Primary biliary cholangitis (PBC)

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Doctors who treat this condition

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Displaying 1-10 out of 19 doctors available

  1. Michele Barnhill, M.D.

    Michele Barnhill, M.D.

    1. Gastroenterologist
    2. Transplant Hepatologist
    1. Phoenix, AZ
    Areas of focus:

    Colonoscopy, Esophagoscopy, Variceal band ligation, Hepatic encephalopathy, Cirrhosis, Nonalcoholic fatty liver disease..., Primary biliary cholangitis, Primary sclerosing cholangitis, Portal hypertension, Autoimmune hepatitis, Hemochromatosis, Alcoholic hepatitis, Biliary atresia

  2. Elizabeth J. Carey, M.D.

    Elizabeth J. Carey, M.D.

    1. Internist
    2. Gastroenterologist
    3. Transplant Hepatologist
    1. Phoenix, AZ
    Areas of focus:

    Liver transplant, Hepatic encephalopathy, Cirrhosis, Nonalcoholic fatty liver disease, Primary biliary cholangitis, Pri...mary sclerosing cholangitis, Autoimmune hepatitis, Alcoholic hepatitis

  3. Alex Cortez, M.D.

    Alex Cortez, M.D.

    1. Transplant Surgeon
    1. Rochester, MN
    Areas of focus:

    Liver transplant, Kidney transplant, Hernia repair, Cholecystectomy, Robotic surgery, Liver resection, Liver cyst fenes...tration, Liver cancer, Hepatocellular carcinoma, Cirrhosis, Alcoholic liver disease, Chronic liver disease, Primary biliary cholangitis, Cholangiocarcinoma, Primary sclerosing cholangitis, Portal hypertension, Acute liver failure, Autoimmune hepatitis, Polycystic liver disease, Polycystic kidney disease, End-stage renal disease, Budd-Chiari syndrome, Metabolic liver disease

  4. Denise M. Harnois, D.O.

    Denise M. Harnois, D.O.

    1. Transplant Hepatologist
    1. Jacksonville, FL
    Areas of focus:

    Liver transplant, Post-transplant long-term care, Pre-transplant evaluation, Hepatic encephalopathy, Liver cancer, Hepa...tocellular carcinoma, Cirrhosis, Nonalcoholic fatty liver disease, Primary biliary cholangitis, Cholangiocarcinoma, Primary sclerosing cholangitis, Liver disease, Alcoholic hepatitis, Hepatopulmonary syndrome

  5. Sumera I. Ilyas, M.B.B.S.

    Sumera I. Ilyas, M.B.B.S.

    1. Transplant Hepatologist
    1. Rochester, MN
    Areas of focus:

    Hepatocellular carcinoma, Cirrhosis, Hepatitis C, Hepatitis B, Neuroendocrine tumor, Nonalcoholic fatty liver disease, ...Chronic liver disease, Primary biliary cholangitis, Intrahepatic cholangiocarcinoma, Cholangiocarcinoma, Primary sclerosing cholangitis, Perihilar cholangiocarcinoma, Autoimmune hepatitis, Hemochromatosis, Alcoholic hepatitis, Stage 4 colorectal cancer, Liver hemangioendothelioma, Liver adenomatosis

  6. Channa R. Jayasekera, M.D.

    Channa R. Jayasekera, M.D.

    1. Gastroenterologist
    2. Transplant Hepatologist
    1. Phoenix, AZ
    Areas of focus:

    Liver transplant, Upper endoscopy, Colonoscopy, Jaundice, Hepatic encephalopathy, Liver cancer, Hepatocellular carcinom...a, Cirrhosis, Alcoholic liver disease, Hepatitis C, Hepatitis B, Nonalcoholic fatty liver disease, Primary biliary cholangitis, Liver tumor, Cholangiocarcinoma, Primary sclerosing cholangitis, Liver injury, Liver mass, Portal hypertension, Liver disease, Hemochromatosis, Alcoholic hepatitis, Metabolic liver disease

  7. Andrew P. Keaveny, M.D.

    Andrew P. Keaveny, M.D.

    1. Transplant Hepatologist
    1. Jacksonville, FL
    Areas of focus:

    Liver transplant, Living donor liver transplant, Post-transplant long-term care, Pre-transplant evaluation, Hepatic enc...ephalopathy, Liver cancer, Hepatocellular carcinoma, Cirrhosis, Nonalcoholic fatty liver disease, Primary biliary cholangitis, Cholangiocarcinoma, Primary sclerosing cholangitis, Portal hypertension, Acute liver failure, Liver disease, Alcoholic hepatitis, Hepatopulmonary syndrome

  8. Konstantinos N. Lazaridis, M.D.

    Konstantinos N. Lazaridis, M.D.

    1. Gastroenterologist
    1. Rochester, MN
    Areas of focus:

    Liver cancer, Primary biliary cholangitis, Primary sclerosing cholangitis

  9. Michael D. Leise, M.D.

    Michael D. Leise, M.D.

    1. Transplant Hepatologist
    1. Rochester, MN
    Areas of focus:

    Upper endoscopy, Colonoscopy, Hepatic encephalopathy, Hepatocellular carcinoma, Cirrhosis, Hepatitis C, Hepatitis B, No...nalcoholic fatty liver disease, Primary biliary cholangitis, Cholangiocarcinoma, Primary sclerosing cholangitis, Wilson's disease, Portal hypertension, Liver disease, Autoimmune hepatitis, Hereditary hemorrhagic telangiectasia, Hemochromatosis, Alcoholic hepatitis, Hepatopulmonary syndrome, Esophageal varices, Portopulmonary hypertension

  10. Nicole M. Loo, M.D.

    Nicole M. Loo, M.D.

    1. Internist
    2. Transplant Hepatologist
    1. Jacksonville, FL
    Areas of focus:

    Liver transplant, Post-transplant long-term care, Pre-transplant evaluation, Hepatic encephalopathy, Liver cancer, Hepa...tocellular carcinoma, Cirrhosis, Hepatitis C, Hepatitis B, Nonalcoholic fatty liver disease, Primary biliary cholangitis, Cholangiocarcinoma, Primary sclerosing cholangitis, Liver mass, Acute liver failure, Liver disease, Autoimmune hepatitis, Alcoholic hepatitis, Hepatopulmonary syndrome, Fatty liver disease

Research

Mayo Clinic has been conducting research on primary biliary cholangitis for more than 50 years. Many treatments for the disease have been studied at Mayo Clinic. Mayo Clinic was one of the first centers to study ursodiol as a treatment option. Researchers are currently studying new medicines and combinations of therapies for people with only a partial response to ursodiol.

Researchers at Mayo Clinic have made many contributions to understanding the genetics of primary biliary cholangitis (PBC). They've helped find several gene variations that seem to make people more likely to develop the disease. Their discoveries are the first step toward developing targeted treatments and potentially curing the disease.

Also, researchers at Mayo Clinic have found that first-degree relatives — parents, siblings or children — of people with the disease are more likely to carry an antibody related to PBC. The finding suggests that a simple blood test may help healthcare professionals monitor people for early signs of PBC.

Basic research related to PBC and other liver diseases is conducted in the following Mayo Clinic laboratories:

Publications

See a list of publications about primary biliary cholangitis by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

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By Mayo Clinic Staff

Primary biliary cholangitis (PBC) care at Mayo Clinic

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Diagnosis & treatmentCare at Mayo Clinic
Feb. 27, 2026
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Primary biliary cholangitis (PBC)

Research: It's all about patients

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Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight.