Mayo Clinic's approach

Mayo Clinic doctors have extensive experience using bone marrow transplants to treat a variety of conditions, including cancers. Mayo Clinic offers bone marrow transplants for adults and children using the patient's own cells (autologous transplant), cells from a donor (allogeneic transplant) or using cells from an umbilical cord (cord blood transplant).

People who choose Mayo Clinic for their care receive comprehensive, compassionate and personalized attention from doctors and staff who are committed to providing exactly the care they need.

Teamwork

At Mayo Clinic, doctors who specialize in blood diseases (hematologists) form a multidisciplinary team with other experts to provide personalized, whole-person care to adults and children undergoing bone marrow transplants.

Image for Bone Marrow transplant

Your transplant team may include hematologists, cancer specialists (oncologists), mental health specialists (psychologists and psychiatrists), a bone marrow transplant scheduling coordinator, transfusion medicine nurses, trained and specialized nurses, physician assistants, social workers, a nurse coordinator, a clinical nurse specialist, a dietitian, pharmacists, a chaplain and a child life specialist for children undergoing bone marrow transplant.

Children and adolescents undergoing bone marrow transplants receive care at the Children's Center at Mayo Clinic's campus in Minnesota. At Mayo Clinic's campus in Arizona, pediatric experts collaborate with the Phoenix Children's Hospital to provide care to young patients. Together the two oversee a single bone marrow transplant program for children. Pediatric patients receive care from Mayo Clinic specialists in Florida through a partnership with Nemours Children's Specialty Care and Wolfson Children's Hospital.

Image of Mayo Clinic doctors and staff working together Working together

Mayo Clinic doctors and staff collaborate to provide you with exactly the care you need.

Experience

Mayo Clinic doctors have extensive experience performing bone marrow transplants for adults and children with a variety of cancerous and noncancerous diseases. Each year, more than 700 people undergo bone marrow transplants at Mayo Clinic.

The first bone marrow transplant at Mayo Clinic occurred in 1963. Bone marrow transplant procedures are performed by Mayo Clinic doctors in Arizona, Florida and Minnesota.

The long history of bone marrow transplants performed at Mayo Clinic means that doctors are prepared with the knowledge and resources to provide you with expert, personalized care.

Image of staff providing compassionate care Providing compassionate care

Mayo Clinic experts draw on their extensive experience to provide personalized care to people considering bone marrow transplant

Bringing research advances to patient care

Mayo Clinic doctors and scientists are involved in cutting-edge research that allows them to apply the latest advances to patient care.

Innovations include:

  • Haploidentical transplant to use stem cells from donors who aren't perfect matches. Research is helping doctors understand how to reduce the risk of complications and improve recovery for people whose stem cell donors aren't perfect matches.
  • Reduced-intensity conditioning to use lower doses of chemotherapy and radiation before a transplant. Researchers are studying new conditioning regimens that will allow older people and those who aren't healthy enough for conditioning to undergo bone marrow transplants.
  • Cord blood transplant using stored and frozen umbilical cord blood. There are fewer stem cells in cord blood, but those stem cells can grow more blood cells than can those collected from bone marrow. Using cells from cord blood reduces the risk of graft-versus-host disease. Researchers are identifying the best ways to use cord blood for bone marrow transplants.
  • Expanding indications for bone marrow transplant to use this treatment for a wider variety of conditions, including complicated and rare diseases.

At Mayo Clinic, some bone marrow transplants are performed as hospital-based outpatient procedures, which reduces the amount of time you'll need to spend in the hospital.

Nationally recognized expertise

Mayo Clinic bone marrow transplant specialists are respected for their knowledge, experience and expertise.

Mayo Clinic in Rochester, Minn., and Mayo Clinic in Phoenix/Scottsdale, Ariz., are ranked among the Best Hospitals for cancer by U.S. News & World Report. Mayo Clinic in Jacksonville, Fla., is ranked highly performing for cancer by U.S. News & World Report.

    The Mayo Clinic experience and patient stories

    Our patients tell us that the quality of their interactions, our attention to detail and the efficiency of their visits mean health care like they've never experienced. See the stories of satisfied Mayo Clinic patients.

    1. Fighting Leukemia, Then Joining the Team

      When Nicklaus Lego was diagnosed with an aggressive blood and bone marrow cancer, he was told his chances of survival were slim. To beat the disease, Nic needed a bone marrow transplant and an expert medical team. At Mayo Clinic, Nic found both. And in the process, he discovered a new life's mission. As a [...]

    2. Looking to the Future Despite Multiple Myeloma

      Linda Kent has been living with multiple myeloma for seven years. After having only a partial response to the treatment she was on when she lived in Idaho, she moved to Florida and began a different treatment regimen at Mayo Clinic. Today, Linda is more hopeful than ever as she begins new treatment as part [...]

    3. Comprehensive Care for a Complex Diagnosis Offers New Hope

      When Travis Morris first came to Mayo Clinic, he had no explanation for the debilitating symptoms that had brought him to Rochester, Minnesota. By the time he left, however, Travis not only had a diagnosis, he had a treatment plan that's now helping to significantly improve his quality of life. Travis Morris had waited a [...]

    4. Shocking Diagnosis Leads to a New Focus on Joy

      Andrea Borg was stunned to learn she had a life-threatening form of leukemia. But she persevered through demanding treatment regimens that ultimately put her cancer in remission. Today Andrea is focused on supporting others going through similar health challenges.? While perishable grocery items like milk and salmon certainly have expiration dates, Andrea Borg never expected [...]

    5. Tailored Treatment for Multiple Myeloma Yields Ideal Results

      When Diane Thompson came to Mayo Clinic diagnosed with multiple myeloma, she believed the time she had left to live was limited. But to her surprise, the individualized treatment she received put her cancer in remission. When Diane Thompson was diagnosed with multiple myeloma in December 2014, she was given two years to live. At [...]

