Departments and specialties

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

Doctors who treat this condition

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Displaying 1-7 out of 7 doctors available

  1. Fouad T. Chebib, M.D.

    Fouad T. Chebib, M.D.

    1. Rochester, Minnesota
    Areas of focus:

    Kidney dialysis, Kidney transplant, Pancreas transplant, Transplant, Acute kidney failure, Chronic kidney disease, Glomerular disease, High blood pressure, Kidney cyst, Kidney stone, Polycystic kidney disease more

    see full list in profile
  2. Carl H. Cramer, II, M.D.

    Carl H. Cramer, II, M.D.

    1. Internist
    2. Pediatric Nephrologist
    3. Pediatrician
    1. Rochester, Minnesota
    Areas of focus:

    Dialysis, Kidney transplant, Blood in urine NOS, Chronic kidney disease, Congenital kidney disorder, High blood pressure, Polycystic kidney disease, Protein in urine, Renal artery stenosis, Renal tubular acidosis more

    see full list in profile
  3. Ziad M. El-Zoghby, M.D.

    Ziad M. El-Zoghby, M.D.

    1. Internist
    2. Nephrologist
    1. Rochester, Minnesota
    Areas of focus:

    Dialysis, Kidney donation, Kidney transplant, Liver transplant, Living donor kidney transplant, Acute kidney failure, Chronic kidney disease, Glomerular disease, Kidney failure, Polycystic kidney disease more

    see full list in profile
  4. Peter M. Fitzpatrick, M.D.

    Peter M. Fitzpatrick, M.D.

    1. Internist
    2. Nephrologist
    1. Jacksonville, Florida
    Areas of focus:

    Continuous renal replacement therapy, Dialysis, Chronic kidney disease, Kidney failure, Kidney stone, Polycystic kidney disease more

    see full list in profile
  5. Marie C. Hogan, M.D., Ph.D.

    Marie C. Hogan, M.D., Ph.D.

    1. Internist
    2. Nephrologist
    1. Rochester, Minnesota
    Areas of focus:

    Focal segmental glomerulosclerosis, Glomerular disease, Polycystic kidney disease more

    see full list in profile
  6. Qi Qian, M.D.

    Qi Qian, M.D.

    1. Nephrologist
    1. Rochester, Minnesota
    Areas of focus:

    Intensive care, Chronic kidney disease, Congenital kidney disorder, High blood pressure, Kidney injury, Kidney stone, Polycystic kidney disease more

    see full list in profile
  7. Vicente E. Torres, M.D., Ph.D.

    Vicente E. Torres, M.D., Ph.D.

    1. Internist
    2. Nephrologist
    1. Rochester, Minnesota
    Areas of focus:

    Kidney transplant, Pancreas transplant, Transplant, Glomerular disease, Kidney failure, Kidney stone, Polycystic kidney disease more

    see full list in profile

Research

Mayo Clinic is a leader in polycystic kidney disease research. Mayo Clinic researchers discovered:

  • The main gene that causes autosomal dominant polycystic kidney disease (ADPKD)
  • The gene that causes autosomal recessive polycystic kidney disease (ARPKD)
  • A gene that causes a rare form of polycystic kidney disease associated with multiple malformations (Meckel-Gruber syndrome)
  • The polycystic kidney disease proteins polycystin 1, polycystin 2 and fibrocystin
  • The polycystic kidney and liver disease gene GANAB
  • A way to use CT and MRI scans to classify polycystic kidney disease and select people for clinical trials of new therapies

Lab-based research at Mayo Clinic has focused on:

  • Explaining how mutations in the polycystic kidney disease genes lead to cyst development
  • Preclinical studies in drug therapies for polycystic kidney disease, such as octreotide and vasopressin antagonists
  • Finding effective therapies for polycystic kidney disease and liver disease
  • Improving imaging assessments of polycystic kidney and liver disease
  • Studies of polycystic kidney disease proteins in urine particles known as exosomes
  • Testing new compounds in animal models of polycystic kidney disease
  • Studies of the hairlike structures (primary cilia) implicated in polycystic kidney disease

Mayo research has shown that a new drug (tolvaptan) can dramatically slow the development and progression of polycystic kidney disease in animal models.

Mayo researchers have also shown that another drug (octreotide) delays the development of both polycystic kidney disease and polycystic liver disease and is a potential treatment option for people with liver involvement.

These medications are now in clinical trials and tolvaptan is approved for use in some countries for polycystic kidney disease. In addition, nephrologists at Mayo Clinic are working to understand how to prevent the progression of kidney (renal) disease in patients with polycystic kidney disease.

Read more about the extensive polycystic kidney disease research taking place at Mayo Clinic.

The Mayo Nephrology Collaborative Group — a consortium of nephrologists located across the United States — develops and conducts studies aimed at improving treatment of patients with renal diseases, including polycystic kidney disease.

Publications

See a list of publications by Mayo doctors on polycystic kidney disease on PubMed, a service of the National Library of Medicine.

Research Profiles

Polycystic kidney disease care at Mayo Clinic

March 06, 2018