To diagnose sclerosing mesenteritis your doctor may do a physical exam. You might have an image taken of your stomach and abdomen with a CT scan or an MRI. Your doctor may also insert a long needle through your skin to take a sample of the affected tissue and examine it under a microscope.


Treatment for sclerosing mesenteritis may not be necessary. Especially if you don't have symptoms. Instead, your doctor may keep track of your condition with imaging tests like an MRI or CT scan. If you are having symptoms you might take a steroid medication like prednisone to control swelling. You may also start hormone therapy to slow the growth of scar tissue. You may need surgery if blood flow through your digestive system becomes blocked.

Sclerosing mesenteritis care at Mayo Clinic

Dec. 20, 2018
  1. Friedman LS. Sclerosing mesenteritis. http://www.uptodate.com/home. Accessed Aug. 31, 2016.
  2. Akram S, et al. Sclerosing mesenteritis: Clinical features, treatment and outcome in 92 patients. Clinical Gastroenterology and Hepatology. 2007;5:589.
  3. Brown AY. Allscripts EPSi. Mayo Clinic, Rochester, Minn. July 25, 2016.
  4. Vlachos K, et al. Sclerosing mesenteritis: Diverse clinical presentations and dissimilar treatment options. A case series and review of the literature. International Archives of Medicine. 2011;4:17.
  5. Feldman M, et al. Surgical peritonitis and other diseases of the peritoneum, mesentery, omentum, and diaphragm. In: Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 10th ed. Philadelphia, Pa.: Saunders Elsevier; 2016. http://www.clinicalkey.com. Accessed Aug. 31, 2016.
  6. U.S. News best hospitals 2016-2017. U.S. News & World Report. http://health.usnews.com/best-hospitals/area/mn/mayo-clinic-6610451/gastroenterology-and-gi-surgery. Accessed Sept. 6, 2016.
  7. Picco MF (expert opinion). Mayo Clinic, Jacksonville, Fla. Sept. 7, 2016.