1. July 29, 2023

    New pediatric obesity guidelines offer multidisciplinary approach to weight management

    The American Academy of Pediatrics (AAP) released updated guidelines on the evaluation and treatment of children with obesity, recommending a new multidisciplinary model of care.

  2. July 29, 2023

    Long-term outcomes of adult-onset craniopharyngioma

    While treatment outcomes for childhood-onset craniopharyngiomas are well established, a recent Mayo Clinic study looked at adult-onset craniopharyngiomas to improve long-term outcomes for these patients.

  3. April 27, 2023

    Thyroid Eye Disease Clinic offers customized, collaborative approach to treatment

    Mayo Clinic's Thyroid Eye Disease Clinic offers a collaborative approach that helps streamline diagnostic processes and treatment recommendations.

  4. April 25, 2023

    Diabetic ketoacidosis in pregnancy poses mortality risk

    A retrospective, multidisciplinary Mayo Clinic study shows that timely recognition and management of diabetic ketoacidosis (DKA) in pregnancy are crucial for maternal and fetal health.

  5. April 25, 2023

    The legacy of Dr. Henry S. Plummer

    Known for his description of toxic multinodular goiter, called Plummer disease, Henry S. Plummer, M.D., also is credited with designing the hallmark integrated multidisciplinary approach to medical practice that Mayo Cl[...]

  6. April 25, 2023

    Thyroid preservation in differentiated thyroid cancer

    New guidelines advocate for hemithyroidectomy as a viable option for treating some thyroid cancers.

  7. Feb. 07, 2023

    Biochemical parameters to diagnose and treat primary hyperparathyroidism

    Primary hyperparathyroidism is being increasingly diagnosed based on biochemical parameters, rather than overt symptoms and consequences of hypercalcemia.

  8. Feb. 07, 2023

    Hypoglycemia: Overcoming a diagnostic limitation

    Mayo Clinic multidisciplinary team performed analytical validation of a liquid chromatography high resolution accurate mass (LC-HRAM) immunoassay to detect insulin analogs and human insulin.

  9. Feb. 07, 2023

    New third edition: The Mayo Clinic Diet

    Now in its third edition, The Mayo Clinic Diet maps out a weight loss program that helps people learn science-based habits to lose weight and keep it off.

  10. Oct. 29, 2022

    Transition clinic supports teens and young adults with type 1 diabetes

    Mayo Clinic's pediatric and adult endocrinology divisions have joined forces to offer a transition clinic designed to help adolescents and young adults with type 1 diabetes.

  11. Oct. 29, 2022

    Role for stereotactic radiosurgery in pituitary-dependent Cushing syndrome

    A retrospective study shows that stereotactic radiosurgery increases biochemical remission and controls tumor growth in patients with persistent or recurrent Cushing disease.

  12. Oct. 29, 2022

    Q&A: Titrating medications pre-surgery for patients with pheochromocytoma and paraganglioma

    A Mayo Clinic physician provides a basic framework for titrating medications before surgery for patients with pheochromocytoma and paraganglioma.

  13. July 30, 2022

    Outcomes of hyperglycemia in curative treatment of Cushing syndrome

    Mayo Clinic endocrinologists study the degree of postoperative improvement of hyperglycemia following curative surgery for CS. Follow-up protocols are recommended to manage hyperglycemia post-surgery.

  14. July 30, 2022

    Role for cytoreduction surgery in metastatic adrenocortical carcinoma, new study

    Mayo Clinic participates in a retrospective multi-institutional study evaluating cytoreduction surgery of the primary tumor in patients with metastatic ACC.

  15. July 30, 2022

    Renal considerations in transgender and gender-diverse people

    Endocrinologists at Mayo Clinic's Transgender and Intersex Specialty Care Clinic studied changes in kidney function in transgender and gender diverse patients receiving gender-affirming hormone therapy.

  16. April 15, 2022

    Diabetes and COVID-19

    Changes forced by the pandemic may result in deterioration of glucose control for patients with diabetes, as well as increased use of telemedicine and continuous glucose monitoring for inpatient diabetes management.

  17. April 15, 2022

    Osteoporosis in COVID-19

    Mayo specialists share creative clinical solutions to balance the benefits of uninterrupted treatment with the risks of exposure to COVID-19 and its variants.

  18. March 15, 2022

    Mayo Clinic offers fertility preservation for transgender individuals

    At Mayo Clinic's campus in Rochester, Minnesota, reproductive endocrinology and infertility specialists provide services to help transgender individuals preserve fertility for later use.

  19. Feb. 12, 2022

    Role of gut microbiota in obesity and the future of microbiota therapeutics for obesity

    Mayo Clinic researchers summarize the pathogenesis of obesity, the relationship between gut microbiota and obesity, and the future of microbiota-based therapies in obesity management.

  20. Feb. 12, 2022

    Survey examines attitudes about ESG from providers around the world

    A Mayo Clinic survey assessed ESG-related practice trends and preferences of bariatric endoscopists who perform this weight-loss procedure.

  21. Feb. 09, 2022

    Managing complex distal radial fractures

    Mayo Clinic orthopedic surgeons collaborate with other specialists to manage the care of individuals with comorbidities that can increase the risks of wrist surgery.

  22. Feb. 09, 2022

    Managing weight and diabetes before joint replacement surgery

    Reducing the risk of postoperative infections in patients with underlying conditions who have hip or knee replacements requires balancing individuals' desire for pain-relieving joint replacements with surgeons' desire t[...]

  23. Jan. 14, 2022

    Artificial intelligence can identify patients at risk of atrial fibrillation and heart failure in Graves' disease

    Artificial intelligence (AI) helps identify patients with Graves' disease who are at increased risk of developing atrial fibrillation (AF) and heart failure and who may benefit from closer surveillance.

  24. Nov. 23, 2021

    Clinical trials are a way of ‘paying it forward’ to your own community

    Black patients and families are often reluctant to participate in clinical trials. A Mayo Clinic Community Engagement in Research Advisory Board member discusses the importance and benefits of Black participation.

  25. Oct. 26, 2021

    Mayo Clinic clinical trials in patients with tumor-induced osteomalacia

    Research at Mayo Clinic addresses the two main challenges with patients with oncogenic osteomalacia: identification of the disease and the localization of the tumor-producing fibroblast growth factor 23 (FGF23).

  26. Oct. 04, 2021

    Your job or your life, beta cell

    When stressed by obesity and type 2 diabetes, human beta cells respond by making more NBCe1 protein, decreasing those cells' ability to produce and release insulin in response to sugar.

  27. Sept. 07, 2021

    Clue to early indicator of type 1 diabetes identified

    Scientists investigating strategies to restore beta cell function in individuals with type 1 diabetes found that extracellular vesicles encouraged inflammation of pancreatic beta cells in mouse and cell culture models.

  28. Sept. 01, 2021

    Preclinical discovery research leads to better understanding of steroids

    Researchers studying inflammation in the context of diabetes and metabolism found that pharmacological inhibitors of BRD9, which act as inflammatory suppressors alone, are able to synergize with dexamethasone.

  29. Aug. 20, 2021

    Pituitary tumors: Patient-centered care facilitates strong outcomes

    A Mayo Clinic study documented fewer surgical complications and shorter hospital stays for individuals having pituitary tumor surgery at Mayo compared with results from a multicenter study.

  30. Aug. 12, 2021

    Clinical trials from a community perspective: “Authenticity is priceless”

    A community leader in Minneapolis and longtime Mayo Clinic research collaborator shares his thoughts and experiences on the importance of community-engaged research and clinical trials.

  31. July 16, 2021

    LC-MS/MS lowers diagnostic thresholds for androgen-producing tumors or pathological hyperandrogenism in women

    Liquid chromatography with tandem mass spectrometry (LC-MS/MS) provides specific, accurate measurement of total testosterone concentrations in pre- and postmenopausal women with suspected androgen-producing tumor and ov[...]

  32. July 16, 2021

    Very low caloric diet before bariatric surgery reduces perioperative complications

    Research indicates that a very low caloric diet leads to significant preoperative weight loss and reduction in liver volume and a reduction in the complication rate following bariatric surgery.

  33. July 16, 2021

    Safety and efficacy of automated insulin delivery systems for pregnant patients with T1DM

    Researchers at Mayo Clinic in Rochester, Minnesota, are studying automated insulin delivery systems with continuous glucose monitoring in pregnant patients with type 1 diabetes mellitus (T1DM).

  34. July 16, 2021

    Immune checkpoint-induced hypoparathyroidism: A case from the endocrine teaching clinics

    Immune checkpoint inhibitor (ICI) drugs have revolutionized cancer therapy. Mayo Clinic endocrinologists discuss the case of a 76-year-old male with widespread metastatic melanoma who presented with weakness, anorexia a[...]

  35. June 22, 2021

    Overuse of levothyroxine in the United States

    Levothyroxine is commonly prescribed for patients with underactive thyroid glands. A study by Mayo Clinic researchers says the majority of these people were initiated on levothyroxine for mild subclinical hypothyroidism[...]

  36. April 23, 2021

    Microscopic papillary thyroid carcinoma: elevated incidence, reasonable interventions

    Thyroid cancer rates have increased, prompted by higher screening rates and improvements. A Mayo Clinic endocrinologist discusses options of watchful waiting or treatment when thyroid nodules are small.

  37. April 16, 2021

    Diagnosis of a rare endocrine disorder in adulthood: A case from the endocrine teaching clinics

    Jacob D. Kohlenberg, M.D., and Peter J. Tebben, M.D., discuss a rare disorder in a case from the endocrine teaching clinics.

  38. April 16, 2021

    Mayo Clinic Endocrinology and medical society leadership

    Consulting staff at Mayo Clinic are active in local, regional, national and international medical societies.

  39. April 15, 2021

    Elucidating a rare pituitary cancer

    A Mayo Clinic study describes the challenges of diagnosing individuals with this cancer and outlines treatment options.

  40. April 03, 2021

    Transforming cardiovascular treatment for the transgender population

    The Women's Heart Clinic and Transgender and Intersex Specialty Care Clinic at Mayo Clinic partner to provide assessment of the cardiovascular risk of gender-affirming surgery.

  41. Feb. 02, 2021

    Diabetes treatment disparities widespread, room for improvement

    Research indicates that lower income individuals of any race are less likely to receive guideline-recommended treatments for their diabetes and more likely to experience severe hypoglycemia or hyperglycemia events.

  42. Jan. 19, 2021

    Lysosomes help liver cells use fats efficiently

    Nearly 25% of people have abnormally high fat levels in their livers. Researchers studying early stages of fat accumulation found that liver cells metabolize fats more efficiently using cellular processing plants called[...]

  43. Jan. 19, 2021

    Adrenal masses require full investigation at the time of discovery

    Researchers using Rochester Epidemiology Project data have identified a population-based proportion of malignant tumors and other information helpful when discussing management with a patient newly diagnosed with an adr[...]

  44. Jan. 15, 2021

    Selective use of cortical-sparing adrenalectomy for pheochromocytoma

    In cortical-sparing bilateral adrenalectomy, some cortical adrenal tissue is preserved, sparing patients the dependency of exogenous steroids and potential lifelong, life-threatening risk of an adrenal crisis.

  45. Jan. 15, 2021

    Thymic hyperplasia in severe Graves' hyperthyroidism: A case from the endocrine teaching clinics

    Endocrinologist John C. Morris III, M.D., discusses the diagnosis and treatment of a 58-year-old woman with chest pressure, palpitations, insomnia, unintentional weight loss — and no known family history of thyroi[...]

  46. Jan. 15, 2021

    The role of extracellular vesicles in β cell function and pathogenesis of diabetes mellitus

    Research indicates that β cells play a more critical role in their own active demise than previously appreciated, making them prime targets for therapeutic intervention.

  47. Jan. 15, 2021

    Bariatric surgery in children and adolescents at Mayo Clinic

    In Mayo Clinic's adolescent bariatric surgery program, adolescent patients with severe obesity receive education and support to facilitate lifestyle modifications before surgery and close follow-up after.

  48. Dec. 14, 2020

    All adrenal tumors should be investigated, says study

    Researchers describe the epidemiology of adrenal tumors in Olmsted County, Minnesota, based on Rochester Epidemiology Project data. They recommend that all tumors be fully evaluated for malignancy or contributions to ho[...]

