial R. Pterional (frontosphenotemporal) craniotomy. In: Core Techniques in Operative Neurosurgery. 2nd ed. Elsevier; 2020. https://www.clinicalkey.com. Accessed Aug. 12, 2025.
  17. Functional MRI (fMRI). RadiologyInfo.org. https://www.radiologyinfo.org/en/info/fmribrain. Accessed Aug. 12, 2025.
  18. Bertani R, et al. Minimally invasive craniotomies for lesions of the anterior and middle fossa. Neurosurgical Review. 2022; doi:10.1007/s10143-022-01850-z.
  19. Kulikov A, et al. Preoperative risk assessment before elective craniotomy: Are aspirin, arrhythmias, deep venous thromboses and hyperglycemia contraindications to surgery? World Neurosurgery. 2024; doi:10.1016/j.wneu.2024.03.018.
  20. Ekert JO, et al. Awake brain mapping paradigms for nondominant hemisphere gliomas. Neurosurgical Focus. 2024; doi:10.3171/2023.11.FOCUS23610.
  21. Perez-Vega C, et al. Safety and feasibility of a fast-track pathway for neurosurgical craniotomy patients: Bypassing the intensive care unit. Mayo Clinic Proceedings. 2023; doi:10.1016/j.mayocpiqo.2023.09.002.
  22. Marenco-Hillembrand L, et al. Unilateral supraorbital keyhole craniotomy avoiding the frontal sinus for large and giant olfactory-groove meningiomas: A case series. World Neurosurgery. 2023; doi:10.1016/j.wneu.2022.11.015.
  23. Nimmagadda R. Allscripts EPSi. Mayo Clinic. June 4, 2024.
  24. Phoowanakulchai S, et al. Persistent incisional pain at 1 year after craniotomy: a retrospective observational study. BMC Anesthesiology. 2023; doi.org/10.1186/s12871-023-02068-2.
  25. Samagh N, et al. Post-craniotomy pain: An update. Journal of Neuroanaesthesiology and Critical Care. 2023; doi.org/10.1055/s-0042-1760271.
  26. Health Education & Content Services. Scar massage. Mayo Clinic; 2015.
  27. Gold C, et al. Bone flap management strategies for postcraniotomy surgical site infection. Surgical Neurology International. 2021; doi.org/10.25259/SNI_276_2021.
  28. Nie C, et al. Clinical outcomes of transcranial and endoscopic endonasal surgery for craniopharyngiomas: A single institution experience. Frontiers in Oncology. 2022; doi.org/10.3389/fonc.2022.755342.
  29. Ulmeanu ME, et al. Bespoke implants for cranial reconstructions: Preoperative to postoperative surgery management system. Bioengineering; 2023; doi:10.3390/bioengineering10050544.
  30. Health Education & Content Services. Subdural hematoma. Mayo Clinic; 2017.
  31. Attri G, et al. Endoscopic third ventriculostomy and simultaneous tumor biopsy in pineal region tumors using the "Single Burr Hole" technique: An analysis of 34 cases. Asian Journal of Neurosurgery. 2020; doi:10.4103/ajns.AJNS_194_20.
  32. Health Education & Content Services. Nerve blocks for headache. Mayo Clinic; 2025.
  33. Health Education & Content Services. Trigger point injections. Mayo Clinic; 2024.
  34. Davis M, et al. Pain and hardware removal after tibial tubercle osteotomy: Incidence, associated factors, and outcomes. Orthopaedic Journal of Sports Medicine. 2025; doi:10.1177/23259671251324481.
  35. Yokoya S, et al. Chronic headache caused by a titanium fixation plate: Report of two cases. Surgical Neurology International. 2017; doi:10.4103/sni.sni_152_17.
  36. ACR Manual on Contrast Media. American College of Radiology. https://www.acr.org/clinical-resources/clinical-tools-and-reference/contrast-manual. Accessed September 23, 2025.