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Victoria E. Clark, M.D., Ph.D.

  1. Neurosurgeon

Dr. Victoria Clark is a neurosurgeon and neurosurgical oncologist at Mayo Clinic in Jacksonville, Florida, where she serves as the State of Florida Endowed Chair of Cancer Research.

She specializes in the surgical treatment of primary and metastatic brain tumors, including meningiomas, glioblastomas, acoustic neuromas, and other complex tumors of the brain and skull base. Her expertise includes awake brain surgery and advanced motor and speech mapping, allowing her to maximize tumor removal while preserving critical neurological function whenever possible.

In addition to her clinical practice, Dr. Clark directs a research laboratory focused on understanding the molecular and genetic mechanisms that drive meningioma development and identifying new targeted therapies for brain tumors. Her research bridges laboratory discovery and patient care, advancing precision medicine and expanding treatment options for patients with both benign and malignant tumors.

Dr. Clark works closely with specialists in neuro-oncology, radiation oncology, neuroradiology, neuropathology and other disciplines to develop personalized treatment plans for each patient. Her approach combines advanced surgical techniques with the latest imaging and brain mapping technologies to provide safe, precise care tailored to each person's diagnosis and goals.

Dr. Clark earned her bachelor's degree in Biochemical Sciences from Harvard University before receiving her M.D. and Ph.D. in Neuroscience from Yale University School of Medicine, where her doctoral research characterized the genomic architecture of meningiomas. She completed her neurosurgery residency at Massachusetts General Hospital and a clinical fellowship in neurosurgical oncology at The University of Texas MD Anderson Cancer Center.

"My goals are to provide an accurate diagnosis, a personalized care plan aligned with each patient's priorities, and timely care," says Dr. Clark. "Caring for someone with a brain tumor is about more than surgery – we have the privilege of supporting our patients and their families throughout their journey, using the latest advances in neurosurgery to help them achieve the best possible outcome."

Outside of medicine, Dr. Clark enjoys spending time at the beach and being with her family.

  1. Acoustic neuroma
  2. Astrocytoma
  3. Benign brain tumor
  4. Brain cancer
  5. Brain metastasis
  6. Brain tumor
  7. Brain tumor-associated epilepsy
  8. Ependymoma
  9. Glioblastoma
  10. Glioma
  11. Glioma-associated epilepsy
  12. Meningioma
  13. Oligoastrocytoma
  14. Oligodendroglioma
  15. Schwannoma
  16. Skull base tumor
  17. Spinal cord tumor
  • Clinical practice focuses on the surgical treatment of primary and metastatic brain tumors, with an emphasis on incorporating technology such as motor and speech mapping to achieve maximal safe resection.
  • Research focuses on meningioma genomics / epigenomics and creating new treatments for meningioma patients.
  1. 2024
    Fellow - Neurosurgical OncologyMD Anderson Cancer Center
  2. 2023
    Visiting Scientist - Post-doctoral research fellowship, Laboratory of Richard A. Young, PhDWhitehead Institute for Biomedical Research - MIT
  3. 2023
    Resident - Neurosurgery Massachusetts General Hospital
  4. 2016
    Doctor of Medicine - Cum LaudeYale University School of Medicine
  5. 2015
    Doctor of Philosophy - Neuroscience, with DistinctionYale University
  6. 2013
    M. Phil - Neuroscience, Distinguished notationYale University
  7. 2008
    BA - Biochemical Sciences, High HonorsHarvard University

Certifications

  1. 2026
    Neurological SurgeryAmerican Board of Neurological Surgery

Awards and honors

  1. 2023
    Second Place, Division of Surgery Clinical Trials Design CourseUniversity of Texas MD Anderson Cancer Center
  2. 2023
    Journal of Neuro-Oncology AwardAANS/CNS Section on Tumors, American Association of Neurological Surgeons
  3. 2023
    Sherry Apple Resident Travel ScholarshipCNS/WINS
  4. 2022
    Senior Resident Clinical Excellence Award MGH Neurosurgery
  5. 2021
    Integra Foundation AwardAmerican Association of Neurological Surgeons
  6. 2020
    NIH/NINDS Research Education Grant (R25); Awarded but declined in order to accept DoD PRCRP Horizon AwardNIH/NINDS
  7. 2016
    MD/PhD Thesis PrizeYale School of Medicine

Professional memberships

  1. 2026 - present
    MemberNeurosurgery Decision Tree Revitalization Project
  2. 2025 - present
    MemberAANS/CNS Section on Tumors
  3. 2025 - present
    MemberFlorida Neurosurgical Society
  4. 2025 - present
    Associate ChairMayo Clinic Platform
  5. 2024 - present
    MemberSociety for Neuro-Oncology
  6. 2024 - present
    MemberAmerican Association of Neurological Surgeons
  7. 2024 - present
    MemberCongress of Neurological Surgeons
  8. 2024 - present
    MemberAANS/CNS Section of Women in Neurosurgery

Publications

Research activities

See a description of research activities.