  49. Oct. 20, 2020

    A nonadenoma pituitary mass: A case from the endocrine teaching clinics

    William F. Young Jr., M.D., discusses diagnosis and treatment for a patient with a nonadenoma pituitary mass.

  50. Oct. 16, 2020

    Advanced weight management program at Mayo Clinic uses telemedicine to expand services and improve patient outcomes

    Program specialists employ advance triage calls, a weight management blog and video follow-up appointments to address the individual needs of patients who are overweight or obese.

  51. Oct. 16, 2020

    Mayo Clinic's Transgender and Intersex Specialty Care Clinic provides a home base for transgender patients and those with differences of sexual development

    The transgender population faces major challenges in assessing and obtaining appropriate health care. Mayo Clinic's multidisciplinary team provides respectful, appropriate care, including breast and facial procedures an[...]

  52. Oct. 16, 2020

    Select thyroid clinical trials at Mayo Clinic

    Mayo Clinic researchers are investigating therapeutic use of radiofrequency ablation for small papillary thyroid carcinomas. A placebo-controlled interventional trial is testing a new therapy for patients with thyroid e[...]

  53. Aug. 11, 2020

    Oncogenic osteomalacia, pearls from an elusive tumor: A case from the endocrine teaching clinics

    Natalia Genere, M.D., and Robert D. Tiegs, M.D., discuss the care plan for a woman who presented with multiple, nontraumatic fractures discovered during a work-up of diffuse bone pain.

  54. Aug. 08, 2020

    Endocrine practice changes during the COVID-19 pandemic

    Endocrinologists at Mayo Clinic share practice changes to ensure the safety of patients and staff and still provide needed care for patients during the COVID-19 pandemic.

  55. Aug. 08, 2020

    Education in the time of COVID-19

    A Mayo Clinic endocrinology fellow and fellowship program director share perspectives of education during a pandemic.

  56. Aug. 08, 2020

    Call to action produces consensus recommendations around osteoporosis secondary fracture prevention

    Providers from around the world come together to work on new opportunities to increase the screening, diagnosis and treatment of osteoporosis in individuals at high risk to prevent fractures.

  57. April 17, 2020

    Transplant endocrinology at Mayo Clinic

    Mayo Clinic Transplant Center's multidisciplinary providers see recipients of solid organ and bone marrow transplants both pre- and post-transplant to address the unique management challenges of each from an endocrine p[...]

  58. April 17, 2020

    Steroid profiling in the diagnosis of malignant adrenal masses: Cases from the endocrine teaching clinics

    Endocrinologists Shobana Athimulam, M.B.B.S., and Irina Bancos, M.D., discuss the diagnoses and next steps in management of two patients with malignant adrenal tumors.

  59. April 17, 2020

    The Steven A. Smith and Lynda D. Smith Family Fund in Diabetes Care and Education: A parting gift from longest-tenured leader

    The Steven A. Smith and Lynda D. Smith Family Fund in Diabetes Care and Education will help ensure Mayo Clinic Patient Education's commitment to the science of evidence-based patient education.

  60. April 17, 2020

    Mayo Clinic Healthy Living Program for optimization of bone health

    Weight-bearing exercise, strength training and spinal extension exercises help maintain and improve bone density, but many exercise principles need to be taken into consideration to ensure optimal program effectiveness.[...]

  61. Jan. 17, 2020

    Single-site robotic adrenalectomy at Mayo Clinic

    Single-site technology allows for adrenalectomy to be safely performed through a single 2.5-cm incision that accommodates the camera, an assist port and two working hands.

  62. Jan. 17, 2020

    Managing skeletal issues in transgender and gender-nonconforming individuals

    A working model supports that, assuming compliance with hormone therapy, the skeleton should be relatively well protected in both transgender women and transgender men.

  63. Jan. 17, 2020

    Hypophosphatasia: Clinical updates and therapeutic advances

    Most commonly utilized medications for osteoporosis may further impair skeletal mineralization and should be avoided in patients with hypophosphatasia (HPP). Mayo specialists discuss current HPP research and treatment.

