Mayo Clinic's approach

Kidney transplant consultation at Mayo Clinic Kidney transplant consultation

Kidney transplant consultation at Mayo Clinic

Teamwork

At Mayo Clinic, an integrated team of doctors trained in kidney disease (nephrologists), abdominal transplant surgery, infectious disease management and other specialties is focused on the needs of you and your family. Surgeons, doctors, transplant nurses, pharmacists, social workers and others work together to manage every aspect of your kidney transplant, from planning through postsurgical care.

Healthcare professionals trained in many medical specialties work together as a team to ensure favorable outcomes from your kidney transplant. Care team roles

Healthcare professionals trained in many medical specialties work together as a team to ensure favorable outcomes from your kidney transplant.

Coordinated care

Having all of this subspecialized expertise in a single place, focused on you, means that you're not just getting one opinion — your care is discussed among the team, your test results are available quickly, appointments are scheduled in coordination, and your transplant care team works together to determine what's best for you.

Surgical expertise

At Mayo Clinic, surgeons perform more than 650 kidney transplants a year, including numerous complex surgical procedures at campuses in Arizona, Florida and Minnesota. As a three-site institution, Mayo Clinic has one of the largest living-donor kidney transplant and paired kidney donor programs in the United States.

Our experts have pioneered many procedures, including living-donor kidney transplants and kidney transplant before dialysis is needed. The Mayo Clinic kidney transplant team has extensive experience in the most complex types of kidney transplantation, including ABO incompatible, positive crossmatch and paired donation kidney transplants.

Mayo Clinic in Rochester, Minnesota, is ranked as the best hospital in the nation for diabetes and endocrinology by U.S. News & World Report. Mayo Clinic in Phoenix/Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, are ranked among the Best Hospitals for diabetes and endocrinology by U.S. News & World Report.

Pediatric kidney transplant surgery also is provided to children at Mayo Clinic in Rochester, Minnesota, and Phoenix/Scottsdale, Arizona.

Mayo Clinic also offers kidney transplants to select candidates with hepatitis B and C and treated HIV.

Kidney transplant outcomes at Mayo Clinic compare favorably with the national average.

Start your donor evaluation

Begin the process of becoming a living kidney or liver donor by clicking here to complete a health history questionnaire.

Research

Researchers at Mayo Clinic are actively engaged in developing new technologies, treatments and techniques to make transplants safer and available to more people.

Mayo Clinic researchers were part of a major U.S. study that pioneered a new pretransplant immune system treatment to expand the use of incompatible living-donor kidney transplants — an innovation that means less time on dialysis waiting for a perfect match for many people whose immune systems previously wouldn't tolerate a living-donor kidney.

At Mayo Clinic, you may have access to ongoing clinical trials, research and new treatments.

Mayo Clinic researchers actively study medicines and treatments for people with kidney transplants, including new medicines (immunosuppressive medicines) to keep your body from rejecting your kidney transplant.

Researchers also are investigating better ways to lower antibody levels in your blood to reduce rejection of a donor kidney and improve outcomes when the match between a donor and recipient isn't ideal (ABO incompatible and positive crossmatch kidney transplants).

Other research areas include looking at new ways to use immunosuppressive medicines, including tacrolimus (Prograf, Astagraf XL), sirolimus (Rapamune), belatacept (Nulojix) and steroid-free immunosuppression medicine options, to help reduce side effects and complications for people with kidney transplants.

Read more about the Kidney and Pancreas Transplant Research Program.

Nationally recognized expertise

At Mayo Clinic, surgeons perform more than 650 kidney transplants a year, including numerous complex surgical procedures at campuses in Arizona, Florida and Minnesota. As a three-site institution, Mayo Clinic has one of the largest living-donor kidney transplant and paired kidney donor programs in the United States.

Our experts have pioneered many procedures, including living-donor kidney transplants and kidney transplant before dialysis is needed. The Mayo Clinic kidney transplant team has extensive experience in the most complex types of kidney transplantation, including ABO incompatible, positive crossmatch and paired donation kidney transplants.

Mayo Clinic in Rochester, Minnesota, is ranked as the best hospital in the nation for diabetes and endocrinology by U.S. News & World Report. Mayo Clinic in Phoenix/Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, are ranked among the Best Hospitals for diabetes and endocrinology by U.S. News & World Report.

Expertise and rankings

Kidney transplant interdisciplinary teamwork at Mayo Clinic Kidney transplant interdisciplinary team

Kidney transplant interdisciplinary teamwork at Mayo Clinic

Experience

Mayo Clinic kidney transplant surgeons have performed more than 7,000 procedures using state-of-the-art technology since performing their first kidney transplant in 1963.

At Mayo Clinic, surgeons perform more than 650 kidney transplants a year, including numerous complex surgical procedures at campuses in Arizona, Florida and Minnesota. As a three-site institution, Mayo Clinic has one of the largest living-donor kidney transplant and paired kidney donor programs in the United States.

Our experts have pioneered many procedures, including living-donor kidney transplants and kidney transplant before dialysis is needed. The Mayo Clinic kidney transplant team has extensive experience in the most complex types of kidney transplantation, including ABO incompatible, positive crossmatch and paired donation kidney transplants.

Mayo Clinic in Rochester, Minnesota, is ranked as the best hospital in the nation for diabetes and endocrinology by U.S. News & World Report. Mayo Clinic in Phoenix/Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, are ranked among the Best Hospitals for diabetes and endocrinology by U.S. News & World Report.

Innovation and research

Mayo Clinic transplant researchers take a leading role in efforts to find new, improved ways to conduct all aspects of transplantation. This includes expanding the availability of transplants, reducing risks and improving the outcomes of transplantation.

