Biographical summary
Dr. Ruff specializes in the treatment of cancers arising from the nervous system, as well as the neurologic complications of systemic cancers and their treatment.
His primary research interest is clinical trial development and cell based therapies (CAR-T therapy) for CNS malignancies.
Conditions treated
Procedures performed
Interests
- Glioma and the complications of its treatment.
- Neurocutaneous syndromes.
- Experimental therapeutics in neuro-oncology.
- CAR-T associated complications.
- CAR-T development for malignant glioma.
Mayo Clinic locations
Rochester, Minnesota
Education
- 2018
FellowRST Neuro-Oncology, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
- 2017
ResidentNeurology, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
- 2017
InternshipMayo Graduate School of Medical Education
- 2013
MDUniversity of Missouri School of Medicine
- 2009
BS - BiologyMissouri State University
Activities and honors
Certifications
- 2022
Brain Injury MedicineAmerican Board of Psychiatry and Neurology
- 2017
NeurologyAmerican Board of Psychiatry and Neurology
Awards and honors
- 2025
2025 Department of Medicine Bold Forward Advancements Award for Inpatient Clinical PracticeDepartment of Internal Medicine
- 2013
Dean's Research AwardUniversity of Missouri School of Medicine
- 2012
Medical Student Prize for Excellence in NeurologyAmerican Academy of Neurology
- 2009
Horace E. Thomas and Helen Y. Thomas Medical Student ScholarshipUniversity of Missouri School of Medicine
- 2009
Phi Kappa Phi Honor Society
- 2008
Sechler Family Scholarship RecipientMissouri State University
- 2008
M&B Ingram Endowed Scholarship recipientMissouri State University
- 2007
Grant recipientMissouri Access Program
- 2007
SMART Grant recipientUnited States Department of Education
Professional memberships
- 2025
MemberGlioma Center of Excellence Advisory Board, Servier US
- 2025 - present
MemberCAR-T Neuro think tank
- 2025 - present
2022 Annual Meeting Planning CommitteeAmerican Academy of Neurology
- 2025 - present
Co-FounderLeading Undergraduate Medical Education in Neurology (LUMEN)
- 2025 - present
MemberNeuro-Oncology Program, Mayo Clinic Cancer Center
- 2023 - present
MemberStaff Wellness Committee, Department Committees, Department of Nursing
- 2023 - present
MemberEnterprise Cell Therapy Committee
- 2021
Moderator/Co-ChairAmerican Academy of Neurology
- 2021 - present
2021 Annual Meeting Planning CommitteeAmerican Academy of Neurology
- 2019 - present
Committee MemberCellular, Molecular, and Bispecific Therapies (CMB) Steering Committee
- 2019 - present
Commiittee MemberCMB Cell and Engagers Subcommittee
- 2019 - present
MemberMCCC Cell Therapy Group
- 2018 - present
MemberEuropean Association for Neuro-Oncology
- 2017
MemberResident Nurse Counsel, Department of Neurology
- 2017 - present
MemberAmerican Academy of Neurology
- 2016 - 2017
MemberMayo Neurology Resident Curriculum Committee, Department of Neurology
- 2016 - present
MemberSociety for Neuro-Oncology
- 2016 - present
MemberAmerican Society of Clinical Oncology
- 2015 - 2017
MemberResidency Recruitment Committee, Department of Neurology