Lynch syndrome

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Departments and specialties

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

Departments that treat this condition

Doctors who treat this condition

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Research

Mayo Clinic researchers are actively investigating new ways to identify and care for people with Lynch syndrome, as well as novel opportunities for cancer prevention.

Mayo Clinic doctors have made many important discoveries that have contributed to the improved care of people with Lynch syndrome. For instance, Mayo Clinic researchers were among the first to recognize microsatellite instability in cancer cells and developed a microsatellite instability (MSI) tumor test for identifying Lynch syndrome in people with colon cancer. MSI tumor testing helps identify which cancers are most likely to be caused by Lynch syndrome.

Publications

See a list of publications on Lynch syndrome by Mayo Clinic authors on PubMed, a service of the National Library of Medicine.

Research Profiles

By Mayo Clinic Staff

Lynch syndrome care at Mayo Clinic

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Diagnosis & treatmentCare at Mayo Clinic
Jan. 23, 2025
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Living with lynch syndrome?

Connect with others like you for support and answers to your questions in the Colorectal Cancer support group on Mayo Clinic Connect, a patient community.

Colorectal Cancer Discussions

Teresa, Volunteer Mentor
How do I eat after digestive tract surgery?

52 Replies Thu, Aug 21, 2025

lucy155
Post colon resection abdominal hernia

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Lynch syndrome

Research: It's all about patients

[MUSIC PLAYING]

Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight.