Biographical summary
Dr. Victoria Clark is a neurosurgeon and neurosurgical oncologist at Mayo Clinic in Jacksonville, Florida, where she serves as the State of Florida Endowed Chair of Cancer Research.
She specializes in the surgical treatment of primary and metastatic brain tumors, including meningiomas, glioblastomas, acoustic neuromas, and other complex tumors of the brain and skull base. Her expertise includes awake brain surgery and advanced motor and speech mapping, allowing her to maximize tumor removal while preserving critical neurological function whenever possible.
In addition to her clinical practice, Dr. Clark directs a research laboratory focused on understanding the molecular and genetic mechanisms that drive meningioma development and identifying new targeted therapies for brain tumors. Her research bridges laboratory discovery and patient care, advancing precision medicine and expanding treatment options for patients with both benign and malignant tumors.
Dr. Clark works closely with specialists in neuro-oncology, radiation oncology, neuroradiology, neuropathology and other disciplines to develop personalized treatment plans for each patient. Her approach combines advanced surgical techniques with the latest imaging and brain mapping technologies to provide safe, precise care tailored to each person's diagnosis and goals.
Dr. Clark earned her bachelor's degree in Biochemical Sciences from Harvard University before receiving her M.D. and Ph.D. in Neuroscience from Yale University School of Medicine, where her doctoral research characterized the genomic architecture of meningiomas. She completed her neurosurgery residency at Massachusetts General Hospital and a clinical fellowship in neurosurgical oncology at The University of Texas MD Anderson Cancer Center.
"My goals are to provide an accurate diagnosis, a personalized care plan aligned with each patient's priorities, and timely care," says Dr. Clark. "Caring for someone with a brain tumor is about more than surgery – we have the privilege of supporting our patients and their families throughout their journey, using the latest advances in neurosurgery to help them achieve the best possible outcome."
Outside of medicine, Dr. Clark enjoys spending time at the beach and being with her family.
Conditions treated
Procedures performed
Interests
- Clinical practice focuses on the surgical treatment of primary and metastatic brain tumors, with an emphasis on incorporating technology such as motor and speech mapping to achieve maximal safe resection.
- Research focuses on meningioma genomics / epigenomics and creating new treatments for meningioma patients.
Mayo Clinic locations
Education
- 2024
Fellow - Neurosurgical OncologyMD Anderson Cancer Center
- 2023
Visiting Scientist - Post-doctoral research fellowship, Laboratory of Richard A. Young, PhDWhitehead Institute for Biomedical Research - MIT
- 2023
Resident - Neurosurgery Massachusetts General Hospital
- 2016
Doctor of Medicine - Cum LaudeYale University School of Medicine
- 2015
Doctor of Philosophy - Neuroscience, with DistinctionYale University
- 2013
M. Phil - Neuroscience, Distinguished notationYale University
- 2008
BA - Biochemical Sciences, High HonorsHarvard University
Activities and honors
Certifications
- 2026
Neurological SurgeryAmerican Board of Neurological Surgery
Awards and honors
- 2023
Second Place, Division of Surgery Clinical Trials Design CourseUniversity of Texas MD Anderson Cancer Center
- 2023
Journal of Neuro-Oncology AwardAANS/CNS Section on Tumors, American Association of Neurological Surgeons
- 2023
Sherry Apple Resident Travel ScholarshipCNS/WINS
- 2022
Senior Resident Clinical Excellence Award MGH Neurosurgery
- 2021
Integra Foundation AwardAmerican Association of Neurological Surgeons
- 2020
NIH/NINDS Research Education Grant (R25); Awarded but declined in order to accept DoD PRCRP Horizon AwardNIH/NINDS
- 2016
MD/PhD Thesis PrizeYale School of Medicine
Professional memberships
- 2026 - present
MemberNeurosurgery Decision Tree Revitalization Project
- 2025 - present
MemberAANS/CNS Section on Tumors
- 2025 - present
MemberFlorida Neurosurgical Society
- 2025 - present
Associate ChairMayo Clinic Platform
- 2024 - present
MemberSociety for Neuro-Oncology
- 2024 - present
MemberAmerican Association of Neurological Surgeons
- 2024 - present
MemberCongress of Neurological Surgeons
- 2024 - present
MemberAANS/CNS Section of Women in Neurosurgery
Publications
Research activities