  64. Jan. 17, 2020

    Importance of pre-pregnancy care for women with diabetes: A case from the endocrine teaching clinics

    Aoife M. Egan, M.B., B.Ch., Ph.D., and Adrian Vella, M.D., discuss the care program for a patient with type 1 diabetes mellitus who wished to become pregnant.

  65. Jan. 06, 2020

    Out of the shadows: Understanding endocrine cancers

    Mayo Clinic's Endocrine Malignancies Disease Group focuses on patients with less-common endocrine cancers, leading to an optimized approach to thyroid nodules and improved overall survival in anaplastic thyroid cancer.

  66. Dec. 09, 2019

    Artificial Pancreas Keeps Patients Healthier: A Perspective

    A system employing an algorithm-guided, computerized feedback loop to provide a constant and adjusted flow of insulin provides better control than a sensor-augmented pump to keep patients in their glycemic range.

  67. Oct. 22, 2019

    11C-choline PET/CT for parathyroid imaging

    Benefits of carbon-11-choline (11C-choline) positron emission tomography/computerized tomography (PET/CT) over traditional imaging in the treatment of parathyroid adenomas include greater speed and accuracy a[...]

  68. Oct. 22, 2019

    Endocrinologist-directed multidisciplinary hospital nutrition support service

    Mayo Clinic's Nutrition Support Service provides recommendations about whether patients require nutrition support and, if so, which route — gastric or jejunal tube feeding or parenteral nutrition — is optima[...]

  69. Oct. 22, 2019

    Using fluorescence angiography to predict and prevent hypoparathyroidism after thyroid surgery

    Indocyanine green fluorescence angiography provides real-time data to help identify parathyroid glands and assess blood flow and viability during thyroid surgery.

  70. Oct. 22, 2019

    The Mayo Clinic Pediatric Fertility Preservation Program

    The Mayo Clinic Pediatric Fertility Preservation Program offers both ovarian and testicular tissue cryopreservation to children under Institutional Review Board-approved research protocols.

  71. Oct. 22, 2019

    ENPP1 variants associated with autosomal recessive hypophosphatemic rickets type 2: A case from the endocrine teaching clinics

    Anupam Kotwal, M.B.B.S., and Robert A. Wermers, M.D., discuss a case that adds to the body of knowledge about autosomal recessive hypophosphatemic rickets (ARHR) type 2 in adults.

  72. Oct. 22, 2019

    Familial partial lipodystrophy — one size does not fit all: Cases from the endocrine teaching clinic

    Kristen M. Gonzales, M.D., and Vinaya Simha, M.B.B.S., M.D., discuss the genotypic and phenotypic diversity of familial partial lipodystrophy and associated metabolic abnormalities and comorbidities, plus standard manag[...]

  73. Dec. 15, 2018

    Importance of prompt treatment for severe hypercortisolism secondary to ectopic Cushing syndrome: Cases from the endocrine teaching clinics

    Irina Bancos, M.D., and Tiffany M. Cortes, M.D., discuss cases of ectopic Cushing syndrome and the importance of prompt recognition, diagnosis and treatment: If complete resection of the ACTH-secreting neuroendocrine tu[...]

  74. Dec. 15, 2018

    The Mayo Clinic thyroid cancer survivorship program

    A program designed for patients with well-differentiated thyroid cancer who have completed curative-intent treatment provides an individualized survivorship care plan that documents treatment, cancer staging, thyroid ho[...]

  75. Dec. 15, 2018

    Hypertriglyceridemic pancreatitis

    Research indicates it is reasonable to target fasting serum triglyceride below 500 mg/dL to prevent hypertriglyceridemic pancreatitis. Strict adherence to a diet low in saturated fat and refined carbohydrates is likely [...]

  76. Sept. 15, 2018

    Ethanol ablation for the treatment of cystic and predominantly cystic thyroid nodules

    Research indicates that a minimally invasive treatment option, such as percutaneous ethanol injection under ultrasound guidance, generally should be considered for the treatment of symptomatic benign cystic or predomina[...]

  77. Sept. 15, 2018

    Steroid cell tumor of the ovary causing renin-mediated hypertension: A case from the endocrine teaching clinics

    Endocrinologists Oksana Hamidi, D.O., and Todd B. Nippoldt, M.D., discuss the diagnosis and treatment of a 37-year-old woman with a steroid cell tumor — an exceedingly rare sex cord-stromal tumor of the ovary.

