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Polycystic kidney disease

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Displaying 1-10 out of 17 doctors available

  1. Fouad T. Chebib, M.D.

    Fouad T. Chebib, M.D.

    1. Jacksonville, FL
    Areas of focus:

    Kidney dialysis, Pancreas transplant, Kidney transplant, Transplant, Chronic kidney disease, High blood pressure, End-s...tage renal disease, Kidney cyst, Polycystic kidney disease, Acute kidney failure, Kidney stone, Glomerular disease

  2. Carl H. Cramer, II, M.D.

    Carl H. Cramer, II, M.D.

    1. Pediatrician
    2. Pediatric Nephrologist
    3. Internist
    1. Rochester, MN
    Areas of focus:

    Peritoneal dialysis, Kidney transplant, Hemodialysis, Dialysis, Kidney infection, High blood pressure in children, Memb...ranoproliferative glomerulonephritis, Renal artery stenosis, UTI, Single kidney, Protein in urine, Congenital kidney disorder, Horseshoe kidney, Blood in urine, Polycystic kidney disease, Minimal change disease, Renovascular disease, High blood pressure, Postural proteinuria, Hydronephrosis, Acute kidney injury , Chronic kidney disease, Renal tubular acidosis, Medullary sponge kidney, Childhood nephrotic syndrome, Focal segmental glomerulosclerosis, Kidney cyst, End-stage renal disease, Shrinking kidney, Multicystic kidney dysplasia

  3. Peter M. Fitzpatrick, M.D.

    Peter M. Fitzpatrick, M.D.

    1. Nephrologist
    2. Internist
    1. Jacksonville, FL
    Areas of focus:

    Continuous renal replacement therapy, Dialysis, End-stage renal disease, Kidney stone, Chronic kidney disease, Kidney f...ailure, Polycystic kidney disease

  4. Christian Hanna, M.D., M.S.

    Christian Hanna, M.D., M.S.

    1. Pediatric Nephrologist
    1. Rochester, MN
    Areas of focus:

    Continuous renal replacement therapy, Peritoneal dialysis, Kidney transplant, Dialysis, Hemodialysis, Horseshoe kidney,... Membranous nephropathy, Medullary sponge kidney, Kidney infection, Protein in urine, Acute kidney injury , Minimal change disease, Kidney stone, Blood in urine, Multicystic kidney dysplasia, UTI, High blood pressure in children, Chronic kidney disease, Glomerular disease, Renal tubular acidosis, Kidney cyst, Polycystic kidney disease, Congenital kidney disorder, End-stage renal disease, Postural proteinuria, Membranoproliferative glomerulonephritis, Renovascular disease, Hemolytic uremic syndrome, Nephrotic syndrome, Renal artery stenosis, Hydronephrosis, Single kidney, Focal segmental glomerulosclerosis, Inherited cystic kidney disorder, Childhood nephrotic syndrome, IgA nephropathy

  5. Marie C. Hogan, M.D., Ph.D.

    Marie C. Hogan, M.D., Ph.D.

    1. Nephrologist
    2. Internist
    1. Rochester, MN
    Areas of focus:

    End-stage renal disease, Polycystic kidney disease, Glomerular disease, Focal segmental glomerulosclerosis, IgA nephrop...athy

  6. Musab S. Hommos, M.B.B.S.

    Musab S. Hommos, M.B.B.S.

    1. Nephrologist
    1. Phoenix, AZ
    Areas of focus:

    Polycystic kidney disease, Chronic kidney disease, Amyloidosis, Renal tubular acidosis, High blood pressure, Glomerulon...ephritis, Renal artery stenosis, Acute kidney injury , End-stage renal disease

  7. Tambi Jarmi, M.D.

    Tambi Jarmi, M.D.

    1. Transplant Nephrologist
    2. Nephrologist
    1. Jacksonville, FL
    Areas of focus:

    Kidney transplant, Post-transplant long-term care, Immunosuppressive drug therapy, Pre-transplant evaluation, Pancreas ...transplant, Chronic kidney disease, End-stage renal disease, Polycystic kidney disease, Diabetic nephropathy, Acute kidney failure

  8. Napat Leeaphorn, M.D.

    Napat Leeaphorn, M.D.

