Heart transplant

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Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

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Displaying 1-2 out of 2 doctors available

Last Name Initial: L

  1. Juan Carlos Leoni Moreno, M.D.

    Juan Carlos Leoni Moreno, M.D.

    1. Transplant Cardiologist
    1. Jacksonville, FL
    Areas of focus:

    Heart transplant, Mechanical circulatory support device implantation, Post-transplant long-term care, Pre-transplant ev...aluation, Left ventricular assist device implantation, Congenital heart defects in adults, Heart failure, Cardiomyopathy, Amyloidosis, Myocarditis, Sarcoidosis, Heart transplant complication, Cardiogenic shock

  2. Melissa A. Lyle, M.D.

    Melissa A. Lyle, M.D.

    1. Transplant Cardiologist
    1. Jacksonville, FL
    Areas of focus:

    Heart transplant, Mechanical circulatory support device implantation, Post-transplant long-term care, Pre-transplant ev...aluation, Transesophageal echocardiogram, Transthoracic echocardiogram, Congenital heart defects in adults, Heart failure, Cardiomyopathy, Amyloidosis, Cardiac amyloidosis, Myocarditis, Hypertrophic cardiomyopathy, Cardiac sarcoidosis, Sarcoidosis, Heart transplant complication, Cardiogenic shock

Research

Mayo Clinic researchers in the Transplant Center conduct ongoing studies and clinical trials to improve surgical procedures, improve outcomes and care for people who need transplants. Researchers also study alternative therapies for people who might be able to use a heart transplant alternative.

Areas of research include:

  • Cardiac regenerative therapies.
  • Genetics and potential treatments for hypoplastic left heart syndrome, a rare congenital heart defect.
  • Biomarkers and genetics to individualize therapy.
  • New or improved surgical procedures.
  • Selecting and treating heart transplant recipients.
  • Therapeutic approaches to prolong graft survival.
  • Managing immunosuppressive medicines after transplant.
  • New immunosuppressant medicines.
  • Outcomes after heart transplants.
  • Blood tests to monitor for rejection.
  • Ventricular assist devices.
  • Alternative therapies for people who may not need heart transplants.
  • Wellness coaching for caregivers and transplant recipients.
  • Transplanting living organs from one species to another, a process called xenotransplantation.
  • Gene therapy.

Publications

See a list of publications about heart transplant by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

