Marfan Syndrome and Thoracic Aorta Clinic Overview


Watch Mayo Clinic cardiologists and others discuss many conditions and treatments related to cardiovascular diseases and cardiovascular surgery.

The Marfan Syndrome and Thoracic Aorta Clinic provides comprehensive, specialized care for people with suspected or known heritable aortic disorders, including Marfan syndrome, Loeys-Dietz syndrome, vascular Ehlers-Danlos syndrome and other connective tissue disorders, bicuspid aortopathy, familial thoracic aortic aneurysm, and dissection syndromes.

New medical and surgical treatments are being developed for Marfan syndrome and related disorders. Advances in medical and surgical care have greatly improved life expectancy for people with these conditions. Proper treatment requires accurate genetic evaluation as medical and surgical decision-making is increasingly driven by genetic diagnosis.

In the Marfan Syndrome and Thoracic Aorta Clinic, a multidisciplinary team of doctors trained in heart conditions (cardiologists), heart and blood vessel surgery (cardiovascular surgeons), cardiac imaging, hereditary conditions (medical geneticists), eye conditions (ophthalmologists), bone and muscle surgery (orthopedic surgeons), and other areas collaborate to provide your care.

Doctors trained in treating children with medical conditions (pediatricians) and heart conditions (pediatric cardiologists) provide care for children with Marfan syndrome and related disorders at Mayo Clinic's campus in Minnesota.

You'll work closely with a team of specialists to create a treatment plan that meets your individual needs. Your treatment may include medications, genetic and reproductive counseling, lifestyle changes, and possibly surgery.


Conditions diagnosed and treated at the Marfan Syndrome and Thoracic Aorta Clinic include:

Your comprehensive care plan may involve the following services:

  • Noninvasive cardiovascular imaging
  • Advanced cardiovascular biomarker testing
  • Genetic testing and counseling
  • Risk stratification
  • Advanced cardiovascular lab testing
  • Medical treatments
  • Cardiac surgery

Depending on your situation, your treatment may also involve care for musculoskeletal system problems, vision problems and chronic pain.


Mayo Clinic researchers are working to improve diagnostic tests, genetic testing and treatment of Marfan syndrome. Doctors also research new surgical techniques and the outcomes of surgical treatments for Marfan syndrome.


You may be referred by your primary doctor, or you may make an appointment without a referral. Not all services may be available at all locations. Please confirm when you request an appointment.

July 23, 2022