    1. Transplant Nephrologist
    1. Jacksonville, FL
    Areas of focus:

    Continuous renal replacement therapy, Pre-transplant evaluation, Kidney transplant, Dialysis, Hemodialysis, Pancreas tr...ansplant, Immunosuppressive drug therapy, Post-transplant long-term care, Kidney failure, Chronic kidney disease, Transplant rejection, Polycystic kidney disease, Acute kidney failure, End-stage renal disease, Diabetic nephropathy

  9. Martin L. Mai, M.D.

    Martin L. Mai, M.D.

    1. Internist
    2. Nephrologist
    3. Transplant Nephrologist
    1. Jacksonville, FL
    Areas of focus:

    Kidney transplant, Immunosuppressive drug therapy, Post-transplant long-term care, Pancreas transplant, Pre-transplant ...evaluation, Chronic kidney disease, Diabetic nephropathy, End-stage renal disease, Kidney failure, Polycystic kidney disease, Acute kidney failure

  10. Katherine Oshel, M.D.

    Katherine Oshel, M.D.

    1. Nephrologist
    2. Transplant Nephrologist
    3. Internist
    1. Jacksonville, FL
    Areas of focus:

    Pancreas transplant, Post-transplant long-term care, Pre-transplant evaluation, Immunosuppressive drug therapy, Kidney ...transplant, Diabetic nephropathy, End-stage renal disease, Kidney injury, Acute kidney failure, Chronic kidney disease, Polycystic kidney disease

Research

Mayo Clinic is a leader in polycystic kidney disease research. Mayo Clinic researchers discovered:

  • The main gene that causes autosomal dominant polycystic kidney disease (ADPKD)
  • The gene that causes autosomal recessive polycystic kidney disease (ARPKD)
  • A gene that causes a rare form of polycystic kidney disease associated with multiple malformations (Meckel-Gruber syndrome)
  • The polycystic kidney disease proteins polycystin 1, polycystin 2 and fibrocystin
  • The polycystic kidney and liver disease gene GANAB
  • Other genes that cause kidney cyst disease, such as DNAJB11
  • A way to use CT and MRI scans to classify polycystic kidney disease and select people for clinical trials of new therapies
  • A pioneering approach to surgery to remove diseased kidneys and transplant healthy kidneys during the same surgery

Lab-based research at Mayo Clinic has focused on:

  • Explaining how mutations in the polycystic kidney disease genes lead to cyst development
  • Preclinical studies in drug therapies for polycystic kidney disease, such as octreotide and vasopressin antagonists
  • Finding effective therapies for polycystic kidney disease and liver disease
  • Improving imaging assessments of polycystic kidney and liver disease
  • Studies of polycystic kidney disease proteins in urine particles known as exosomes
  • Testing new compounds in animal models of polycystic kidney disease
  • Studies of the hairlike structures (primary cilia) implicated in polycystic kidney disease

Mayo research has shown that a new drug (tolvaptan) can dramatically slow the development and progression of polycystic kidney disease in animal models.

Mayo researchers have also shown that another drug (octreotide) delays the development of both polycystic kidney disease and polycystic liver disease and is a potential treatment option for people with liver involvement.

These medications are now in clinical trials and tolvaptan is approved for use in some countries for polycystic kidney disease. In addition, nephrologists at Mayo Clinic are working to understand how to prevent the progression of kidney (renal) disease in patients with polycystic kidney disease.

Read more about the extensive research being done at Mayo Clinic's Robert M. and Billie Kelley Pirnie Translational Polycystic Kidney Disease (PKD) Center.

The Mayo Nephrology Collaborative Group — a consortium of nephrologists located across the United States — develops and conducts studies aimed at improving treatment of patients with renal diseases, including polycystic kidney disease.

Publications

See a list of publications by Mayo Clinic doctors on polycystic kidney disease on PubMed, a service of the National Library of Medicine.

Research Profiles

By Mayo Clinic Staff

Polycystic kidney disease care at Mayo Clinic

Request an Appointment at Mayo Clinic
Diagnosis & treatmentCare at Mayo Clinic
Nov. 24, 2022
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