A researcher fills test tubes in a lab dedicated to improving fetal and maternal health.

Mayo Clinic clinician-researchers and scientists are committed to conducting research to improve diagnosis and prevention and develop new treatment options. They are nationally and internationally recognized for contributions to advancing the frontier of reproductive medicine. Mayo Clinic also leads several projects funded by the National Institutes of Health.

Areas of particular interest include:

  • Promoting fetal survival and lung development
  • Evaluating new technologies and assessing their application to clinical practice
  • Improving the diagnosis and expanding treatment options of benign gynecologic disorders
  • Studying innovative treatment options for minimally invasive surgery
  • Studying what causes pregnancy complications and lowering the risk of complications
  • Collaborating with clinical genomics in research of common chromosomal and genetic diseases in pregnancy
  • Investigating the safety of offering cancer-reducing surgery to women delivering by cesarean section
  • Using regenerative products to provide new options for women with mesh exposure after pelvic reconstructive surgery
  • Using epidemiology studies, clinical trials and patient-centered outcomes to improve the ergonomics and materials used in treating pelvic floor disorders

In addition, Mayo Clinic is one of only five institutions in the United States to be awarded an ovarian cancer Specialized Program of Research Excellence (SPORE) grant from the National Institutes of Health (NIH). Read more about gynecologic oncology research in the Mayo Clinic Cancer Center.

Research labs

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Research centers and programs


See a list of publications by Mayo Clinic authors on gynecologic surgery and obstetrics on PubMed, a service of the National Library of Medicine.

Clinical trials

Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage conditions of the female urinary and reproductive systems. For general information about clinical trials in obstetrics and gynecology in Minnesota, call 507-293-1487. For information about cancer-related clinical trials in Minnesota, call 507-538-7623. In Florida, call 904-953-2978. In Arizona, call 855-776-0015.

Research Profiles

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May 07, 2021
  1. Congenital anomalies. World Health Organization. Accessed Feb. 8, 2018.
  2. Birth defects. Centers for Disease Control and Prevention. Accessed Feb. 8, 2018.
  3. Srinivasan S, et al. Overview of fetal arrhythmias. Current Opinion in Pediatrics. 2008;20:522.
  4. Brennand J, et al. Fetal anaemia: Diagnosis and management. Best Practice & Research Clinical Obstetrics and Gynaecology. 2008;22:15.
  5. Kalyani R, et al. Twin reversed arterial perfusion syndrome (TRAP or acardiac twin): A case report. Journal of Clinical and Diagnostic Research. 2014;8:166.
  6. Djaafri F, et al. Twin-twin transfusion syndrome: What we have learned from clinical trials. Seminars in Fetal and Neonatal Medicine. 2017;22:367.
  7. D'Antonio F, et al. Prenatal risk factors and outcomes in gastroschisis: A meta-analysis. Pediatrics. 2015;136:e159. Accessed Feb. 8, 2018.
  8. Alpha-fetoprotein (AFP), single marker screen, maternal, serum. Mayo Medical Laboratories. Accessed Feb. 8, 2018.
  9. AskMayoExpert. Prenatal screening and testing. Mayo Clinic; 2019.
  10. Screening for fetal anomalies. National Institutes of Health. Accessed Feb. 9, 2018.
  11. Baer RJ, et al. 311: Risk of preterm birth by subtype of infants with gastroschisis. American Journal of Obstetrics and Gynecology. 2017;216(suppl):S190.
  12. Wyllie R, et al., eds. Abnormal rotation and fixation of the intestine. In: Pediatric Gastrointestinal and Liver disease. 5th ed. Philadelphia, Pa.: Elsevier; 2016. Accessed Feb. 12, 2018.
  13. Lee H, et al. Efficacy of radiofrequency ablation for twin-reversed arterial perfusion sequence. American Journal of Obstetrics and Gynecology. 2007;196:e1.
  14. Wee LY, et al. The twin-twin transfusion syndrome. Seminars in Neonatology. 2002;7:187.
  15. Enninga EA (expert opinion). Mayo Clinic. Feb. 13, 2018.
  16. Famuyide AO (expert opinion). Mayo Clinic. March 1, 2018.
  17. Magtibay PM (expert opinion). Mayo Clinic. March 1, 2018.
  18. Amanda Ullom. Mayo Scheduling System. Mayo Clinic. Feb. 27, 2018.
  19. Occhino J (expert opinion). Mayo Clinic. Feb. 10, 2020.
  20. Rassier SL (expert opinion). Mayo Clinic. Feb. 19, 2021.