Primary biliary cholangitis (PBC)

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Displaying 1-2 out of 2 doctors available

Last Name Initial: C

  1. Elizabeth J. Carey, M.D.

    Elizabeth J. Carey, M.D.

    1. Internist
    2. Gastroenterologist
    3. Transplant Hepatologist
    1. Phoenix, AZ
    Areas of focus:

    Liver transplant, Primary sclerosing cholangitis, Primary biliary cholangitis, Nonalcoholic fatty liver disease, Cirrho...sis, Autoimmune hepatitis, Alcoholic hepatitis, Hepatic encephalopathy

  2. Alex Cortez, M.D.

    Alex Cortez, M.D.

    1. Transplant Surgeon
    1. Rochester, MN
    Areas of focus:

    Liver transplant, Kidney transplant, Robotic surgery, Cholecystectomy, Liver resection, Hernia repair, Liver cyst fenes...tration, Cholangiocarcinoma, Primary sclerosing cholangitis, Polycystic kidney disease, Hepatocellular carcinoma, Primary biliary cholangitis, Cirrhosis, Acute liver failure, Autoimmune hepatitis, Liver cancer, End-stage renal disease, Alcoholic liver disease, Portal hypertension, Chronic liver disease, Budd-Chiari syndrome, Metabolic liver disease, Polycystic liver disease

Research

Mayo Clinic has been conducting research on primary biliary cholangitis for more than 50 years. Many treatments for the disease have been studied at Mayo Clinic. Mayo Clinic was one of the first centers to study ursodiol as a treatment option. Researchers are currently studying new medicines and combinations of therapies for people with only a partial response to ursodiol.

Researchers at Mayo Clinic have made many contributions to understanding the genetics of primary biliary cholangitis (PBC). They've helped find several gene variations that seem to make people more likely to develop the disease. Their discoveries are the first step toward developing targeted treatments and potentially curing the disease.

Also, researchers at Mayo Clinic have found that first-degree relatives — parents, siblings or children — of people with the disease are more likely to carry an antibody related to PBC. The finding suggests that a simple blood test may help healthcare professionals monitor people for early signs of PBC.

Basic research related to PBC and other liver diseases is conducted in the following Mayo Clinic laboratories:

Publications

See a list of publications about primary biliary cholangitis by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

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By Mayo Clinic Staff

Primary biliary cholangitis (PBC) care at Mayo Clinic

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Diagnosis & treatmentCare at Mayo Clinic
Feb. 27, 2026
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Primary biliary cholangitis (PBC)

Research: It's all about patients

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Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight.