Cardiac Catheterization Laboratory Overview


Watch Mayo Clinic cardiologists and others discuss many conditions and treatments related to cardiovascular diseases and cardiovascular surgery.

The Cardiac Catheterization Laboratory at Mayo Clinic has been active for more than 50 years. During that time, the staff has been involved in innovation and research in the diagnosis and therapy of cardiovascular diseases. The Cardiac Catheterization Laboratory is equipped with the latest technology and offers a full spectrum of services.

Mayo Clinic was among the first medical centers to pioneer diagnostic techniques via cardiac catheterization. Mayo Clinic has also pioneered the use of several catheter-based therapies, including:

  • Complex coronary artery revascularization
  • Invasive physiologic and hemodynamic assessments
  • Repair of congenital heart defects in children and adults
  • Minimally invasive structural heart disease interventions, including percutaneous valve replacement, such as transcatheter aortic valve replacement, and percutaneous mitral valve repair

The staff in the Cardiac Catheterization Laboratory collaborates with other specialty areas and offers treatment for several conditions, such as carotid artery disease and peripheral artery disease.

At Mayo Clinic's campus in Minnesota, the Cardiac Catheterization Laboratory services are integrated into a clinical setting through the Coronary Artery Disease Clinic. In the Coronary Artery Disease Clinic, you'll consult with doctors on the latest advances relevant to your condition, and you're then treated in the lab soon after. The Valvular Heart Disease Clinic, Pulmonary Hypertension Clinic, Heart Failure Clinic and other subspecialty cardiovascular clinics partner with the Cardiac Catheterization Laboratory to optimize your care.

The Cardiac Catheterization Laboratory offers treatment for children, including infants, at Mayo Clinic's campus in Minnesota. Staff includes specialists trained in treating children with heart conditions (pediatric cardiologists).

Treatment for adults is offered at the Cardiac Catheterization Laboratory at Mayo Clinic's campuses in Arizona, Florida and Minnesota.

After treatment, you'll have the option of continuing your care with a Mayo Clinic doctor, or you may return to your own doctor.

Cardiologists and staff have access to innovative technology that can extend treatment capabilities and reduce risks. The lab's stereotaxis computerized magnetic guidance system allows your doctor to use magnets to more precisely manipulate wires and catheters in your heart, which increases your doctor's ability to access and treat more complex or chronic coronary blockages without surgery. It also allows procedures to be completed in less time, reducing your exposure to radiation.

Technology including intracardiac and intravascular imaging, 3D echocardiogram, and rotational angiography is used to further improve the safety and success rates for complex procedures. Many procedures are now conducted through catheters inserted in arteries in the arm, which helps to improve your safety and comfort.

Doctors may use support systems such as an intra-aortic balloon pump (IABP), left ventricular assist device (LVAD) or a method called extracorporeal membrane oxygenation (ECMO) to support your circulation when your procedure is very complex or your left ventricular function is very poor.


Procedures conducted in the catheterization laboratory to diagnose your condition may include:

  • Constriction and restriction studies
  • Coronary, carotid, renal, peripheral and other forms of angiography
  • Coronary physiology, endothelial and microcirculation assessment (coronary spasm study)
  • Endomyocardial biopsy
  • Evaluation of complex valvular disease
  • Full range of services for people who are having organ transplants, including surveillance biopsies and ultrasound
  • Intracardiac and intravascular ultrasound
  • Left and right heart hemodynamic assessment

Procedures conducted in the catheterization laboratory to treat or manage your condition may include:

Not all procedures may be available at all locations. Please confirm when you request an appointment. Mayo Clinic's Cardiac Catheterization Laboratory in Florida doesn't offer carotid angioplasty and stenting, or procedures to treat some congenital heart conditions.


Mayo Clinic's Cardiac Catheterization Laboratory has a dynamic research program. Several members of the Cardiac Catheterization Laboratory are involved in research and development of new technologies and techniques to expand and improve cardiac catheterization treatment. They conduct research and clinical trials on possible treatments.

Learn more about research in the Cardiovascular Research Center.


To make an appointment, you'll need to be referred by your doctor. Not all services may be available at all locations.

Nationally recognized expertise

Mayo Clinic campuses are nationally recognized for expertise in cardiology and cardiovascular surgery:

  • Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Phoenix/Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, are ranked among the Best Hospitals for heart and heart surgery by U.S. News & World Report.
  • Mayo Clinic Children's Center in Rochester is ranked the No. 1 hospital in Minnesota, and the five-state region of Iowa, Minnesota, North Dakota, South Dakota and Wisconsin, according to U.S. News & World Report's 2022–2023 "Best Children's Hospitals" rankings.
July 23, 2022