Transsphenoidal surgery

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Transsphenoidal care at Mayo Clinic

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AboutCare at Mayo Clinic
May 17, 2025
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  1. Transsphenoidal surgery. NCI Dictionary of Cancer Terms. https://www.cancer.gov/publications/dictionaries/cancer-terms/def/transsphenoidal-surgery. Accessed April 17, 2025.
  2. Kuo JS, et al. Congress of Neurological Surgeons systematic review and evidence-based guideline on surgical techniques and technologies for the management of patients with nonfunctioning pituitary adenomas. Neurosurgery. 2016; doi:10.1227/NEU.0000000000001390.
  3. Quinones-Hinojosa A, et al., eds. Endoscopic endonasal pituitary and skull base surgery. In: Schmidek & Sweet: Operative Neurosurgical Techniques. 7th ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed April 17, 2025.
  4. Swearingen B. Transsphenoidal surgery for pituitary adenomas and other sellar masses. https://www.uptodate.com/contents/search. Accessed April 17, 2025.
  5. Winn HR, ed. Avoidance of complications in neurosurgery. In: Youmans and Winn Neurological Surgery. 8th ed. Elsevier; 2023. https://www.clinicalkey.com. Accessed April 17, 2025.
  6. Gropper MA, et al., eds. Anesthesia for neurologic surgery and neurointerventions. Miller's Anesthesia. 10th ed. 2025; Elsevier. https://www.clinicalkey.com. Accessed April 17, 2025.
  7. Guinto G, et al. Current and future perspectives of microscopic and endoscopic transsphenoidal surgery for pituitary adenomas: A narrative review. Archives of Medical Research. 2023; doi:10.1016/j.arcmed.2023.102872.
  8. Fang CH, et al. Overview of pituitary surgery. Otolaryngologic Clinics of North America. 2022; doi:10.1016/j.otc.2022.01.001.
  9. Rennert RC, et al. Microscopic transsphenoidal surgery in the era of endoscopy: Are there any advantages? Otolaryngologic Clinics of North America. 2022; doi:10.1016/j.otc.2021.12.010.
  10. Chavez-Herrera VR, et al. Endonasal endoscopic surgery for pituitary adenomas. Clinical Neurology and Neurosurgery. 2024; doi:10.1016/j.clineuro.2024.108172.
  11. Shafiq I, et al. Advancement in perioperative management of pituitary adenomas — Current concepts and best practices. Journal of Neuroendocrinology. 2024; doi:10.1111/jne.13427.
  12. Perez-Vega C, et al. Fluid restriction after transsphenoidal surgery for the prevention of delayed hyponatremia: A systematic review and meta-analysis. Endocrine Practice. 2021; doi:10.1016/j.eprac.2021.07.003.
  13. Zhou Z, et al. Risk factors for postoperative cerebrospinal fluid leakage after transsphenoidal surgery for pituitary adenoma: A meta-analysis and systematic review. BMC Neurology. 2021; doi:10.1186/s12883-021-02440-0.
  14. Pituitary tumors treatment — For health professionals. National Cancer Institute. http://www.cancer.gov/types/pituitary/hp/pituitary-treatment-pdq#section/all. Accessed May 2, 2025.
  15. Surgery for pituitary tumors. American Cancer Society. https://www.cancer.org/cancer/types/pituitary-tumors/treating/surgery.html. Accessed April 25, 2025.
  16. Swearingen, B. Transsphenoidal surgery for pituitary adenomas and other sellar masses. https://www.uptodate.com/contents/search. Accessed April 25, 2025.
  17. Shih HA. Radiation therapy of pituitary tumors. https://www.uptodate.com/contents/search. Accessed April 25, 2025.
  18. Health Education & Content Services. Endoscopic transsphenoidal pituitary surgery. Mayo Clinic; 2023.
  19. Health Education & Content Services. Preparing for your surgery or procedure. Mayo Clinic; 2023.

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Transsphenoidal surgery