Overview

Irritable bowel syndrome (IBS) is a common disorder that affects the large intestine. Signs and symptoms include cramping, abdominal pain, bloating, gas, and diarrhea or constipation, or both. IBS is a chronic condition that you'll need to manage long term.

Only a small number of people with IBS have severe signs and symptoms. Some people can control their symptoms by managing diet, lifestyle and stress. More-severe symptoms can be treated with medication and counseling.

IBS doesn't cause changes in bowel tissue or increase your risk of colorectal cancer.

Symptoms

The signs and symptoms of IBS vary but are usually present for a long time. The most common include:

  • Abdominal pain, cramping or bloating that is related to passing a bowel movement
  • Changes in appearance of bowel movement
  • Changes in how often you are having a bowel movement

Other symptoms that are often related include bloating, increased gas or mucus in the stool.

When to see a doctor

See your doctor if you have a persistent change in bowel habits or other signs or symptoms of IBS. They may indicate a more serious condition, such as colon cancer. More-serious signs and symptoms include:

  • Weight loss
  • Diarrhea at night
  • Rectal bleeding
  • Iron deficiency anemia
  • Unexplained vomiting
  • Difficulty swallowing
  • Persistent pain that isn't relieved by passing gas or a bowel movement

Causes

The precise cause of IBS isn't known. Factors that appear to play a role include:

  • Muscle contractions in the intestine. The walls of the intestines are lined with layers of muscle that contract as they move food through your digestive tract. Contractions that are stronger and last longer than normal can cause gas, bloating and diarrhea. Weak intestinal contractions can slow food passage and lead to hard, dry stools.
  • Nervous system. Abnormalities in the nerves in your digestive system may cause you to experience greater than normal discomfort when your abdomen stretches from gas or stool. Poorly coordinated signals between the brain and the intestines can cause your body to overreact to changes that normally occur in the digestive process, resulting in pain, diarrhea or constipation.
  • Severe infection. IBS can develop after a severe bout of diarrhea (gastroenteritis) caused by bacteria or a virus. IBS might also be associated with a surplus of bacteria in the intestines (bacterial overgrowth).
  • Early life stress. People exposed to stressful events, especially in childhood, tend to have more symptoms of IBS.
  • Changes in gut microbes. Examples include changes in bacteria, fungi and viruses, which normally reside in the intestines and play a key role in health. Research indicates that the microbes in people with IBS might differ from those in healthy people.

Triggers

Symptoms of IBS can be triggered by:

  • Food. The role of food allergy or intolerance in IBS isn't fully understood. A true food allergy rarely causes IBS. But many people have worse IBS symptoms when they eat or drink certain foods or beverages, including wheat, dairy products, citrus fruits, beans, cabbage, milk and carbonated drinks.
  • Stress. Most people with IBS experience worse or more-frequent signs and symptoms during periods of increased stress. But while stress may aggravate symptoms, it doesn't cause them.

Risk factors

Many people have occasional signs and symptoms of IBS. But you're more likely to have the syndrome if you:

  • Are young. IBS occurs more frequently in people under age 50.
  • Are female. In the United States, IBS is more common among women. Estrogen therapy before or after menopause also is a risk factor for IBS.
  • Have a family history of IBS. Genes may play a role, as may shared factors in a family's environment or a combination of genes and environment.
  • Have anxiety, depression or other mental health issues. A history of sexual, physical or emotional abuse also might be a risk factor.

Complications

Chronic constipation or diarrhea can cause hemorrhoids.

In addition, IBS is associated with:

  • Poor quality of life. Many people with moderate to severe IBS report poor quality of life. Research indicates that people with IBS miss three times as many days from work as do those without bowel symptoms.
  • Mood disorders. Experiencing the signs and symptoms of IBS can lead to depression or anxiety. Depression and anxiety also can make IBS worse.

Irritable bowel syndrome care at Mayo Clinic

Oct. 15, 2020
  1. Hadjivasilis A, et al. New insights into irritable bowel syndrome: From pathophysiology to treatment. Annals of Gastroenterology. 2019; doi:10.20524/aog.2019.0428.
  2. Irritable bowel syndrome. National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/digestive-diseases/irritable-bowel-syndrome/all-content. Accessed Aug. 28, 2020.
  3. Kellerman RD, et al. Irritable bowel syndrome. In: Conn's Current Therapy 2020. Elsevier; 2020. https://www.clinicalkey.com. Accessed Aug. 28, 2020.
  4. Feldman M, et al. Irritable bowel syndrome. In: Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 11th ed. Elsevier; 2021. https://www.clinicalkey.com. Accessed Aug. 28, 2020.
  5. Irritable bowel syndrome. American College of Gastroenterology. https://gi.org/topics/irritable-bowel-syndrome/. Accessed Aug. 28, 2020.
  6. 6 tips: IBS and complementary health practices. National Center for Complementary and Integrative Health. https://www.nccih.nih.gov/health/tips/tips-ibs-and-complementary-health-practices. Accessed Aug. 28, 2020.
  7. Irritable bowel syndrome. Canadian Society of Intestinal Research. https://badgut.org/information-centre/a-z-digestive-topics/ibs/. Accessed Aug. 28, 2020.
  8. Brown AY. Allscripts EPSi. Mayo Clinic. June 24, 2020.
  9. Kashyap PC (expert opinion). Mayo Clinic. Sept. 21, 2020.

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