By Mayo Clinic Staff

Heart transplant care at Mayo Clinic

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AboutCare at Mayo Clinic
July 08, 2026
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  1. Libby P, et al., eds. Cardiac transplantation. In: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed July 13, 2025.
  2. Goldman L, et al., eds. Heart failure: Epidemiology, pathobiology, and diagnosis. In: Goldman-Cecil Medicine. 27th ed. Elsevier, 2024. https://www.clinicalkey.com. Accessed July 13, 2025.
  3. Fuster V, et al., eds. Mechanical circulatory support and heart transplantation in severe heart failure. In: Fuster and Hurst's The Heart. 15th ed. McGraw Hill; 2022. https://accessmedicine.mhmedical.com. Accessed July 13, 2025.
  4. Kliegman R, et al., eds. Heart failure. In: Nelson Textbook of Pediatrics. 22nd ed. Elsevier, 2025. https://www.clinicalkey.com. Accessed July 13, 2025.
  5. Duarte VE, et al. Multi-organ transplantation in adult congenital heart disease: Navigating the unique challenges of a distinct patient population. Methodist DeBakey Cardiovascular Journal. 2025; doi:10.14797/mdcvj.1576.
  6. Sellke FW, et al., eds. Heart transplantation. In: Sabiston and Spencer Surgery of the Chest. 10th ed. Elsevier, 2024. https://www.clinicalkey.com. Accessed July 14, 2025.
  7. Garden OJ, et al., eds. Transplantation surgery. In: Principles and Practice of Surgery. 8th ed. Elsevier, 2023. https://www.clinicalkey.com. Accessed July 14, 2025.
  8. Libby P, et al., eds. Mechanical circulatory support. In: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed July 14, 2025.
  9. Rezaei N, ed. Immunosuppressive drugs. In: Encyclopedia of Infection and Immunity. Elsevier; 2022. https://sciencedirect.com. Accessed July 8, 2025.
  10. Elsevier Point of Care. Clinical Overview: Preventive care for patients receiving immunosuppressive therapy after transplant. https://www.clinicalkey.com. Accessed July 7, 2025.
  11. American Society of Transplantation. Caregiver Toolkit: Heart transplants. https://www.myast.org/caregiver-toolkit/heart. Accessed July 13, 2025.
  12. Elsevier Point of Care. Clinical Overview: Cardiac transplant. https://www.clinicalkey.com. Accessed July 17, 2025.
  13. Pham MX. Heart transplantation in adults: Prognosis. https://www.uptodate.com/contents/search. Accessed July 17, 2025.
  14. Snyder JJ, et al. Stakeholders' perspectives on transplant metrics: The 2022 Scientific Registry of Transplant Recipients' consensus conference. American Journal of Transplantation. 2023; doi:10.1016/j.ajt.2023.03.012.
  15. Mancini D. Heart transplantations in adults: Indications and contraindications. https://www.uptodate.com/contents/search. Accessed July 17, 2025.
  16. International Society for Heart and Lung Transplantation. International Society for Heart and Lung Transplantation guidelines for the evaluations and care of cardiac transplant candidates­­–2024. The Journal of Heart and Lung Transplantation. 2024; doi:10.1016/j.healun.2024.05.010.
  17. International Society for Heart and Lung Transplantation. International Society for Heart and Lung Transplantation (ISHLT) guidelines for the care of heart transplant recipients. The Journal of Heart and Lung Transplantation. 2023; doi:10.1016/j.healun.2022.10.015.
  18. Gropper MA, et al. Anesthesia for cardiac surgical procedures. In: Miller's Anesthesia. 10th ed. Elsevier, 2025. https://www.clinicalkey.com. Accessed July 19, 2025.
  19. Heidenreich PA, et al.. 2022 AHA/ACC/HFSA guideline for the management of heart failure. Journal of the American College of Cardiology. 2022; doi:10.1016/j.jacc.2021.12.012.
  20. Chrysakis N, et al. Heart transplantation. Journal of Clinical Medicine. 2024; doi:10.3390/jcm13020558.
  21. Gerlach RM. Anesthesia for heart transplantation. https://www.uptodate.com/contents/search. Accessed July 19, 2025.
  22. Hwang NC, et al. Review of postoperative care for heart transplant recipients. Journal of Cardiothoracic and Vascular Anesthesia. 2023; doi:10.1053/j.jvca.2022.09.083.
  23. Eisen HJ. Heart transplantation in adults: Diagnosis of allograft rejection. https://www.uptodate.com/contents/search. Accessed July 19, 2025.
  24. Kuntz K, et al. Adherence in transplantation. Current Opinion in Organ Transplantation. 2022; doi:10.1097/MOT.0000000000001025.
  25. Kankaya EA, et al. Evaluating the relationship between medication adherence, dietary practices, and physical activity in heart transplant recipients. Clinical Transplantation. 2025; doi:10.1111/ctr.70125.
  26. Buja LM, et al., eds. Pathology of cardiac transplantation. In: Cardiovascular Pathology. 5th ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed July 19, 2025.
  27. American Heart Association. Core components of cardiac rehabilitation programs: 2024 update: A scientific statement from the American Heart Association and the American Association of Cardiovascular and Pulmonary Rehabilitation. Circulation. 2024; doi:10.1161/CIR.0000000000001289.
  28. Giordano T, et al. Assessing how a transplant hospitality house for patients and families can promote wellbeing. Progress in Transplantation. 2021; doi:10.1177/15269248211003561.

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Heart transplant