    6. Finding Blessings in My Battle With Leukemia

      Janie Magruder reflects on her cancer diagnosis and treatment, including a crucial stem cell donation from an unlikely source that helped to save her life. Written by Janie Magruder I must have looked like a deer caught in the headlights. "You're going to be fine," whispered my nurse after getting me settled in my hospital [...]

    Expertise and rankings

    Image of Mayo Clinic specialist working together Experience you can count on

    Mayo Clinic specialists work together, combining their knowledge and experience in caring for to people undergoing bone marrow transplant to provide the most effective care. This experience and expertise earns Mayo Clinic doctors respect from colleagues around the world.

    Each year, Mayo Clinic doctors diagnose and treat thousands of people who have blood or bone marrow disease, many of whom benefit from bone marrow transplant. Mayo Clinic's Bone Marrow Transplant Program is among the largest in the country.

    Mayo Clinic is recognized for excellence in bone marrow transplant by national and international groups:

    Learn more about Mayo Clinic's quality rankings.

    Volumes and outcomes

     

    Mayo Clinic doctors' experience and integrated team approach results in transplant outcomes that compare favorably with national averages. Teams work with transplant recipients before, during and after surgery to ensure the greatest likelihood of superior results.

    Volumes and outcomes are maintained separately for the three Mayo Clinic locations. Taken together or separately, transplant recipients at Mayo Clinic enjoy excellent results.

    Locations, travel and lodging

    The Village at Mayo Clinic in Phoenix, Arizona, offers low-cost housing for transplant patients and their caregivers.

    The Gabriel House of Care in Jacksonville, Florida, offers low-cost housing for transplant patients and their caregivers.

    The Gift of Life Transplant House in Rochester, Minnesota, offers low-cost housing for transplant patients and their caregivers.

    Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

    For more information on visiting Mayo Clinic, choose your location below:

    Costs and insurance

    Bone marrow transplant costs and insurance information

    Mayo Clinic has dedicated transplant financial services representatives and social workers who can assist you with insurance and financial questions regarding your transplant.

    Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people. In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. Many insurance companies require you to get preapproval authorization prior to transplant services.

    Insurance information

    Before your transplant, it's important that you work closely with your insurance company to understand your benefit plan. You'll be responsible for any of your transplant and medical care costs not covered by your insurance company.

    You may want to ask your insurance company several questions regarding your transplant expenses, including:

    • What is the specific coverage of my plan? What are my deductibles, coinsurance, copayments, lifetime maximum amount and annual maximum amounts for both medical care and transplant services?
    • Does my plan have a pre-existing or waiting period clause? If so, what is the time frame? Can this be waived?
    • Does my plan include pharmacy coverage? If so, will my plan cover my current medications and immunosuppressant medications?
    • Does my plan require any special approvals for evaluation or transplant? How long does the approval process take once submitted to insurance?
    • Does my plan cover my transportation and lodging expenses during my transplant care?
    • Does my current insurance require enrollment in Medicare when eligible?
    • Does my insurance follow Medicare Coordination of Benefits guidelines?
    • How will my current coverage change after enrolling in Medicare? Will my plan become a supplemental or secondary plan?

    If your plan is a Medicare supplement, ask questions including:

    • Does my plan follow Medicare guidelines?
    • Does my plan cover Medicare Part A and B deductible and coinsurance?
    • Does my plan have a pre-existing or waiting period? If so, what is the time frame?
    • Does my plan offer an option for Medicare Part D coverage?

    Other expenses

    Please plan for other expenses that may occur related to your transplant, which may include follow-up medical appointments, long-term medications, caregiver expenses, travel, parking, lodging and other expenses.

    If you have an allogeneic bone marrow transplant, your donor's transplant-related medical care may be paid by your insurance company.

    For international patients

    Mayo Clinic has dedicated international patient account representatives who can assist you with questions regarding your costs and insurance. Read more about international financial services.

    Case managers

    Mayo Clinic financial staff will work closely with your case managers from your insurance company. Your case manager, who is assigned to you, is available to answer questions and calls related to your insurance costs.

    More information about billing and insurance:

    Mayo Clinic in Arizona, Florida and Minnesota

    Mayo Clinic Health System

    Clinical trials

    Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this disease.

    July 11, 2019
    References
    1. AskMayoExpert. Hematopoietic stem cell transplant. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2015.
    2. Hoffman R, et al. Overview of hematopoietic stem cell transplantation. In: Hematology: Basic Principles and Practice. 6th ed. Philadelphia, Pa.: Saunders Elsevier; 2013. http://www.clinicalkey.com. Accessed July 8, 2016.
    3. Blood-forming stem cell transplants. National Cancer Institute. http://www.cancer.gov/about-cancer/treatment/types/stem-cell-transplant/stem-cell-fact-sheet. Accessed July 8, 2016.
    4. Majhail NS, et al. Recommended screening and preventive practices for long-term survivors after hematopoietic cell transplantation. Biology of Blood and Marrow Transplantation. 2012;18:348.
    5. Diseases treatable by transplants. National Marrow Donor Program. https://bethematch.org/transplant-basics/how-transplants-work/diseases-treatable-by-transplants/. Accessed July 8, 2016.
    6. AskMayoExpert. Graft-versus-host disease. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014.
    7. Blood and marrow stem cell transplantation. Leukemia & Lymphoma Society. http://www.lls.org/resource-center/download-or-order-free-publications. Accessed July 8, 2016.
    8. Barbara Woodward Lips Patient Education Center. Autologous stem cell transplant. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014.
    9. Riggin EA. Allscripts EPSi. Mayo Clinic, Rochester, Minn. July 20, 2016.