  78. Sept. 15, 2018

    Artificial pancreas: The journey continues

    Continuous glucose monitoring that provides real-time measurements every five minutes, insulin pumps and insulin analogs, and accelerated computing speed combine to deliver an artificial pancreas capable of 24/7 modulat[...]

  79. Sept. 15, 2018

    Adrenocortical cancer presenting as postmenopausal bleeding: A case from the endocrine teaching clinics

    Irina Bancos, M.D., and Nana Esi N. Kittah, M.B., Ch.B., discuss the case of a woman who was diagnosed with Lynch syndrome, evaluated for a right adrenal mass and treated for adrenal cortical carcinoma.

  80. Sept. 15, 2018

    Association of yoga exercises and vertebral compression fractures

    Between 2001 and 2014, nearly 30,000 visits to U.S. emergency rooms were related to yoga-associated injuries, with 13 percent of injuries occurring in adults age 65 years or older.

  81. Sept. 15, 2018

    Radiofrequency ablation therapy for large benign thyroid nodules

    Studies confirm that ultrasound-guided thyroid nodule radiofrequency ablation (RFA) is a safe, effective outpatient treatment for patients with symptomatic or steadily growing benign, large, predominantly solid thyroid [...]

  82. Sept. 14, 2018

    Incidentally discovered adrenal masses and subclinical Cushing syndrome

    A clinical trial helps researchers better understand differences in steroid production in patients with subclinical Cushing syndrome, and tie in measured abnormalities with cortisol-induced metabolic changes.

  83. Sept. 14, 2018

    Hypoglycemia — Role for the selective arterial calcium stimulation test

    Use of endoscopic ultrasound, the selective arterial calcium stimulation test (SACST) or both allows specialists to localize or regionalize virtually all insulinomas preoperatively. Once factitious disease has been excl[...]

  84. Sept. 14, 2018

    Recurrent primary hyperparathyroidism in a patient with multiple endocrine neoplasia, type 1: A case from the endocrine teaching clinics

    Recurrent primary hyperparathyroidism (PHPT) is the most common clinical manifestation of patients with multiple endocrine neoplasia, type 1 (MEN1). Naykky M. Singh Ospina, M.D., Robert A. Wermers, M.D., and William F. [...]

  85. Sept. 14, 2018

    Immune checkpoint inhibitors and thyroid dysfunction: A case from the endocrine teaching clinics

    Danae A. Delivanis, M.D., and Mabel Ryder, M.D., explore the use of immune checkpoint inhibitors for patients with advanced, radioiodine refractory thyroid cancer in this case from the endocrine teaching clinics.

  86. Sept. 14, 2018

    An unusual cause of a pituitary mass: A case from the endocrine teaching clinics

    Therapeutic and surgical treatment of patients with pituitary metastasis should be individualized based on presenting symptoms, imaging characteristics, treatment goals and patient preferences. Irina Bancos, M.D., and A[...]

  87. June 13, 2018

    Weight regain after bariatric surgery

    Mayo specialists discuss treatment options available to help patients prevent weight gain after weight-loss surgery, including behavioral intervention, medications and transoral outlet reduction endoscopy.

  88. June 12, 2018

    Thyroid storm: A case from the endocrine teaching clinics

    Diane Donegan, M.B., B.Ch., and Marius N. Stan, M.D., discuss diagnosis and treatment of thyroid storm, including aggressive nonsurgical management of hyperthyroidism, use of extracorporeal membrane oxygenation for card[...]

  89. June 12, 2018

    Ratio of 25(OH)D-to-24,25(OH)2D: A new test to confirm 24-hydroxylase (CYP24A1) deficiency as the cause of hypercalcemia

    Researchers found that the ratio of 25(OH)D-to-24,25(OH)2D is necessary to estimate the calculation of vitamin D 24-hydroxylase enzyme activity to confirm 24-hydroxylase (CYP24A1) deficiency as the c[...]

