Diagnosis

A health care provider's goal in evaluating orthostatic hypotension is to find the cause and determine treatment. The cause isn't always known.

A care provider might review medical history, medications and symptoms and conduct a physical exam to help diagnose the condition.

A provider also might recommend one or more of the following:

  • Blood pressure monitoring. This involves measuring blood pressure while sitting and standing. A drop of 20 millimeters of mercury (mm Hg) in the top number (systolic blood pressure) within 2 to 5 minutes of standing is a sign of orthostatic hypotension. A drop of 10 mm Hg in the bottom number (diastolic blood pressure) within 2 to 5 minutes of standing also indicates orthostatic hypotension.
  • Blood tests. These can provide information about overall health, including low blood sugar (hypoglycemia) or low red blood cell levels (anemia). Both can cause low blood pressure
  • Electrocardiogram (ECG or EKG). This quick and painless test measures the electrical activity of the heart. During an ECG, sensors (electrodes) are attached to the chest and sometimes to the arms or legs. Wires connect to a machine, which prints or displays results. An ECG can show changes in the heart rhythm or heart structure and problems with the supply of blood and oxygen to the heart muscle.

    An ECG may not detect occasional heart rhythm changes. Your health care provider may recommend monitoring your heartbeat at home. A portable ECG device, called a Holter monitor, can be worn for a day or more to record the heart's activity during daily activities.

  • Echocardiogram. Sound waves are used to create pictures of the heart in motion. An echocardiogram can show blood flow through the heart and heart valves. The test can help identify structural heart disease.
  • Stress test. A stress test is done during exercise, such as walking on a treadmill. People who can't exercise might be given medication to make the heart work harder. The heart is then monitored with electrocardiography, echocardiography or other tests.
  • Tilt table test. A tilt table test shows how the body reacts to changes in position. It involves lying on a flat table that tilts to raise the upper part of the body. The changes in position mimic the movement from lying down to standing. Blood pressure is taken frequently as the table is tilted.
  • Valsalva maneuver. This noninvasive test determines how well the autonomic nervous system is working. It requires breathing in deeply and pushing the air out through the lips, as though trying to blow up a stiff balloon. Heart rate and blood pressure are checked during the test.

Treatment

Treatment for orthostatic hypotension is directed at the cause rather than the low blood pressure itself. For example, if dehydration causes orthostatic hypotension, your health care provider may suggest lifestyle changes such as drinking more water. If a medication causes low blood pressure when standing, treatment may involve changing the dose or stopping the drug.

For mild orthostatic hypotension, one of the simplest treatments is to sit or lie back down immediately after feeling lightheaded upon standing. Often, symptoms will disappear. Sometimes, medications are needed to treat orthostatic hypotension.

Medications

If orthostatic hypotension doesn't improve with lifestyle changes, medications may be needed to increase blood pressure or blood volume. The type of medication depends on the type of orthostatic hypotension.

Drugs that may be used to treat orthostatic hypotension include midodrine (Orvaten), droxidopa (Northera), fludrocortisone or pyridostigmine (Mestinon, Regonol).

Talk to your health care provider about the risks and benefits of these drugs to determine which one is best for you.

Clinical trials

Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.

Lifestyle and home remedies

Some simple steps can help manage or prevent orthostatic hypotension. These include:

  • Wearing waist-high compression stockings. These may help improve blood flow and reduce the symptoms of orthostatic hypotension. Wear them during the day, but take them off for bed and when lying down.
  • Getting plenty of fluids. Keeping hydrated helps prevent symptoms of low blood pressure. Drink plenty of water before long periods of standing, or any activities that tend to trigger symptoms.
  • Avoiding alcohol. Alcohol can worsen orthostatic hypotension, so limit or avoid it completely.
  • Increasing salt in the diet. This must be done carefully and only after discussing it with a health care provider. Too much salt can cause blood pressure to increase beyond a healthy level, creating new health risks.
  • Eating small meals. If blood pressure drops after eating, having small, low-carbohydrate meals might help.
  • Exercising. Regular cardiovascular and strengthening exercises might help reduce symptoms of orthostatic hypotension. Avoid exercising in very hot, humid weather.
  • Moving and stretching in certain ways. Stretch and flex calf muscles before sitting up. For symptoms, squeeze thighs together and squeeze stomach and buttock muscles. Squat, march in place or rise onto tiptoes.
  • Getting up slowly. Move slowly from a lying to standing position. Also, when getting out of bed, sit on the edge of the bed for a minute before standing.
  • Raising the head of the bed. Sleeping with the head of the bed slightly raised can help fight the effects of gravity.

Preparing for your appointment

You don't need to do anything special before having your blood pressure checked. But it's helpful to wear a short-sleeved shirt or a loose long-sleeved shirt that can be pushed up during the test. Doing so helps with fitting the blood pressure cuff around the arm properly.

Take your blood pressure regularly at home, and keep a log of your readings. Bring the log with you to your health care provider's appointment.

Take your blood pressure first thing in the morning. Lie down for the first reading. Complete taking your blood pressure, then wait one minute. Stand and take the second reading.

Also take your blood pressure at these times:

  • After you eat
  • When your symptoms are least severe
  • When your symptoms are most severe
  • When you take your blood pressure medications
  • One hour after you take your blood pressure medications

Here's some information to help you get ready for your appointment.

What you can do

When you make the appointment, ask if there's anything you need to do in advance, such as restrict your diet for a blood test. Plan to bring a family member or friend to your appointment, if possible, to help you remember all the information you're given.

Make a list of the following:

  • Your symptoms, including any that may seem unrelated to low blood pressure, what triggers them and when they began.
  • Key personal information, including a family history of low blood pressure and major stresses or recent life changes.
  • All medications, vitamins or supplements you take, including doses. Or bring in the bottles of all the medications you take.

    Some medications — such as cold medicines, antidepressants, birth control pills and others — can affect your blood pressure. Don't stop taking any prescription medications that you think might affect your blood pressure without your care provider's advice.

  • Questions to ask your care provider.

    Be prepared to discuss your diet and exercise habits, especially the amount of salt in your diet. If you don't already follow a diet or exercise routine, be ready to talk to your provider about challenges you might face in getting started.

For orthostatic hypotension, questions to ask your health care provider include:

  • What's the most likely cause of my symptoms?
  • Could my medications be a factor?
  • What are other possible causes for my symptoms or condition?
  • What tests will I need?
  • What's the most appropriate treatment?
  • How often should I be screened for low blood pressure? Should I measure it at home?
  • I have other health conditions. How can I best manage these conditions together?
  • Do I need to follow any diet or activity restrictions?
  • Are there any brochures available? What websites do you recommend?

Don't hesitate to ask other questions.

What to expect from your doctor

Your health care provider will likely ask you questions, such as:

  • How often do you have symptoms?
  • How severe are your symptoms?
  • What, if anything, seems to improve your symptoms?
  • What, if anything, appears to worsen your symptoms?
  • Do you ever temporarily stop taking your medications because of side effects or because of the expense?
May 26, 2022
  1. Orthostatic hypotension. Merck Manual Professional Version. https://www.merckmanuals.com/professional/cardiovascular-disorders/symptoms-of-cardiovascular-disorders/orthostatic-hypotension. Accessed March 5, 2022.
  2. Palma J, et al. Mechanisms, causes, and evaluation of orthostatic hypotension. https://www.uptodate.com/contents/search. Accessed March 5, 2022.
  3. AskMayoExpert. Orthostatic hypotension. Mayo Clinic; 2021.
  4. Orthostatic hypotension information page. National Institute of Neurological Disorders and Stroke. https://www.ninds.nih.gov/Disorders/All-Disorders/Orthostatic-Hypotension-Information-Page. Accessed March 5, 2022.
  5. Palma J, et al. Treatment of orthostatic and postprandial hypotension. https://www.uptodate.com/contents/search. Accessed March 5, 2022.
  6. Shen WK, et al. 2017 ACC/AHA/HRS guideline for the evaluation and management of patients with syncope. Heart Rhythm. 2017; doi:10.1016/j.hrthm.2017.03.004.
  7. Peixoto AJ. Evaluation and management of orthostatic hypotension: Limited data, limitless opportunity. Cleveland Clinic Journal of Medicine. 2022; doi:10.3949/ccjm.89gr.22001.
  8. Magkas N, et al. Orthostatic hypotension: From pathophysiology to clinical applications and therapeutic considerations. Journal of Clinical Hypertension. 2019; doi:10.1111/jch.13521.

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Orthostatic hypotension (postural hypotension)