Samuel Han, M.D.

Samuel Han, M.D., is a gastroenterologist and advanced endoscopist at Mayo Clinic in Rochester, Minnesota, caring for people in the region and from all around the world. Dr. Han specializes in the diagnosis and minimally invasive treatment of complex pancreatic and biliary disorders, with a focus on improving quality of life for individuals facing acute and chronic conditions. He offers advanced therapeutic options tailored to each patient's needs.

"I aim to treat patients with love and respect with the goal of improving their quality of life," says Dr. Han.

Outside of his clinical practice, Dr. Han enjoys scuba diving, traveling, and discovering great BBQ.

Dr. Han provides specialized care for conditions of the pancreas and biliary system, using advanced endoscopic techniques designed to relieve pain, restore function and optimize health.

• Chronic and acute pancreatitis: Comprehensive management, including minimally invasive interventions
• Pancreatic cancer: Diagnostic evaluation and endoscopic therapy to support treatment planning
• Necrotizing pancreatitis: Endoscopic management of complications and ductal disorders
• Disconnected pancreatic duct syndrome: Advanced endoscopic solutions to restore continuity
• Biliary obstruction: Endoscopic therapy for complex bile duct strictures

Procedures performed

• Endoscopic ultrasound (EUS): Imaging and fine-needle biopsy for accurate diagnosis
• Endoscopic retrograde cholangiopancreatography (ERCP): Therapeutic interventions for pancreatic and biliary diseases
• Cholangioscopy and pancreatoscopy: Direct visualization and targeted therapy for strictures and stones
• Extracorporeal shockwave lithotripsy (ESWL): Stone fragmentation for pancreatic duct stones

Dr. Han serves as Senior Associate Consultant in the Division of Gastroenterology and Hepatology at Mayo Clinic and Associate Professor of Medicine at Mayo Clinic College of Medicine and Science. Board-certified in internal medicine and gastroenterology, he completed his medical degree, residency, and chief residency at the University of Massachusetts Medical School, followed by fellowship and advanced fellowship in therapeutic endoscopy at the University of Colorado.

His academic work focuses on improving endoscopic techniques, optimizing outcomes for patients with chronic pancreatitis, and advancing education in therapeutic endoscopy. Dr. Han has authored numerous peer-reviewed publications and is active in multiple professional societies, including the American Society for Gastrointestinal Endoscopy, where he holds leadership roles.