Diagnosis

Early diagnosis of myocarditis is important to preventing long-term heart damage. To diagnose myocarditis, a health care provider will typically examine you and listen to your heart with a stethoscope.

Blood and imaging tests may be done to check your heart health. Imaging tests can help confirm myocarditis and determine its severity.

Tests to diagnose myocarditis include:

  • Blood tests. Blood tests are usually done to check for signs of a heart attack, inflammation and infection. A cardiac enzyme test can check for proteins related to heart muscle damage. Antibody blood tests may help determine if you had an infection linked to myocarditis.
  • Electrocardiogram (ECG or EKG). This quick and painless test shows how the heart is beating. Your health care provider can look for signal patterns on an ECG to determine if you have irregular heartbeats (arrhythmias). Some personal devices, such as smartwatches, offer electrocardiogram monitoring. Ask your health care provider if this is an option for you.
  • Chest X-ray. A chest X-ray shows the size and shape of the heart and lungs. A chest X-ray can tell if there's fluid in or around the heart that might be related to heart failure.
  • Heart MRI (Cardiac MRI). This test uses magnetic fields and radio waves to create detailed images of the heart. A cardiac MRI shows the heart's size, shape and structure. It can show signs of heart muscle inflammation.
  • Echocardiogram. Sound waves create moving images of the beating heart. An echocardiogram can show the heart's size and how well blood flows through the heart and heart valves. An echocardiogram can help determine if there's fluid around the heart.
  • Cardiac catheterization and heart muscle biopsy. A health care provider threads a thin tube (catheter) through a blood vessel in the arm or groin to an artery in the heart. Dye flows through the catheter to help the heart (coronary) arteries show up more clearly on X-rays. A tiny sample of heart muscle tissue (biopsy) may be taken during this test. The sample is sent to a lab to be checked for inflammation or infection.

Treatment

Often, myocarditis improves on its own or with treatment. Myocarditis treatment focuses on the cause and the symptoms, such as heart failure.

Medications

People with mild myocarditis may only need rest and medication. Medications to treat myocarditis may include:

  • Corticosteroids. These medicines suppress the immune system. They may be used to treat some rare types of viral myocarditis, such as giant cell and eosinophilic myocarditis.
  • Heart medications. If myocarditis is causing severe heart failure or irregular heartbeats, drugs may be given to reduce the risk of blood clots in the heart.

    For a weak heart, medications can help remove extra fluid from the body and reduce the strain on the heart. Some types of medications that may be given are diuretics, beta blockers, angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers (ARBs).

  • Medications to treat chronic conditions. Sometimes another health condition, such as lupus, causes myocarditis. Treating the underlying condition may help reduce heart muscle inflammation.

Some people with myocarditis may need medications for just a few months and then recover completely. Others may have long-term, permanent heart damage that needs lifelong medication. It's important to have regular health checkups after a diagnosis of myocarditis to check for possible complications.

Surgeries and procedures

If you have severe myocarditis, you will need aggressive treatment, which might include:

  • IV medications. Medications given through an IV are used to quickly improve the heart's ability to pump.
  • Ventricular assist device (VAD). A VAD helps pump blood from the lower chambers of the heart (the ventricles) to the rest of the body. It's a treatment for a weakened heart or heart failure. A VAD may be used to help the heart work while waiting for other treatments, such as a heart transplant.
  • Intra-aortic balloon pump. This device helps increase blood flow and lower the strain on the heart. The heart doctor (cardiologist) inserts a thin tube (catheter) into a blood vessel in the leg and guides it to the heart. A balloon attached to the end of the catheter inflates and deflates in the main artery leading out to the body from the heart (aorta).
  • Extracorporeal membrane oxygenation (ECMO). An ECMO machine works like the lungs.It removes carbon dioxide and adds oxygen to the blood. If you have severe heart failure, this device can send oxygen to your body. During ECMO, blood is removed from the body, passed through the machine and then returned to the body.

    ECMO may be used to help the heart to recover or while waiting for other treatments, such as a heart transplant.

  • Heart transplant. An urgent heart transplant may be needed for those who have very severe myocarditis.

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Lifestyle and home remedies

Rest and reducing the strain on the heart is an important part of myocarditis recovery. If you have or had myocarditis, ask your health care provider which type and amount of physical activity is safe for you.

If you have myocarditis, you should avoid competitive sports for at least 3 to 6 months.

Following a healthy lifestyle is an important part of myocarditis treatment and recovery. Try these heart-healthy strategies:

  • Limit salt.
  • Avoid or limit alcohol.
  • Don't smoke.

Some people may need to restrict fluids. Ask your care provider what your fluid intake should be.

Preparing for your appointment

If you have mild myocarditis symptoms, you may start with your primary care provider. If symptoms are severe, you may first be seen by an emergency room care provider. You'll likely be referred to a doctor trained in heart conditions (cardiologist) and possibly a doctor trained in infectious disease.

