Departments and specialties

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

Doctors who perform this procedure

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Research

A team of doctors talk about 3D printing. Mayo Clinic team discussion

A team of healthcare professionals talk about research and technology, including 3D printing of models of the heart.

Mayo Clinic cardiologists, cardiovascular surgeons and other healthcare professionals study new ways to do heart valve repair and heart valve replacement. Topics of research have included:

  • Catheter treatments for heart valve repair and replacement.
  • Minimally invasive heart valve surgery.
  • New treatments for heart valve disease.
  • The use of 3D printing to make models of the heart and valves to prepare for heart valve surgery.

Learn more about research in the Cardiovascular Research Center.

Publications

See a list of publications about heart valve surgery by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

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June 06, 2026
  1. Heart valve diseases: Treatment. National Heart, Lung, and Blood Institute. https://www.nhlbi.nih.gov/health/heart-valve-diseases/treatment. Accessed May 8, 2025.
  2. Heart surgery: Recovery. National Heart, Lung, and Blood Institute. https://www.nhlbi.nih.gov/health/heart-surgery/recovery. Accessed May 8, 2025.
  3. Understanding your heart valve treatment options. American Heart Association. https://www.heart.org/en/health-topics/heart-valve-problems-and-disease/understanding-your-heart-valve-treatment-options. Accessed May 8, 2025.
  4. Townsend CM Jr, et al. Acquired heart disease: Valvular. In: Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice. 21st ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed May 8, 2025.
  5. Harris KM. Allscripts EPSi. Mayo Clinic. April 28, 2025.
  6. Office of Patient Education. Heart surgery: Getting ready, surgery and your time in the hospital. Mayo Clinic; 2021.
  7. Otto CM, et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Journal of the American College of Cardiology. 2021; doi:10.1016/j.jacc.2020.11.018.
  8. Hillis GS, et al. Is asymptomatic severe aortic stenosis still a waiting game? Circulation. 2022; doi:10.1161/CIRCULATIONAHA.121.058598.
  9. Medical review (expert opinion). Mayo Clinic. May 12, 2025.
  10. Sengupta PP, et al. The future of valvular heart disease assessment and therapy. Lancet. 2024; doi:10.1016/S0140-6736(23)02754-X.
  11. Heart valve disease. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/heart-valve-disease/symptoms-causes/syc-20353727. Accessed May 7, 2025.
  12. Heart valve disease resources: Considerations for surgery: How can I prepare for surgery? American Heart Association. https://www.heart.org/en/health-topics/heart-valve-problems-and-disease/heart-valve-disease-resources. Accessed May 8, 2025.
  13. Mitral valve repair and replacement. Mayo Clinic. https://www.mayoclinic.org/tests-procedures/mitral-valve-repair-mitral-valve-replacement/about/pac-20384958. Accessed May 8, 2025.
  14. Tavakoli K, et al. Short-term, mid-term, and long-term outcomes of transcatheter aortic valve replacement with balloon-expandable versus self-expanding valves: A meta-analysis of randomized controlled trials. Clinical Cardiology. 2025; doi:10.1002/clc.70134.
  15. Vahanian A, et al.2021 ESC/EACTS Guidelines for the management of valvular heart disease. European Heart Journal. 2022; doi:10.1093/eurheartj/ehab395.