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Obstetrics and Gynecology

Clinical trials

Below are current clinical trials.


43 studies in Obstetrics and Gynecology
(open studies only).

Filter this list of studies by location, status and more.

  1. Sequencing for Families with Hereditary Disorders

    Rochester, Minn.

    The purpose of this project will examine the feasibility of offering whole genome sequencing (WGS), and developing a Rapid WGS protocol, for a fetus or neonate with multiple anomalies.

  2. A Study to Evaluate Women's Birth Experience and Postpartum Mental Health Outcomes

    Rochester, Minn.

    The purpose of this study is to implement a facilitated peer support group for women that have experienced an unexpected birth process in the last 12 months. 

  3. OTL38 for Intra-operative Imaging of Folate Receptor Positive Ovarian Cancer

    Rochester, Minn., Scottsdale/Phoenix, Ariz.

    This is a phase 3, randomized, multi-center, single dose, open label, pivotal study in patients diagnosed with, or with high clinical suspicion of, ovarian cancer scheduled to undergo primary surgical cytoreduction, interval debulking, or recurrent ovarian cancer surgery.

  4. A Study to Learn More About the Relationship between Fetal DNA and the Maternal Immune System

    Rochester, Minn.

    The purpose of this study is to learn about the ability of fetal DNA to activate the immune system.

  5. A Study to Evaluate Minimally Invasive Fetoscopic Regenerative Repair of Spina Bifida

    Rochester, Minn.

    The purpose of this study is to evaluate a new, minimally-invasive technique (fetoscopic repair) for repair of spina bifida (MMC) during the second trimester of pregnancy. Researchers are trying to determine if this less invasive surgical approach will have less risk to the mother and, at the same time, adequate closure of the fetal spina bifida defect.

  6. A Study to Investigate FE 999049 in the Treatment of Infertility in Women Aged 18-34 Years Old with Assisted Reproductive Technology

    Rochester, Minn.

    The purpose of this study is to investigate the safety and effectiveness of FE 999049 compared to placebo in women aged 18-34 years old.

  7. A Study of Automated Myocardial Performance Index Before, During and After Fetal Surgeries using Samsung HERA W10

    Rochester, Minn.

    The purpose of this study is to evaluate the cardiac function in fetuses with specific conditions before, during, and after fetal interventions using an automated myocardial performance index.

  8. A Study of Ovarian Tissue Freezing for the Preservation of Fertility in Children

    Rochester, Minn.

    The purpose of this study is to offer ovarian tissue cryopreservation to female pediatric patients (birth-17 years of age) with fertility threatening medical diagnoses or facing surgery, chemotherapy or radiation therapy that may cause loss of reproductive potential. Since this procedure is currently considered experimental, the establishment of an IRB protocol under which this opportunity can be offered is needed.

  9. Changes in Systemic Immunity in Patients with Ovarian Cancer

    Rochester, Minn.

    The purpose of this study is to understand changes that take place over time in the immune system in patients with ovarian cancer, fallopian tube cancer, and primary peritoneal cancer.

  10. Study for Patient-Directed Postoperative Opioid Prescribing for Gynecologic Surgery

    Scottsdale/Phoenix, Ariz.

    The purpose of this study is to evaluate the impact of patient input on opioid prescribing and overall opioid use following gynecologic surgery.

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Locations, travel & lodgingResearch
Nov. 19, 2019
  1. Congenital anomalies. World Health Organization. http://www.who.int/mediacentre/factsheets/fs370/en/. Accessed Feb. 8, 2018.
  2. Birth defects. Centers for Disease Control and Prevention. https://www.cdc.gov/ncbddd/birthdefects/data.html. Accessed Feb. 8, 2018.
  3. Srinivasan S, et al. Overview of fetal arrhythmias. Current Opinion in Pediatrics. 2008;20:522.
  4. Brennand J, et al. Fetal anaemia: Diagnosis and management. Best Practice & Research Clinical Obstetrics and Gynaecology. 2008;22:15.
  5. Kalyani R, et al. Twin reversed arterial perfusion syndrome (TRAP or acardiac twin): A case report. Journal of Clinical and Diagnostic Research. 2014;8:166.
  6. Djaafri F, et al. Twin-twin transfusion syndrome: What we have learned from clinical trials. Seminars in Fetal and Neonatal Medicine. 2017;22:367.
  7. D'Antonio F, et al. Prenatal risk factors and outcomes in gastroschisis: A meta-analysis. Pediatrics. 2015;136: e159. http://pediatrics.aappublications.org/content/136/1/e159. Accessed Feb. 8, 2018.
  8. Alpha-fetoprotein (AFP), single marker screen, maternal, serum. Mayo Medical Laboratories. https://www.mayomedicallaboratories.com/test-catalog/clinical+and+interpretive/81169. Accessed Feb. 8, 2018.
  9. AskMayoExpert. Prenatal screening and testing. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2017.
  10. Screening for fetal anomalies. National Institutes of Health. https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0009593/. Accessed Feb. 9, 2018.
  11. Baer RJ, et al. 311: Risk of preterm birth by subtype of infants with gastroschisis. American Journal of Obstetrics and Gynecology. 2017;216:S190.
  12. Wyllie R, et al., eds. Abnormal rotation and fixation of the intestine. In: Pediatric Gastrointestinal and Liver disease. 5th ed. Philadelphia, Pa.: Elsevier; 2016. https://www.clinicalkey.com. Accessed Feb. 12, 2018.
  13. Lee H, et al. Efficacy of radiofrequency ablation for twin-reversed arterial perfusion sequence. American Journal of Obstetrics and Gynecology. 2007;196:e1.
  14. Wee LY, et al. The twin-twin transfusion syndrome. Seminars in Neonatology. 2002;7:187.
  15. Ruano R (expert opinion). Mayo Clinic, Rochester, Minn. Feb. 13, 2018.
  16. Famuyide AO (expert opinion). Mayo Clinic, Rochester, Minn. March 1, 2018.
  17. Magtibay PM (expert opinion). Mayo Clinic, Phoenix/Scottsdale, Ariz. March 1, 2018.
  18. Amanda Ullom [contact for obstetrics and gynecology volumes]. MSS (Mayo Scheduling System). Mayo Clinic, Rochester, Minn. Feb. 27, 2018.

Mayo Clinic in Rochester, Minn., has been recognized as one of the best Gynecology hospitals in the nation for 2019-2020 by U.S. News & World Report.

Learn more about this top honor

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