Your kidneys filter waste products from your blood while retaining what your body needs — including proteins. However, some diseases and conditions allow proteins to pass through the filters of your kidneys, causing protein in urine.

Conditions that can cause a temporary rise in the levels of protein in urine, but don't necessarily indicate kidney damage, include:

  1. Dehydration
  2. Emotional stress
  3. Exposure to extreme cold
  4. Fever
  5. Strenuous exercise

Diseases and conditions that can cause persistently elevated levels of protein in urine, which might indicate kidney disease, include:

  1. Amyloidosis (buildup of abnormal proteins in your organs)
  2. Certain drugs, such as nonsteroidal anti-inflammatory drugs
  3. Chronic kidney disease
  4. Diabetes
  5. Endocarditis (an infection of the inner lining of the heart)
  6. Focal segmental glomerulosclerosis (FSGS)
  7. Glomerulonephritis (inflammation in the kidney cells that filter waste from the blood)
  8. Heart disease
  9. Heart failure
  10. High blood pressure (hypertension)
  11. Hodgkin's lymphoma (Hodgkin's disease)
  12. IgA nephropathy (Berger's disease) (kidney inflammation resulting from a buildup of the antibody immunoglobulin A)
  13. Kidney infection (pyelonephritis)
  14. Lupus
  15. Malaria
  16. Multiple myeloma
  17. Nephrotic syndrome (damage to small filtering blood vessels in the kidneys)
  18. Orthostatic proteinuria (urine protein level rises when in an upright position)
  19. Preeclampsia
  20. Pregnancy
  21. Rheumatoid arthritis (inflammatory joint disease)
  22. Sarcoidosis (collections of inflammatory cells in the body)
  23. Sickle cell anemia

Causes shown here are commonly associated with this symptom. Work with your doctor or other health care professional for an accurate diagnosis.

April 21, 2020