Below are current clinical trials.6 studies in Heart valve surgery
(open studies only).
Filter this list of studies by location, status and more.
This study is designed to determine if point-of-care washing of allogeneic Leukocyte-Reduced Red Blood Cells reduces pulmonary complications when compared to standard-of-care Leukocyte-Reduced Red Blood Cells in a cardiac surgical population.
The purpose of this study is to look at liver stiffness with a MRI sequence called Magnetic Resonance Elastography (MRE). The study will let the investigators know whether the subject's liver is normal or has increased stiffness. Increased liver stiffness often means there is chronic liver disease and fibrosis. Increased right heart pressure and congestive heart failure are considered risk factors for development of liver fibrosis. Liver fibrosis, if progressive, may lead to cirrhosis and its related complications. The increased liver stiffness may be due to a poorly functioning tricuspid valve. With this research, the investigators will be able to determine if the elevated stiffness of the liver returns to normal after the surgeon performs a repair or replacement of the tricuspid valve.
The objective of this study is to evaluate the safety and performance of the Trifecta™ GT (Glide Technology) valve through 5 year follow-up in a prospective, multi-center, real-world setting. This study is intended to satisfy post-market clinical follow-up requirements of CE Mark in Europe.
The purpose of the research is to determine whether repairing a tricuspid valve (TV) in patients with mild to moderate tricuspid regurgitation (TR), at the time of planned mitral valve surgery (MVS), would improve the heart health of those who receive it compared to those who do not. At this point, the medical community is split in their opinion on whether surgeons should routinely repair mild to moderate TR in patients who are undergoing planned mitral valve surgery, and this study will answer this question.
The goal of this study is to create a comprehensive system of blood and tissue banking of samples from Mayo Clinic Arizona patients with a clinical diagnosis of aortic stenosis who are either undergoing routine care at Mayo Clinic or undergoing aortic valve surgery. The tissue samples will be used for future research of aortic stenosis at Mayo Clinic and future research at Mayo Clinic to learn about, prevent, or treat other health problems.
The purpose of this study is to provide a survey to prospective candidates undergoing transcatheter valve replacement or repair at two time-points to assess grit, a psychological composite of personal diligence which has been validated to predict retention in other pursuits of long-term goals over and above assessments limited to intelligence and physical aptitude.
March 03, 2017
- What is heart surgery? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/hs. Accessed Sept. 23, 2016.
- What is heart valve disease? National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/hvd. Accessed Aug. 15, 2016.
- Barbara Woodward Lips Patient Education Center. Getting ready for heart surgery. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2011.
- How can I prepare for heart surgery? American Heart Association. https://www.nlm.nih.gov/medlineplus/heartsurgery.html. Accessed Sept. 25, 2016.
- Taggarse AK, et al. How has robotic repair changed the landscape of mitral valve surgery? Annals of Cardiothoracic Surgery. 2015;4:358.
- Aldea GS. Minimally invasive aortic and mitral valve surgery. http://www.uptodate.com/home. Accessed Aug. 15, 2016.
- Vernick W, et al. Robotic and minimally invasive cardiac surgery. Anesthesiology Clinics. 2013;31:299.
- Bonow RO, et al., eds. Valvular heart disease. In: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 10th ed. Philadelphia, Pa.: Saunders Elsevier; 2015. http://www.clinicalkey.com. Accessed Aug. 16, 2016.
- Ruiz CE, et al. Transcatheter therapies for the treatment of valvular and paravalvular regurgitation in acquired and congenital valvular heart disease. Journal of the American College of Cardiology. 2015;66:169.
- Riggin EA. Allscripts EPSi. Mayo Clinic, Rochester, Minn. Sept. 23, 2016.
- Nishimura RA, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. The Journal of Thoracic and Cardiovascular Surgery. 2014;148:e1.
- AskMayoExpert. Mitral regurgitation. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2016.
- Stulak JM (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 28, 2016.
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