Primary biliary cholangitis

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Doctors who treat this condition

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Displaying 1-10 out of 18 doctors available

  1. Michele Barnhill, M.D.

    Michele Barnhill, M.D.

    1. Gastroenterologist
    2. Transplant Hepatologist
    1. Phoenix, AZ
    Areas of focus:

    Colonoscopy, Esophagoscopy, Variceal band ligation, Primary sclerosing cholangitis, Primary biliary cholangitis, Nonalc...oholic fatty liver disease, Cirrhosis, Autoimmune hepatitis, Alcoholic hepatitis, Hemochromatosis, Hepatic encephalopathy, Portal hypertension, Biliary atresia

  2. Elizabeth J. Carey, M.D.

    Elizabeth J. Carey, M.D.

    1. Internist
    2. Gastroenterologist
    3. Transplant Hepatologist
    1. Phoenix, AZ
    Areas of focus:

    Liver transplant, Primary sclerosing cholangitis, Primary biliary cholangitis, Nonalcoholic fatty liver disease, Cirrho...sis, Autoimmune hepatitis, Alcoholic hepatitis, Hepatic encephalopathy

  3. Alex Cortez, M.D.

    Alex Cortez, M.D.

    1. Transplant Surgeon
    1. Rochester, MN
    Areas of focus:

    Liver transplant, Kidney transplant, Cholecystectomy, Liver resection, Hernia repair, Liver cyst fenestration, Cholangi...ocarcinoma, Primary sclerosing cholangitis, Polycystic kidney disease, Hepatocellular carcinoma, Primary biliary cholangitis, Cirrhosis, Acute liver failure, Autoimmune hepatitis, Liver cancer, End-stage renal disease, Alcoholic liver disease, Portal hypertension, Chronic liver disease, Budd-Chiari syndrome, Metabolic liver disease, Polycystic liver disease

  4. Denise M. Harnois, D.O.

    Denise M. Harnois, D.O.

    1. Transplant Hepatologist
    1. Jacksonville, FL
    Areas of focus:

    Liver transplant, Pre-transplant evaluation, Post-transplant long-term care, Cholangiocarcinoma, Primary sclerosing cho...langitis, Hepatocellular carcinoma, Primary biliary cholangitis, Nonalcoholic fatty liver disease, Cirrhosis, Alcoholic hepatitis, Hepatopulmonary syndrome, Liver disease, Liver cancer, Hepatic encephalopathy

  5. Sumera I. Ilyas, M.B.B.S.

    Sumera I. Ilyas, M.B.B.S.

    1. Transplant Hepatologist
    1. Rochester, MN
    Areas of focus:

    Cholangiocarcinoma, Primary sclerosing cholangitis, Hepatitis C, Hepatitis B, Hepatocellular carcinoma, Primary biliary... cholangitis, Nonalcoholic fatty liver disease, Cirrhosis, Autoimmune hepatitis, Alcoholic hepatitis, Hemochromatosis, Neuroendocrine tumor, Stage 4 colorectal cancer, Chronic liver disease, Intrahepatic cholangiocarcinoma, Liver hemangioendothelioma, Liver adenomatosis, Perihilar cholangiocarcinoma

  6. Channa R. Jayasekera, M.D.

    Channa R. Jayasekera, M.D.

    1. Gastroenterologist
    2. Transplant Hepatologist
    1. Phoenix, AZ
    Areas of focus:

    Liver transplant, Primary sclerosing cholangitis, Hepatitis C, Hepatitis B, Hepatocellular carcinoma, Primary biliary c...holangitis, Nonalcoholic fatty liver disease, Cirrhosis, Jaundice, Alcoholic hepatitis, Hemochromatosis, Liver disease, Liver cancer, Alcoholic liver disease, Hepatic encephalopathy, Portal hypertension, Liver tumor, Metabolic liver disease, Liver mass, Liver injury

  7. Andrew P. Keaveny, M.D.

    Andrew P. Keaveny, M.D.

    1. Transplant Hepatologist
    1. Jacksonville, FL
    Areas of focus:

    Liver transplant, Living donor liver transplant, Pre-transplant evaluation, Post-transplant long-term care, Cholangioca...rcinoma, Primary sclerosing cholangitis, Hepatocellular carcinoma, Primary biliary cholangitis, Nonalcoholic fatty liver disease, Cirrhosis, Acute liver failure, Alcoholic hepatitis, Hepatopulmonary syndrome, Liver disease, Liver cancer, Hepatic encephalopathy, Portal hypertension

  8. Konstantinos N. Lazaridis, M.D.

    Konstantinos N. Lazaridis, M.D.

    1. Gastroenterologist
    1. Rochester, MN
    Areas of focus:

    Primary sclerosing cholangitis, Primary biliary cholangitis, Liver cancer

  9. Michael D. Leise, M.D.

    Michael D. Leise, M.D.

    1. Transplant Hepatologist
    1. Rochester, MN
    Areas of focus:

    Colonoscopy, Upper endoscopy, Cholangiocarcinoma, Primary sclerosing cholangitis, Hereditary hemorrhagic telangiectasia..., Hepatitis C, Wilson's disease, Hepatitis B, Hepatocellular carcinoma, Primary biliary cholangitis, Nonalcoholic fatty liver disease, Cirrhosis, Autoimmune hepatitis, Alcoholic hepatitis, Hepatopulmonary syndrome, Hemochromatosis, Liver disease, Esophageal varices, Hepatic encephalopathy, Portal hypertension, Portopulmonary hypertension

  10. Nicole M. Loo, M.D.

    Nicole M. Loo, M.D.

    1. Internist
    2. Transplant Hepatologist
    1. Jacksonville, FL
    Areas of focus:

    Liver transplant, Pre-transplant evaluation, Post-transplant long-term care, Cholangiocarcinoma, Primary sclerosing cho...langitis, Hepatitis C, Hepatitis B, Hepatocellular carcinoma, Primary biliary cholangitis, Nonalcoholic fatty liver disease, Cirrhosis, Acute liver failure, Autoimmune hepatitis, Alcoholic hepatitis, Hepatopulmonary syndrome, Liver disease, Liver cancer, Hepatic encephalopathy, Fatty liver disease, Liver mass

Research

Mayo Clinic has been conducting research on primary biliary cholangitis for more than 40 years, and many treatments for the disease have been studied at Mayo Clinic. Mayo Clinic was one of the first centers to study ursodeoxycholic acid (UDCA) as a treatment option. Researchers are currently studying new medications — including applying a combination of therapies — for people with only a partial response to UDCA.

The Mayo Clinic research team has made many contributions to understanding the genetics of primary biliary cholangitis. They've helped find several gene variations that seem to make people more likely to develop the disease. Their discoveries are the first step toward developing targeted treatments and potentially curing the disease.

Also, researchers at Mayo Clinic have found that first-degree relatives — parents, siblings or children — of people with primary biliary cholangitis are more likely to have a protein in their blood that indicates the presence of the disease. Doctors call this a biomarker. The finding suggests that a simple blood test could help doctors detect the disease early in first-degree relatives so that treatment can begin before it causes irreversible liver damage.

Basic research related to primary biliary cholangitis and other liver diseases is conducted in the following Mayo Clinic laboratories:

Publications

See a list of publications about primary biliary cholangitis by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

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By Mayo Clinic Staff

Primary biliary cholangitis care at Mayo Clinic

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Diagnosis & treatmentCare at Mayo Clinic
Sept. 16, 2025
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Primary biliary cholangitis

Research: It's all about patients

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Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight.