There is no solid evidence that cortisol blockers lead to weight loss.
Manufacturers of cortisol blockers claim that high stress levels increase your body's production of the hormone cortisol, which increases appetite and leads to weight gain.
However, the connection between stress hormones and weight gain is largely based on anecdotal evidence, with only a few studies supporting it. The role of hormones on weight gain remains unclear.
As for evidence that cortisol blockers cause weight loss, the Federal Trade Commission charged the marketers of some cortisol blockers with making false and unsubstantiated claims about their products' effectiveness. As a result, the companies had to pay millions of dollars in refunds and stop making unproven claims about their products.
Bottom line: Steer clear of weight-loss products that make unproven claims. Instead, focus on reducing your calorie intake and increasing your activity level. For lowering stress, explore stress management techniques.
April 24, 2018
See more Expert Answers
- CortiSlim by Window Rock Health Laboratories. Natural Medicines. https://naturalmedicines.therapeuticresearch.com. Accessed March 26, 2018.
- Stress management and CortiSlim — How to de-stress. CortiSlim. http://www.cortislim.com/stress-cortislim-s/1816.htm. Accessed March 23, 2018.
- Perreault L. Obesity in adults: Drug therapy. https://www.uptodate.com/contents/search. Accessed March 26, 2018.
- Federal Trade Commission reaches New Years resolutions with four major weight-control pill marketers. Federal Trade Commission. https://www.ftc.gov/news-events/press-releases/2007/01/federal-trade-commission-reaches-new-years-resolutions-four-major. Accessed March 26, 2018.
- Leow S, et al. A role for exercise in attenuating unhealthy food consumption in response to stress. Nutrients. 2018;10:176.
- Junne F, et al. Determinants of perceived stress in individuals with obesity: Exploring the relationship of potentially obesity-related factors and perceived stress. Obesity Facts. 2017;10:127.
- Schwartz MW, et al. Obesity pathogenesis: An Endocrine Society scientific statement. Endocrine Reviews. 2017;38:267.