Risks By Mayo Clinic Staff Print Side effects of chemotherapy drugs can be significant. Each drug has different side effects, and not every drug causes every side effect. Ask your doctor about the side effects of the particular drugs you'll receive. Side effects that occur during chemotherapy treatmentCommon side effects of chemotherapy drugs include: Nausea Vomiting Diarrhea Hair loss Loss of appetite Fatigue Fever Mouth sores Pain Constipation Easy bruising Many of these side effects can be prevented or treated. Most side effects subside after treatment ends. Long-lasting and late-developing side effectsChemotherapy drugs can also cause side effects that don't become evident until months or years after treatment. Late side effects vary depending on the chemotherapy drug but can include: Damage to lung tissue Heart problems Infertility Kidney problems Nerve damage (peripheral neuropathy) Risk of a second cancer Ask your doctor if you have a risk of any late side effects. Ask what signs and symptoms you should be alert for that may signal a problem. Request an Appointment at Mayo Clinic Why it's doneHow you prepare April 27, 2017 Print Share on: FacebookTwitter References Chemotherapy and you: Support for people with cancer. National Cancer Institute. https://www.cancer.gov/publications/patient-education/chemo-and-you. Accessed Feb. 2, 2017. Niederhuber JE, et al., eds. Cancer pharmacology. In: Abeloff's Clinical Oncology. 5th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2014. http://www.clinicalkey.com. Accessed Feb. 2, 2017. What to expect when having chemotherapy. Cancer.Net. http://www.cancer.net/navigating-cancer-care/how-cancer-treated/chemotherapy/what-expect-when-having-chemotherapy. Accessed Feb. 2, 2017. Cyclophosphamide (Cytoxan). American College of Rheumatology. http://www.rheumatology.org/I-Am-A/Patient-Caregiver/Treatments/Cyclophosphamide-Cytoxan. Accessed Feb. 2, 2017. Riggin EA. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Oct. 6, 2016. RelatedGet ready for possible side effects of chemotherapyChemo TargetsChemotherapy and sex: Is sexual activity OK during treatment?Magic mouthwashGinger for nausea: Does it work?Chemotherapy and hair loss: What to expect during treatmentChemotherapy nausea and vomiting: Prevention is best defenseEating during cancer treatment: Tips to make food tastierCancer treatmentPet therapySelf-Image During CancerFertility preservationCancer treatment mythsPICC line placementCancer treatment for men: Possible sexual side effectsChemotherapy side effects: A cause of heart disease?Nasopharyngeal carcinomaMelanomaProstate cancerMale breast cancerHodgkin's lymphomaMultiple myelomaNon-Hodgkin's lymphomaAcute myelogenous leukemia (AML)Recurrent breast cancerInvasive lobular carcinomaCancerVulvar cancerGallbladder cancerHairy cell leukemiaLeukemiaLung cancerBone metastasisMesotheliomaOvarian cancerCastleman diseaseSkin cancerAcute lymphocytic leukemiaSoft tissue sarcomaCarcinoid syndromeThroat cancerZollinger-Ellison syndrome ChemotherapyOverviewProcedure detailsRequest an appointmentWhy it's doneRisksHow you prepareWhat you can expectResultsMayo Clinic's approachThe Mayo Clinic experience & patient storiesDepartments & specialtiesExpertise & rankingsLocations, travel & lodgingClinical trialsResearchCosts & insuranceMore aboutIn-DepthExpert AnswersExpert BlogMultimediaResourcesNews from Mayo Clinic Advertisement Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Advertising & Sponsorship Policy Opportunities Ad Choices Mayo Clinic Store Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. The Mayo Clinic Diet BookMedical News From a Trusted SourceMayo Clinic on Healthy AgingA New Perspective on Alzheimer'sThe Mayo Clinic Diet Online Procedure detailsRequest an appointmentMayo Clinic's approachThe Mayo Clinic experience & patient storiesDepartments & specialtiesExpertise & rankingsLocations, travel & lodgingClinical trialsResearchCosts & insurance PRC-20248525 Patient Care & Health Information Tests & Procedures Chemotherapy