Matthew T. Houdek, M.D.

  1. Orthopedic Surgeon
  2. Surgical Oncologist



  1. Rochester, Minnesota



Matthew T. Houdek, M.D., is an Associate Professor of Orthopedic Surgery and the Fellowship Director for Musculoskeletal Oncology at the Mayo Clinic. He received his MD from the University of Arizona. He went on to be trained in Orthopedic Surgery at Mayo Clinic, and then did his fellowship training in Musculoskeletal Oncology at the University Musculoskeletal Oncology Unit at Mount Sinai Hospital and University of Toronto.

Dr. Houdek is an orthopedic oncologist treating both children and adults with bone and soft-tissue sarcomas of the pelvis and extremities. Dr. Houdeks' clinical and research interest include outcomes of complex reconstruction and limb salvage, with a focus on upper extremity sarcomas.

  1. Amputation
  2. Joint replacement surgery
  3. Limb salvage surgery
  4. Rotationplasty
  • Extremity Soft Tissue Sarcoma
  • Extremity Bone Sarcoma
  • Upper Extremity Sarcoma
  • Hand Sarcoma
  • Pelvic Sarcoma
  • Limb Salvage and Reconstruction
  • Pediatric Sarcoma
  • Metastatic Bone Disease
  • Tissue Regeneration
  • Wound Healing
  1. 2017
    Fellowship - Orthopedic OncologyMount Sinai Hospital, University of Toronto
  2. 2016
    ResidentOrthopedic Surgery, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  3. 2016
    MS - Orthopedic SurgeryMayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic College of Medicine and Science
  4. 2011
    MD - MedicineUniversity of Arizona College of Medicine
  5. 2005
    BS - BiologyUniversity of Redlands


  1. 2019
    Orthopedic SurgeryAmerican Board of Orthopaedic Surgery

Awards and honors

  1. 2019
    2nd Best Clinical Paper - 2019 Annual MeetingMusculoskeletal Tumor Society
  2. 2019
    3rd Best Clinical Paper - 2019 Annual MeetingMusculoskeletal Tumor Society
  3. 2019
    Best Clinical PaperInternational Society of Limb Salvage Surgery (ISOLS)
  4. 2019
    CORR® ORS Richard A. Brand Award: Disruption in Peroxisome Proliferator-Activated Receptor-? (PPARG) Increases Osteonecrosis Risk Through Genetic Variance and Pharmacologic ModulationOrthopedic Research Society
  5. 2017
    3rd Best Clinical paper at 2017 annual meetingMusculoskeletal Tumor Society
  6. 2016
    H.A. Peterson Best Clinical PaperMayo Clinic Department of Orthopedic Surgery
  7. 2015
    Best Clinical PaperH.A. Peterson Scholarly Writing Competition Award
  8. 2015
    Chitranjan Ranawat AwardKnee Society
  9. 2013
    AAOS Clinician Scholar Development ProgramAmerican Academy of Orthopaedic Surgeons
  10. 2012
    Best Poster "Successful Prosthetic Rehabilitation Following Hip Disarticulation and Hemipelvectomy"Mayo Clinic Young Investigators Research Symposium 2012
  11. 2011
    Alpha Omega Alpha Honor Medical SocietyUniversity of Arizona College of Medicine
  12. 2011
    Honors in Research AwardUniversity of Arizona College of Medicine
  13. 2001
    Varsity LetterMen's NCAA Basketball Team, University of Redlands

Professional memberships

  1. 2020 - present
    MemberMid-America Orthopaedic Association
  2. 2019 - present
    Career AdvisorCareer Advisory Program, Mayo Clinic Alix School of Medicine, Mayo Clinic in Arizona
  3. 2019 - present
    ContributorAmerican College of Surgeons
  4. 2019 - present
    ChairMasters' Thesis Committees, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic College of Medicine and Science
  5. 2017 - present
    MemberMusculoskeletal Tumor Society
  6. 2017 - present
    MemberChildren's Oncology Group
  7. 2016 - present
    Candidate MemberAmerican Academy of Orthopaedic Surgeons
  8. 2016 - present
    MemberInternational Society of Limb Salvage