  90. June 09, 2018

    A flushing disorder: A case from the endocrine teaching clinics

    Shrikant U. Tamhane, M.B.B.S., and William F. Young Jr., M.D., discuss the case of a patient with flushing disorder. After normal laboratory tests, ultrasound showed a suspicious nodule in the patient's midright thyroid[...]

  91. June 09, 2018

    An inconspicuous pheochromocytoma: A case from the endocrine teaching clinics

    Neurofibromatosis 1 (NF1) has a high prevalence of asymptomatic pheochromocytoma; hypertension is the most common symptom. Endocrinologists Todd B. Nippoldt, M.D., and Anu Sharma, M.B.B.S., discuss a case and recommenda[...]

  92. June 09, 2018

    Diagnostic approach to disorders of extraskeletal bone formation

    Clinical diagnosis of genetic forms of heterotopic ossification is supported by associated features of the specific conditions and molecular confirmation of involvement of known genes.

  93. May 25, 2018

    Thyroid eye disease clinic — The Mayo Clinic Model

    At Mayo Clinic, patients with Graves' orbitopathy (GO) are seen by an endocrinologist, ophthalmologist and ENT surgeon. The multidisciplinary team works to minimize or eliminate postoperative eye misalignment and double[...]

  94. May 25, 2018

    Functioning gonadotroph macroadenoma causing ovarian hyperstimulation: A case from the endocrine teaching clinics

    Endocrinologists Haleigh A. James, M.D., and Todd B. Nippoldt, M.D., discuss a case that illustrates the clinical course of a functioning gonadotroph adenoma — a rare pituitary tumor that secretes biologically act[...]

  95. May 25, 2018

    Senescent cells: Promising anti-aging targets for health span extension and the treatment of osteoporosis

    Cellular senescence, a cell fate that involves an irreversible state of replicative arrest induced by stress, has emerged as a promising fundamental aging mechanism that could be targeted to treat multiple diseases of a[...]

  96. May 22, 2018

    An emerging connection between circadian rhythm disruption and type 2 diabetes mellitus

    Researchers explore the molecular and physiological mechanisms responsible for circadian disruption-associated risk of type 2 diabetes mellitus (T2DM), which hold potential for contributing to development of novel thera[...]

  97. May 22, 2018

    Novel therapeutic approach for ectopic Cushing syndrome: A case from the endocrine teaching clinics

    Endocrinologists Irina Bancos, M.D., and Jad Sfeir, M.D., discuss the case of a woman with corticotropin (ACTH)-dependent Cushing syndrome. Treatment involved a minimally invasive procedure targeting the lung lesion usi[...]

  98. April 21, 2018

    A missed parathyroid adenoma: A case from the endocrine teaching clinics

    A case from the endocrine teaching clinics affirms that ectopic parathyroid tissue should be considered in patients with persistent primary hyperparathyroidism. - Resource Center for Medical Professionals including clin[...]

  99. July 11, 2017

    Hypoparathyroidism: Causes, presentation and advances in treatment

    Approval of the recombinant human parathyroid hormone rhPTH(1-84), currently an expensive drug, for treatment of hypoparathyroidism has stimulated research into new treatment modalities and development of PTH analogues.[...]

  100. April 11, 2017

    Metformin revisited

    Metformin continues to dominate as an oral therapeutic agent for type 2 diabetes mellitus (T2DM), both as monotherapy and in combination with other medications. Yet after 50 years, its mechanism of action isn't fully un[...]

  101. Feb. 25, 2017

    Weight gain in women at midlife: Unique issues in management and the role of menopausal hormone therapy

    Menopausal hormone therapy (MHT) is the most effective treatment for menopausal vasomotor symptoms, but it cannot be recommended as a therapy to help women at midlife lose weight.

  102. Dec. 03, 2016

    Preventing type 2 diabetes mellitus: Insights from genetic studies

    To date there are approximately 65 common genetic variants reproducibly associated with type 2 diabetes mellitus. The greatest risk is associated with variation in the gene TCF7L2.

  103. Sept. 07, 2016

    Addressing the challenges of transgender health care

    The Mayo Clinic Transgender and Intersex Specialty Care Clinic provides tips for addressing the mental health, hormonal and surgical needs of transgender patients and those with differences of sexual development, or int[...]

  104. Sept. 07, 2016

    Intragastric balloon: A re-emerging approach for obesity

    The intragastric balloon aids weight loss in patients with mild to moderate obesity, but lifestyle changes including behavior modification, exercise and a healthy diet are crucial for maintaining weight loss once the de[...]

  105. May 07, 2016

    Bariatric surgery in adolescents

    Adolescents with a BMI ≥ 35 kg/m2 and a severe comorbidity, or a BMI ≥ 40 kg/m2 with more minor comorbidities, may be candidates for bariatric surgery.

  106. April 08, 2016

    Assessment of bone strength in vivo in humans: A novel diagnostic tool for osteoporosis

    VirtuOst technology uses clinical computerized tomography scans obtained for any purpose to obtain noninvasive measures of bone strength at the spine or hip using finite element analysis (FEA).

  107. Nov. 25, 2015

    New tools to predict fracture risk

    Bone mass and quality decline with age, leading to compromised strength and increased fracture risk. Trabecular bone score (TBS) uses standard dual energy X-ray absorptiometry to measure how well-structured the trabecul[...]

  108. Nov. 25, 2015

    Postural orthostatic tachycardia syndrome and chronic fatigue in adolescents: Working toward recovery

    Mayo's Pediatric Pain Rehabilitation Center offers a program for teens with postural orthostatic tachycardia syndrome (POTS) that helps participants focus on increasing function, tapering off pain medications, and build[...]

  109. Nov. 25, 2015

    Evaluating the efficacy of intervertebral disk regeneration with stem cells in animals

    More than 90 percent of people older than 50 experience intervertebral disk (IVD) degeneration. In animal studies, stem cell transplantation to the disk has shown promise in decelerating or arresting the degenerative pr[...]

  110. Sept. 01, 2015

    Lipodystrophy syndromes: New treatment, newer questions

    Advances of understanding of the molecular mechanisms of fat loss and its treatment also provide valuable insight into adipose tissue biology and the pathophysiology of other common obesity-related metabolic disorders.

  111. May 29, 2015

    The role of focused parathyroidectomy

    Focused parathyroidectomy entails an image-guided exploration of a single parathyroid adenoma with the use of intraoperative parathyroid hormone monitoring to define a biochemical cure. Smaller incisions often result in[...]

  112. March 28, 2015

    Primary aldosteronism: The role of adrenal venous sampling

    For patients with primary aldosteronism who want to pursue surgical treatment rather than pharmacological therapy, adrenal venous sampling (AVS) is the key diagnostic step. At experienced centers, the complication rate [...]

  113. March 05, 2015

    Retroperitoneoscopic adrenalectomy: A useful surgical approach in select patients

    Retroperitoneoscopic adrenalectomy (RPA) allows direct access to the retroperitoneum and adrenal gland without the need for intra-abdominal organ mobilization. RPA involves placing the patient in prone position. The adr[...]

  114. Jan. 31, 2015

    Advances in endoscopic pituitary surgery

    Use of an expanded endoscopic approach allows surgeons to visualize difficult-to-see regions in the sella and enhances the opportunity for a complete pituitary tumor resection.

  115. Sept. 10, 2014

    Ultrasound-guided percutaneous ethanol ablation of neck nodal metastases in patients with papillary thyroid carcinoma

    Cost-effective ultrasound-guided percutaneous ethanol ablation may be generally incorporated into the management of NNM in patients with advanced localized papillary thyroid cancer not amenable to conventional retreatme[...]

  116. April 24, 2014

    The Thyroid Nodule Clinic

    The Thyroid Nodule Clinic provides a one-stop thyroid nodule evaluation that includes a focused clinical assessment, ultrasound evaluation and fine-needle aspiration — all typically performed within a single appoi[...]

  117. Sept. 05, 2012

    Skeletal health in adult patients with cancer

    The skeletal effects of cancer-associated bone loss have become more important due to improved patient survival rates and longevity. Pharmacological interventions, counseling about high-risk activities, physical therapy[...]

  118. Sept. 05, 2012

    Future therapy for Graves' ophthalmology

    No uniformly effective therapy exists for Graves' ophthalmology. Insights into the important role of TSH receptor and TRAb in the development of the tissue remodeling characteristic of the disease suggest new approaches[...]