What you can do

Here's some information to help you get ready for your appointment. Write down the following details:

  • Your symptoms, including any that might seem unrelated to myocarditis, and when they began
  • Important personal information, including recent illnesses and the symptoms, recent travel locations, and your and your family's medical history
  • All medications, vitamins or other supplements you take, including doses
  • Questions to ask your health care provider

For myocarditis, basic questions to ask your care provider include:

  • What's the most likely cause of my symptoms?
  • What are other possible causes?
  • What tests do I need?
  • How is myocarditis treated?
  • What side effects can I expect from treatment?
  • Are there alternatives to the primary approach you're suggesting?
  • I have other health conditions. How can I best manage these conditions together?
  • Do I need to restrict my activities or diet?
  • Are there brochures or other printed material I can have? What websites do you recommend?

Don't hesitate to ask other questions. Take a family member or friend along to your appointment, if possible, to help you remember the information you'll receive.

What to expect from your doctor

Your care provider is likely to ask many questions, including:

  • Have you recently been sick or have you recovered from another illness?
  • Have you traveled out of the country recently?
  • What, if anything, makes symptoms better?
  • What, if anything, makes your symptoms worse?

Myocarditis care at Mayo Clinic

May 20, 2022
  1. AskMayoExpert. Myocarditis. Mayo Clinic; 2021.
  2. Cooper LT. Clinical manifestations and diagnosis of myocarditis in adults. https://www.uptodate.com/contents/search. Accessed March 23, 2022.
  3. Ammirati E, et al. Management of acute myocarditis and chronic inflammatory cardiomyopathy. Circulation. 2020; doi:10.1161/CIRCHEARTFAILURE.120.007405.
  4. Cooper LT. Myocarditis: Causes and pathogenesis. https://www.uptodate.com/contents/search. Accessed March 23, 2022.
  5. Siripanthong B, et al. Recognizing COVID-19–related myocarditis: The possible pathophysiology and proposed guideline for diagnosis and management. Heart Rhythm. 2020; doi:10.1016/j.hrthm.2020.05.001.
  6. Ferri FF. Myocarditis. In: Ferri's Clinical Advisor 2021. Elsevier; 2021. https://www.clinicalkey.com. Accessed March 23, 2022.
  7. Cooper LT. Treatment and prognosis of myocarditis in adults. https://www.uptodate.com/contents/search. Accessed March 23, 2022.
  8. Allan CK, et al. Clinical manifestations and diagnosis of myocarditis in children. https://www.uptodate.com/contents/search. Accessed March 23, 2022.
  9. Bonow RO, et al., eds. Myocarditis. In: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 11th ed. Elsevier; 2019. https://www.clinicalkey.com. Accessed March 23, 2022.
  10. Nguyen LS, et al. Systematic analysis of drug-associated myocarditis reported in the World Health Organization pharmacovigilance database. Nature Communications. 2022; doi:10.1038/s41467-021-27631-8.
  11. Healthy habits to help prevent flu. Centers for Disease Control and Prevention. https://www.cdc.gov/flu/prevent/actions-prevent-flu.htm. Accessed March 23, 2022.
  12. Cooper LT, et al. The role of endomyocardial biopsy in the management of cardiovascular disease: A scientific statement from the American Heart Association, the American College of Cardiology, and the European Society of Cardiology. Circulation. 2007;116:2216.
  13. Braswell-Pickering EA. Allscripts EPSi. Mayo Clinic. Feb. 28, 2022.
  14. Mankad R (expert opinion). Mayo Clinic. April 13, 2022.
  15. Cheng CY, et al. Myocarditis in systemic immune-mediated diseases: Prevalence, characteristics and prognosis. A systematic review. Autoimmunity Reviews. 2022; doi:10.1016/j.autrev.2022.103037.
  16. Lopez-Jimenez F (expert opinion). Mayo Clinic. Nov. 29, 2021.
  17. Myocarditis and pericarditis after mRNA COVID-19 vaccination. Centers for Disease Control and Prevention. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/myocarditis.html. Accessed April 13, 2022.
  18. Hause AM, et al. Safety monitoring of COVID-19 vaccine booster doses among persons aged 12–17 years — United States, December 9, 2021-February 20, 2022. MMWR Morbidity and Mortality Weekly Report. 2022; doi: 10.15585/mmwr.mm7109e2.
  19. Mouch SA, et al. Myocarditis following COVID-19 mRNA vaccination. Vaccine. 2021; doi:10.1016/j.vaccine.2021.05.087.
  20. Mevorach D, et al. Myocarditis after BNT162b2 mRNA vaccine against Covid-19 in Israel. The New England Journal of Medicine. 2021; doi:10.1056/NEJMoa2109730.
  21. Lee ASY, et al. Myocarditis following COVID-19 vaccination: A systematic review (October 2020-October 2021). Heart, Lung and Circulation. 2022; doi:10.1016/j.hlc.2022.02.002.
  22. COVID-19: Get the facts. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-vaccine/art-20484859. Accessed April 14, 2022.