Moyamoya disease care at Mayo Clinic

Your Mayo Clinic care team

Mayo Clinic neurologists, neurosurgeons, neuroradiologists and moyamoya specialists work together to evaluate and treat people with moyamoya disease and other brain and blood vessel conditions (cerebrovascular diseases). Our team is multidisciplinary and dedicated to moyamoya patients.

Our team of Mayo Clinic experts provides comprehensive treatment for people with moyamoya disease. Our experts not only address vascular risk but also provide therapies to minimize cognitive and developmental issues and ensure that our patients live healthy and productive lives. Our experts treat each person individually, using specialists in occupational, behavioral and physical therapy as needed.

Advanced diagnosis and treatment

Mayo Clinic moyamoya specialists offer a range of the latest tools and techniques to diagnose and treat moyamoya disease. Diagnostic options include:

Mayo Clinic moyamoya disease specialists have the expertise to combine the results of these diagnostic tests with cognitive assessments to better understand how the disease is affecting your quality of life and use this information to personalize your treatment plan. In addition, our team includes specialists with expertise in moyamoya, stroke and headaches, leading to an integral management of symptoms.

Mayo Clinic surgeons have extensive experience treating moyamoya disease using many sophisticated surgical techniques, including direct and indirect revascularization procedures. With access to advanced 3D imaging technology, Mayo Clinic moyamoya specialists can show you precisely what's going on with your condition and use 3D models to simulate surgical procedures.

Learn more about Mayo Clinic's neurology and neurosurgery departments' expertise and rankings.

Individualized, efficient care

At Mayo Clinic, your doctor will provide you or your child with individualized care to help you manage the condition. Doctors at Mayo will also coordinate your follow-up care with your primary doctor.

A detailed itinerary for appointments, tests and procedures prepared for your visit lets you make the most of your time at the clinic. Mayo staff runs all tests and labs at Mayo Clinic, which means tests taken in the morning can be reviewed the same day.

Moyamoya disease expertise and rankings


Mayo Clinic doctors have extensive experience in diagnosing and treating moyamoya disease, although it's a rare condition. Moyamoya disease generally occurs in fewer than 1 in 100,000 people. Mayo Clinic doctors evaluate and treat more than 180 people each year with moyamoya disease.

Advanced surgical techniques

Mayo Clinic surgeons treat moyamoya disease using several sophisticated surgical techniques, including direct and indirect revascularization procedures. Types of indirect revascularization procedures include encephaloduroarteriosynangiosis (EDAS) or encephalomyosynangiosis (EMS), or a combination of both.

Mayo Clinic surgeons also use the latest in 3D imaging to continuously refine and improve their technique and outcomes.


Mayo Clinic neurologists actively research causes, diagnostic tests and new treatments for many brain and blood vessel conditions (cerebrovascular diseases), including moyamoya disease. Doctors conduct research and review medical histories to learn how diseases progress, how to treat them and which treatments may be most appropriate for people.

A variety of clinical trials and other clinical studies may be available to you at Mayo Clinic.

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Jacksonville, Florida, and Mayo Clinic in Phoenix/Scottsdale, Arizona., rank among the Best Hospitals for neurology and neurosurgery and for cancer in the U.S. News & World Report rankings. Mayo Clinic Children's Center in Rochester is ranked the No. 1 hospital in Minnesota, and the five-state region of Iowa, Minnesota, North Dakota, South Dakota and Wisconsin, according to U.S. News & World Report's 2023–2024 "Best Children's Hospitals" rankings. With the emphasis on collaborative care, specialists interact very closely with their colleagues across all sites.

Mayo Clinic Children's Center

Highly skilled pediatric experts diagnose and treat all types of conditions in children. As a team, we work together to find answers, set goals and develop a treatment plan tailored to your child's needs.

Learn more about the Children's Center.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals, or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

Mayo Clinic Moyamoya Clinic


  • 5779 E Mayo Blvd
    Phoenix, AZ 85054
  • Phone: 480-301-8000


  • 4500 San Pablo Road
    Jacksonville, FL 32224
  • Phone: 904-953-0856


  • 200 1st St SW, Floor 8
    Rochester, MN 55905
  • Phone: 507-284-2111
April 18, 2023