Our experts have pioneered many procedures, including living-donor kidney transplants and kidney transplant before dialysis is needed.

The Mayo Clinic Transplant Center supports many studies for kidney transplant research.

Kidney transplant research at Mayo Clinic Kidney transplant research at Mayo Clinic

Nationally recognized expertise

Kidney transplant outcomes at Mayo Clinic compare favorably with the national average.

At Mayo Clinic, surgeons perform more than 650 kidney transplants a year, including numerous complex surgical procedures at campuses in Arizona, Florida and Minnesota. As a three-site institution, Mayo Clinic has one of the largest living-donor kidney transplant and paired kidney donor programs in the United States.

Our experts have pioneered many procedures, including living-donor kidney transplants and kidney transplant before dialysis is needed. The Mayo Clinic kidney transplant team has extensive experience in the most complex types of kidney transplantation, including ABO incompatible, positive crossmatch and paired donation kidney transplants.

Mayo Clinic in Rochester, Minnesota, is ranked as the best hospital in the nation for diabetes and endocrinology by U.S. News & World Report. Mayo Clinic in Phoenix/Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, are ranked among the Best Hospitals for diabetes and endocrinology by U.S. News & World Report.

Volumes and outcomes

 

Mayo Clinic doctors' experience and integrated team approach results in transplant outcomes that compare favorably with national averages. Teams work with transplant recipients before, during and after surgery to ensure the greatest likelihood of superior results.

Volumes and statistics are maintained separately for the three Mayo Clinic locations. Taken together or separately, transplant recipients at Mayo Clinic enjoy excellent results.

Locations, travel and lodging

Mayo Clinic Transplant Center offers care and housing for transplant patients and their families in Arizona, Florida and Minnesota.

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Kidney transplant costs and insurance information

Mayo Clinic has dedicated transplant financial services representatives and social workers who can assist you with insurance and financial questions regarding your transplant.

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people. In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. Many insurance companies require you to get preapproval authorization prior to transplant services.

Insurance information

Before your transplant, it's important that you work closely with your insurance company to understand your benefit plan. You'll be responsible for any of your transplant and medical care costs not covered by your insurance company.

You may want to ask your insurance company several questions regarding your transplant expenses, including:

  • What is the specific coverage of my plan? What are my deductibles, coinsurance, copayments, lifetime maximum amount and annual maximum amounts for both medical care and transplant services?
  • Does my plan have a preexisting or waiting period clause? If so, what is the time frame? Can this be waived?
  • Does my plan include pharmacy coverage? If so, will my plan cover my current medicines and immunosuppressant medicines?
  • Does my plan require any special approvals for evaluation or transplant? How long does the approval process take once submitted to insurance?
  • Does my plan cover my transportation and lodging expenses during my transplant care?
  • Does my current insurance require enrollment in Medicare when eligible?
  • Does my insurance follow Medicare Coordination of Benefits guidelines?
  • How will my current coverage change after enrolling in Medicare? Will my plan become a supplemental or secondary plan?

If your plan is a Medicare supplement, ask questions including:

  • Does my plan follow Medicare guidelines?
  • Does my plan cover Medicare Parts A and B deductible and coinsurance?
  • Does my plan have a preexisting or waiting period clause? If so, what is the time frame?
  • Does my plan offer an option for Medicare Part D coverage?

Other expenses

Please plan for other expenses that may occur related to your transplant, which may include follow-up medical appointments, long-term medicines, caregiver expenses, travel, parking, lodging and other expenses.

For international patients

Mayo Clinic has dedicated international patient account representatives who can assist you with questions regarding your costs and insurance. Read more about international financial services.

Case managers

Mayo Clinic financial staff will work closely with your case managers from your insurance company. Your case manager, who is assigned to you, is available to answer questions and calls related to your insurance costs.

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

Sept. 05, 2025
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  11. Chandraker A, et al. Overview of care of the adult kidney transplant recipient. https://www.uptodate.com/contents/search. Accessed Jan. 8, 2025.
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  15. Medical review (expert opinion). Mayo Clinic. April 10, 2025.
  16. The organ transplant process. Health Resources & Services Administration. https://www.organdonor.gov/learn/process/transplant-process. Accessed Jan. 8, 2025.
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  19. Living donation. UNOS. https://unos.org/transplant/living-donation/. Accessed Jan. 8, 2025.
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  21. Vella J. Kidney transplantation in adults: Risk factors for graft failure. https://www.uptodate.com/contents/search. Accessed Jan. 8, 2025.
  22. Knechtle SJ, et al. Kidney Transplantation: Principles and Practice. 8th ed. Elsevier; 2020. https://www.clinicalkey.com. Accessed Jan. 8, 2025.
  23. Marks WH, et al. Safety and efficacy of eculizumab in the prevention of antibody-mediated rejection in living-donor kidney transplant recipients requiring desensitization therapy: A randomized trial. American Journal of Transplantation. 2019; doi:10.1111/ajt.15364.
  24. Diet after kidney transplant. National Kidney Foundation. https://www.kidney.org/kidney-topics/diet-after-kidney-transplant. Accessed Jan. 20, 2025.
  25. Emotional aspects of waiting. UNOS Transplant Living. https://transplantliving.org/before-the-transplant/waiting-for-your-transplant/emotional-aspects-of-waiting/. Accessed Jan. 8, 2025.
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  27. Orandi BJ, et al. Survival benefit with kidney transplants from HLA-incompatible live donors. New England Journal of Medicine. 2016; doi:10.1056/NEJMoa1508380.
  28. Organ Procurement Organization statistics. Scientific Registry of Transplant Recipients. https://www.srtr.org/reports/opo-specific-reports/interactive-report. Accessed Jan. 8, 2025.

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