Quality CareFind out why Mayo Clinic is the right place for your health care. Make an appointment.
Meet the StaffFind a directory of doctors and departments at all Mayo Clinic campuses. Visit now.
Research and Clinical TrialsSee how Mayo Clinic research and clinical trials advance the science of medicine and improve patient care. Explore now.
Visit Our SchoolsEducators at Mayo Clinic train tomorrow’s leaders to deliver compassionate, high-value, safe patient care. Choose a degree.
Professional ServicesExplore Mayo Clinic’s many resources and see jobs available for medical professionals. Get updates.
Give to Mayo ClinicHelp set a new world standard in care for people everywhere. Give now.
Subscribe to Housecall
Our general interest e-newsletter keeps you up to date on a wide variety of health topics.
Doctors prescribe alpha blockers to prevent, treat or improve symptoms in conditions such as:
Though alpha blockers are commonly used to treat high blood pressure, they're typically not preferred as the first treatment option. Instead, they're used in combination with other drugs, such as diuretics, when your high blood pressure is difficult to control.
Alpha blockers may have what's called a "first-dose effect." When you start taking an alpha blocker, you may develop pronounced low blood pressure and dizziness, which can make you suddenly faint when you rise from a sitting or lying position. As a result, the first dose is often taken at bedtime.
Other side effects include headache, pounding heartbeat, nausea, weakness, weight gain and small decreases in low-density lipoprotein (LDL) cholesterol (the "bad" cholesterol).
Alpha blockers can increase or decrease the effects of other medications you take. Tell your doctor if you take any other medications, such as beta blockers, calcium channel blockers or medications used for erectile dysfunction, if you're prescribed an alpha blocker.
Some research has found that some alpha blockers can increase the risk of heart failure with long-term use. While more research is needed to confirm this finding, talk to your doctor if you're concerned.
Mayo Clinic does not endorse companies or products. Advertising revenue supports our not for profit mission.
Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.
A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.
We comply with the HONcode standard for trustworthy health information: verify here.