Jeffrey R. Janus, M.D.

  1. Otolaryngologist

Specialty Groups


  1. Jacksonville, Florida



Dr. Jeffrey R. Janus is currently the Chair of the Department of Otolaryngology at Mayo Clinic in Jacksonville, Florida. He is a board certified, fellowship trained, Head and Neck Oncologic and Reconstructive Surgeon. Dr. Janus trained at the University of Florida College of Medicine in Gainesville, Florida where he received entrance into the Junior Honors Medical Program, combining the last year of undergraduate training and the first year of medical school. He was at the Mayo Clinic in Rochester, Minnesota from 2008-2019 as an Otolaryngologist, Head and Neck Surgeon. In early 2020, Dr. Janus transferred to Mayo Clinic Florida to continue his work. Dr. Janus's interests include:

  • Salivary tumor (Parotid Gland) Surgery with special focus on postoperative facial nerve function and aesthetics
  • Removal and reconstruction of Head and Neck Cancers with concentration on restoration of pre-morbid form and function. These cases are often done with preoperative 3D planning and 3D printing of patient specific tools.
  • Endocrine Surgery — removal of thyroid and parathyroid tumors with consideration of voice function
  • Robotic Surgery — the use of the surgical robot to remove tumors of the throat (oropharynx) and voice box (larynx)
  • Multidisciplinary Head and Neck Cancer Clinic — this is a group of Head and Neck Surgeons, Radiation Oncologists, Medical Oncologists, Pathologists, Radiologists, and other staff who meet regularly at Mayo Clinic Florida to review complex cases and compose multidisciplinary treatment plans.
  • Minimally invasive (endoscopic) approaches to the skull base and pituitary gland

In addition to his clinical activities, Dr. Janus' is active in research and education, providing mentorship to residents and fellows. He authors expert content and publishes in high-impact scientific journals and actively collaborates with the center for regenerative medicine and the cancer center.

  1. Mouth cancer
  2. Oropharyngeal cancer
  3. Parathyroid adenoma
  4. Salivary gland tumor
  5. Skull base tumor
  6. Soft palate cancer
  7. Throat cancer
  8. Thyroid cancer
  1. Head and neck cancer surgery
  2. Head and neck reconstruction
  3. Microvascular surgery
  4. Neck surgery
  5. Parathyroidectomy
  6. Parotid gland surgery
  7. Robotic surgery
  8. Thyroidectomy
  9. Transnasal endoscopic procedure
  10. Transnasal pituitary surgery
  11. Transoral robotic surgery
  • Microvascular Reconstruction — Free flap surgery, the use of tissue from one place in the body to rebuild a surgical defect at another, restoring preoperative form and function when possible.
Microvascular Reconstruction
  • Parotid Surgery — Removal of benign and malignant parotid tumors, with special consideration postoperative facial nerve function and/or facial reanimation.
Parotid Surgery
  • Endocrine Surgery — The removal of parathyroid and thyroid tumor with focus voice preservation
Endocrine Surgery
  • Endoscopic Skull Base Surgery — Removal of nasal tumors and/or brain tumors through the nose, done in conjunction with neurosurgery, to avoid large incisions on the face and head.
Endoscopic Skull Base Surgery
  • Robotic Surgery — The use of a small 3D camera and robotic arms to remove tumors of the upper aerodigestive tract (e.g. Oropharynx and/or throat cancer).
Robotic Surgery
  • Oral Cavity Cancer Surgery — Removal of tumors from the mouth, lips, cheek, jaw, and tongue with special consideration of reconstruction when needed, and restoration of preoperative speech and swallow when possible.
Oral Cavity Cancer Surgery
  • Regenerative Medicine Research — The use of stem cells and tissue scaffolding to rebuild or repair natural structures in the head and neck.
Regenerative Medicine Research
  1. 2014
    Mayo Clinic ScholarAdvanced Head & Neck Oncologic and Reconstructive Surgery Fellowship, Department of Otorhinolaryngology
  2. 2013
    Chief ResidentOtorhinolaryngology Residency, Department of Otorhinolaryngology
  3. 2012
    ResidentOtorhinolaryngology Residency, Department of Otorhinolaryngology
  4. 2008
    Doctorate of MedicineUniversity of Florida College of Medicine
  5. 2005
    BSInterdisciplinary Degree of the Biological and Medical Sciences, University of Florida


  1. 2014
    Otolaryngology - Head & Neck SurgeryAmerican Board of Otolaryngology - Head and Neck Surgery

Awards and honors

  1. 2019
    Teacher of the Year (2019) - OtolaryngolgoyMayo Fellows Association, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine and Science
  2. 2014
    Career Development Award - $250,000 for research Center for Regenerative Medicine
  3. 2013
    Wellness Challenge Overall WinnerMayo Fellows Association
  4. 2008
    Otolaryngology Research AwardDepartment of Otolaryngology, University of Florida
  5. 2007
    Chapman Chapter of the Gold Humanism Honor SocietyUniversity of Florida
  6. 2005
    Medical Science Research Program Stipend for Type I DiabetesUniversity of Florida

Professional memberships

  1. 2020 - present
    FellowAmerican College of Surgeons
  2. 2020 - present
    MemberSurgical and Procedural Committee
  3. 2020 - present
    Executive Committee Member2020 Center Regenerative Medicine Florida Leadership Committee
  4. 2015 - 2020
    ChairResearch Committee, Department of Otorhinolaryngology
  5. 2015 - present
    North American Skull Base Society
  6. 2015 - 2020
    MemberENT Quality Assurance Committee, Department of Otorhinolaryngology, Mayo Clinic in Rochester
  7. 2014 - 2020
    MemberEducation Committee
  8. 2012 - present
    MemberAmerican Head and Neck Society
  9. 2012 - present
    MemberMinnesota Academy of Otolaryngology
  10. 2008 - present
    MemberAmerican Academy of Otolaryngology - Head and Neck Surgery


Research activities

See a description of research activities.